Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase (original) (raw)
References
Howe, A., Aplin, A. E., Alahari, S. K. & Juliano, R. L. Integrin signaling and cell growth control. Curr. Opin. Cell Biol.10, 220–231 ( 1998). ArticleCAS Google Scholar
Assoian, R. K. & Zhu, X. Cell anchorage and the cytoskeleton as partners in growth factor dependent cell cycle progression. Curr. Opin. Cell Biol.9, 93–98 (1997). ArticleCAS Google Scholar
Schwartz, M. A. Integrins, oncogenes, and anchorage independence. J. Cell Biol.139, 575–578 ( 1997). ArticleCAS Google Scholar
Widmann, C., Gibson, S., Jarpe, M. B. & Johnson, G. L. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human . Physiol. Rev.79, 143– 180 (1999). ArticleCAS Google Scholar
Miyamoto, S., Teramoto, H., Gutkind, J. S. & Yamada, K. M. Integrins can collaborate with growth factors for phosphorylation of receptor tyrosine kinases and MAP kinase activation: roles of integrin aggregation and occupancy of receptors. J. Cell Biol.135, 1633–1642 (1996). ArticleCAS Google Scholar
Cybulsky, A. V. & McTavish, A. J. Extracellular matrix is required for MAP kinase activation and proliferation of rat glomerular epithelial cells. Biochem. Biophys. Res. Commun.231 , 160–166 (1997). ArticleCAS Google Scholar
Lin, T. H., Chen, Q., Howe, A. & Juliano, R. L. Cell anchorage permits efficient signal transduction between ras and its downstream kinases . J. Biol. Chem.272, 8849– 8852 (1997). ArticleCAS Google Scholar
Renshaw, M. W., Ren, X. D. & Schwartz, M. A. Growth factor activation of MAP kinase requires cell adhesion. EMBO J.16, 5592– 5599 (1997). ArticleCAS Google Scholar
Graves, L. M. & Lawrence, J. C. Jr, Insulin, growth factors, and cAMP: antagonism in the signal transduction pathways. Trends Endocrinol. Metabol.7, 43– 50 (1996). ArticleCAS Google Scholar
Cho-Chung, Y. S., Pepe, S., Clair, T., Budillon, A. & Nesterova, M. cAMP-dependent protein kinase: role in normal and malignant growth. Crit. Rev. Oncol. Hematol.21, 33 –61 (1995). ArticleCAS Google Scholar
Roger, P. P., Reuse, S., Maenhaut, C. & Dumont, J. E. Multiple facets of the modulation of growth by cAMP. Vitam. Horm.51 , 59–191 (1995). ArticleCAS Google Scholar
Schoenwaelder, S. M. & Burridge, K. Bidirectional signaling between the cytoskeleton and integrins. Curr. Opin. Cell Biol.11, 274–286 ( 1999). ArticleCAS Google Scholar
Aplin, A. E. & Juliano, R. L. Integrin and cytoskeletal regulation of growth factor signaling to the MAP kinase pathway. J. Cell Sci.112, 695–706 ( 1999). CAS Google Scholar
Tapon, N. & Hall, A. Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol.9, 86–92 (1997 ). ArticleCAS Google Scholar
Knaus, U. G. & Bokoch, G. M. The p21Rac/Cdc42-activated kinases (PAKs). Int. J. Biochem. Cell Biol.30, 857–862 (1998). ArticleCAS Google Scholar
King, A. J. et al. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338. Nature396, 180–183 (1998). ArticleCAS Google Scholar
Frost, J. A. et al. Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins. EMBO J.16, 6426 –6438 (1997). ArticleCAS Google Scholar
Howe, D. G. & McCarthy, K. D. A dicistronic retroviral vector and culture model for analysis of neuron-Schwann cell interactions. J. Neurosci. Methods83, 133–142 (1998). ArticleCAS Google Scholar
McDonald, R. A., Matthews, R. P., Idzerda, R. L. & McKnight, G. S. Basal expression of the cystic fibrosis transmembrane conductance regulator gene is dependent on protein kinase A activity. Proc. Natl Acad. Sci. USA92, 7560–7564 ( 1995). ArticleCAS Google Scholar
Day, R. N., Walder, J. A. & Maurer, R. A. A protein kinase inhibitor gene reduces both basal and multihormone-stimulated prolactin gene transcription. J. Biol. Chem.264, 431–436 ( 1989). CAS Google Scholar
Fong, J. H. & Ingber, D. E. Modulation of adhesion-dependent cAMP signaling by echistatin and alendronate. Biochem. Biophys. Res. Commun.221, 19–24 (1996). ArticleCAS Google Scholar
O'Connor, K. L., Shaw, L. M. & Mercurio, A. M. Release of cAMP gating by the alpha6beta4 integrin stimulates lamellae formation and the chemotactic migration of invasive carcinoma cells. J. Cell Biol.143, 1749– 1760 (1998). ArticleCAS Google Scholar
He, Y. & Grinnell, F. Stress relaxation of fibroblasts activates a cyclic AMP signaling pathway. J. Cell Biol.126, 457–464 (1994). ArticleCAS Google Scholar
Aplin, A. E., Howe, A. K. & Juliano, R. L. Cell adhesion molecules, signal transduction, and cell growth. Curr. Opin. Cell Biol.11, 737–744 (1999). ArticleCAS Google Scholar
Vilgrain, I., Chinn, A., Gaillard, I., Chambaz, E. M. & Feige, J. J. Hormonal regulation of focal adhesions in bovine adrenocortical cells: induction of paxillin dephosphorylation by adrenocorticotropic hormone. Biochem. J.332, 533– 540 (1998). ArticleCAS Google Scholar
Han, J. D. & Rubin, C. S. Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells . J. Biol. Chem.271, 29211– 29215 (1996). ArticleCAS Google Scholar
Takahashi, T., Kawahara, Y., Okuda, M. & Yokoyama, M. Increasing cAMP antagonizes hypertrophic response to angiotensin II without affecting Ras and MAP kinase activation in vascular smooth muscle cells. FEBS Lett.397, 89–92 ( 1996). ArticleCAS Google Scholar
Schoenwaelder, S. M. & Burridge, K. Evidence for a calpeptin-sensitive protein-tyrosine phosphatase upstream of the small GTPase Rho. A novel role for the calpain inhibitor calpeptin in the inhibition of protein-tyrosine phosphatases. J. Biol. Chem.274, 14359–14367 (1999). ArticleCAS Google Scholar
Padmanabhan, J., Clayton, D. & Shelanski, M. L. Dibutyryl cyclic AMP-induced process formation in astrocytes is associated with a decrease in tyrosine phosphorylation of focal adhesion kinase and paxillin. J. Neurobiol.39, 407–422 (1999). ArticleCAS Google Scholar
Troyer, D. A., Bouton, A., Bedolla, R. & Padilla, R. Tyrosine phosphorylation of focal adhesion kinase (p125FAK): regulation by cAMP and thrombin in mesangial cells. J. Am. Soc. Nephrol.7, 415– 423 (1996). CAS Google Scholar
Aplin, A. E., Howe, A., Alahari, S. K. & Juliano, R. L. Signal transduction and signal modulation by cell adhesion receptors: the role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins. Pharmacol. Rev.50, 197–263 ( 1998). CAS Google Scholar
Renshaw, M. W., Price, L. S. & Schwartz, M. A. Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase. J. Cell Biol.147, 611–618 ( 1999). ArticleCAS Google Scholar
Tang, Y., Yu, J. & Field, J. Signals from the Ras, Rac, and Rho GTPases converge on the Pak protein kinase in Rat-1 fibroblasts. Mol. Cell Biol.19, 1881–1891 (1999). ArticleCAS Google Scholar
Tang, Y. et al. Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol. Cell Biol.17, 4454– 4464 (1997). ArticleCAS Google Scholar
del Pozo, M. A., Price, L. S., Alderson, N. B., Ren, X. & Schwartz, M. A. Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK . EMBO J.19, 2008–2014 (2000). ArticleCAS Google Scholar
Faure, S. et al. Control of G2/M transition in Xenopus by a member of the p21-activated kinase (PAK) family: a link between protein kinase A and PAK signaling pathways? J. Biol. Chem.274, 3573–3579 (1999). ArticleCAS Google Scholar
Chung, C. Y. & Firtel, R. A. PAKa, a putative PAK family member, is required for cytokinesis and the regulation of the cytoskeleton in Dictyostelium discoideum cells during chemotaxis. J. Cell Biol.147, 559–576 ( 1999). ArticleCAS Google Scholar
Zhou, T. H. et al. Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase. J. Biol. Chem.275, 2513–2519 (2000). ArticleCAS Google Scholar
Zenke, F. T., King, C. C., Bohl, B. P. & Bokoch, G. M. Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity. J. Biol. Chem.274, 32565–32573 (1999). ArticleCAS Google Scholar
Westphal, R. S., Coffee, R. L. Jr, Marotta, A., Pelech, S. L. & Wadzinski, B. E. Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A. J. Biol. Chem.274, 687–692 ( 1999). ArticleCAS Google Scholar
Turner, C. E. et al. Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: a role in cytoskeletal remodeling. J. Cell Biol.145, 851–863 (1999). ArticleCAS Google Scholar
McCarty, J. H. The Nck SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events. Bioessays20, 913– 921 (1998). ArticleCAS Google Scholar
Whitmarsh, A. J. & Davis, R. J. Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals . Trends Biochem. Sci.23, 481– 485 (1998). ArticleCAS Google Scholar
Pawson, T. & Scott, J. D. Signaling through scaffold, anchoring, and adaptor proteins. Science278, 2075– 2080 (1997). ArticleCAS Google Scholar
Holt, M. R., Critchley, D. R. & Brindle, N. P. The focal adhesion phosphoprotein, VASP. Int. J. Biochem. Cell Biol.30, 307– 311 (1998). ArticleCAS Google Scholar
Dong, J. M., Leung, T., Manser, E. & Lim, L. cAMP-induced morphological changes are counteracted by the activated RhoA small GTPase and the Rho kinase ROKalpha. J. Biol. Chem.273, 22554– 22562 (1998). ArticleCAS Google Scholar
Ohta, Y., Akiyama, T., Nishida, E. & Sakai, H. Protein kinase C and cAMP-dependent protein kinase induce opposite effects on actin polymerizability . FEBS Lett.222, 305–310 (1987). ArticleCAS Google Scholar
Bonni, A. et al. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science286, 1358–1362 (1999). ArticleCAS Google Scholar
Howe, A. K. & Juliano, R. L. Distinct mechanisms mediate the initial and sustained phases of integrin-mediated activation of the Raf/MEK/mitogen-activated protein kinase cascade. J. Biol. Chem.273, 27268–27274 (1998). ArticleCAS Google Scholar
Graves, L. M. et al. Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells. Proc. Natl Acad. Sci. USA90, 10300 –10304 (1993). ArticleCAS Google Scholar
Chong, L. D., Traynor-Kaplan, A., Bokoch, G. M. & Schwartz, M. A. The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells. Cell79, 507 –513 (1994). ArticleCAS Google Scholar
Boyle, W. J., van der Geer, P. & Hunter, T. Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates. Methods Enzymol.201, 110–149 (1991). ArticleCAS Google Scholar