Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin (original) (raw)

• Tracey, K. J. et al. Shock and tissue injury induced by recombinant human cachectin. Science 234, 470–474 (1986).
  Article ADS CAS PubMed Google Scholar
• Dinarello, C. A. The interleukin-1 family: 10 years of discovery. FASEB J. 8, 1314–1325 (1994).
  Article CAS PubMed Google Scholar
• Wang, H. et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 285, 248–251 ( 1999).
  Article CAS PubMed Google Scholar
• Nathan, C. F. Secretory products of macrophages. J. Clin. Invest. 79, 319–326 (1987).
  Article CAS PubMed PubMed Central Google Scholar
• Besedovsky, H., Rey, D. A., Sorkin, E. & Dinarello, C. A. Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones. Science 233, 652–654 ( 1986).
  Article ADS CAS PubMed Google Scholar
• Woiciechowsky, C. et al. Sympathetic activation triggers systemic interleukin-10 release in immunodepression induced by brain injury. Nature Med. 4, 808–813 (1998).
  Article CAS PubMed Google Scholar
• Hu, X. X., Goldmuntz, E. A. & Brosnan, C. F. The effect of norepinephrine on endotoxin-mediated macrophage activation. J. Neuroimmunol. 31, 35–42 (1991).
  Article CAS PubMed Google Scholar
• Lipton, J. M. & Catania, A. Anti-inflammatory actions of the neuroimmunomodulator alpha-MSH. Immunol. Today 18, 140–145 (1997).
  Article CAS PubMed Google Scholar
• Watkins, L. R. & Maier, S. F. Implications of immune-to-brain communication for sickness and pain. Proc. Natl Acad. Sci. USA 96, 7710–7713 ( 1999).
  Article ADS CAS PubMed PubMed Central Google Scholar
• Sternberg, E. M. Neural-immune interactions in health and disease. J. Clin. Invest. 100, 2641–2647 ( 1997).
  Article CAS PubMed PubMed Central Google Scholar
• Scheinman, R. I., Cogswell, P. C., Lofquist, A. K. & Baldwin, A. S. Jr Role of transcriptional activation of IkappaB alpha in mediation of immunosuppression by glucocorticoids. Science 270, 283– 286 (1995).
  Article ADS CAS PubMed Google Scholar
• Gaykema, R. P., Dijkstra, I. & Tilders, F. J. Subdiaphragmatic vagotomy suppresses endotoxin-induced activation of hypothalamic corticotropin-releasing hormone neurons and ACTH secretion. _Endocrinolog_y 136, 4717– 4720 (1995).
  Article CAS Google Scholar
• Fleshner, M. et al. Thermogenic and corticosterone responses to intravenous cytokines (IL-1beta and TNF-alpha) are attenuated by subdiaphragmatic vagotomy. J. Neuroimmunol. 86, 134–141 (1998).
  Article CAS PubMed Google Scholar
• Watkins, L. R. et al. Blockade of interleukin-1 induced hyperthermia by subdiaphragmatic vagotomy: evidence for vagal mediation of immune-brain communication. Neurosci. Lett. 183, 27–31 (1995).
  Article CAS PubMed Google Scholar
• Romanovsky, A. A., Simons, C. T., Szekely, M. & Kulchitsky, V. A. The vagus nerve in the thermoregulatory response to systemic inflammation. Am. J. Physiol. 273, R407– R413 (1997).
  CAS PubMed Google Scholar
• Antonica, A., Magni, F., Mearini, L. & Paolocci, N. Vagal control of lymphocyte release from rat thymus. J. Auton. Nerv. Syst. 48, 187–197 (1994).
  Article CAS PubMed Google Scholar
• Guslandi, M. Nicotine treatment for ulcerative colitis. Br. J. Clin. Pharmacol. 48, 481–484 ( 1999).
  Article CAS PubMed PubMed Central Google Scholar
• Sandborn, W. J. et al. Transdermal nicotine for mildly to moderately active ulcerative colitis. A randomized, double-blind, placebo-controlled trial. Ann. Intern. Med. 126, 364–371 (1997).
  Article CAS PubMed Google Scholar
• Sher, M. E. et al. The influence of cigarette smoking on cytokine levels in patients with inflammatory bowel disease. Inflamm. Bowel Dis. 5, 73–78 (1999).
  Article CAS PubMed Google Scholar
• Sato, E., Koyama S., Okubo, Y., Kubo, K. & Sekigushi, M. Acetylcholine stimulates alveolar macrophages to release inflammatory cell chemotactic activity. Am. J. Physiol. 274, L970–L979 (1998).
  CAS PubMed Google Scholar
• Whaley, K., Lappin, D. & Barkas, T. C2 synthesis by human monocytes is modulated by a nicotinic cholinergic receptor. Nature 293, 580– 583 (1981).
  Article ADS CAS PubMed Google Scholar
• Sato, K. Z. et al. Diversity of mRNA expression for muscarinic acetylcholine receptor subtypes and neuronal nicotinic acetylcholine receptor subunits in human mononuclear leukocytes and leukemic cell lines. Neurosci. Lett. 266, 17–20 ( 1999).
  Article CAS PubMed Google Scholar
• Wathey, J. C., Nass, M. M. & Lester, H. A. Numerical reconstruction of the quantal event at nicotinic synapses. Biophys. J. 27, 145– 164 (1979).
  Article CAS PubMed PubMed Central Google Scholar
• Kumins, N. H., Hunt, J., Gamelli, R. L. & Filkins, J. P. Partial hepatoectomy reduces the endotoxin-induced peak circulating level of tumor necrosis factor in rats. Shock 5, 385–388 (1996).
  Article CAS PubMed Google Scholar
• Gregory, S. H. & Wing, E. J. Neutrophil-Kupffer-cell interaction in host defenses to systemic infections. Immunol. Today 19, 507–510 ( 1998).
  Article CAS PubMed Google Scholar
• Tracey, K. J. et al. Anti-cachectin/TNF monoclonal antibodies prevent septic shock during lethal bacteraemia. Nature 330, 662 –664 (1987).
  Article ADS CAS PubMed Google Scholar
• Madretsma, G. S. et al. Nicotine inhibits the in vitro production of interleukin 2 and tumour necrosis factor-alpha by human mononuclear cells. Immunopharmacology 35, 47–51 ( 1996).
  Article CAS PubMed Google Scholar
• van Dijk, A. P. et al. Transdermal nicotine inhibits interleukin 2 synthesis by mononuclear cells derived from healthy volunteers. Eur. J. Clin. Invest. 28, 664–671 (1998).
  Article CAS PubMed Google Scholar