Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation (original) (raw)
References
Valitutti, S., Mulle, S., Cella, M., Padovan, E. & Lanzavecchia, A. Serial triggering of many T-cell receptors by a few peptide–MHC complexes. Nature375, 148–151 (1995). ArticleADSCAS Google Scholar
Viola, A. & Lanzavecchia, A. T cell activation determined by T cell receptor number and tunable thresholds. Science273, 104–106 (1996). ArticleADSCAS Google Scholar
Viola, A., Schroeder, S., Sakakibara, Y. & Lanzavecchia, A. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science283, 680–682 (1999). ArticleADSCAS Google Scholar
Monks, C. R., Feiberg, B. A., Kupfer, H., Sciaky, N. & Kupfer, A. Three-dimensional segregation of supramolecular activation clusters in T cells. Nature395, 82–86 (1998). ArticleADSCAS Google Scholar
Wulfing, C. & Davis, M. M. A receptor/cytoskeletal movement triggered by costimulation during T cell activation. Science282, 2266–2269 (1998). ArticleADSCAS Google Scholar
Cummings, R. D. & Kornfeld, S. The distribution of repeating Gal β1-4GlcNAc β1-3 sequences in asparagine-linked oligosaccharides of the mouse lymphoma cell line BW5147 and PHAR 2.1. J. Biol. Chem.259, 6253–6260 (1984). CASPubMed Google Scholar
Sato, S. & Hughes, R. C. Binding specificity of a baby hamster kidney lectin for H type I and II chains, polylactosamine glycans, and appropriately glycosylated forms of laminin and fibronectin. J. Biol. Chem.267, 6983–6990 (1992). CASPubMed Google Scholar
Knibbs, R. N., Agrwal, N., Wang, J. L. & Goldstein, I. J. Carbohydrate-binding protein 35. II. Analysis of the interaction of the recombinant polypeptide with saccharides. J. Biol. Chem.268, 14940–14947 (1993). CASPubMed Google Scholar
Perillo, N. L., Pace, K. E., Seilhamer, J. J. & Baum, L. G. Apoptosis of T cells mediated by galectin-1. Nature378, 736–739 (1995). ArticleADSCAS Google Scholar
Vespa, G. N. et al. Galectin-1 specifically modulates TCR signals to enhance TCR apoptosis but inhibit IL-2 production and proliferation. J. Immunol.162, 799–806 (1999). CASPubMed Google Scholar
Karsan, A. et al. Leukocyte Adhesion Deficiency Type II is a generalized defect of de novo GDP-fucose biosynthesis. Endothelial cell fucosylation is not required for neutrophil rolling on human nonlymphoid endothelium. J. Clin. Invest.101, 2438–2445 (1998). ArticleCAS Google Scholar
Ellies, L. G. et al. Core 2 oligosaccharide biosynthesis distinguishes between selectin ligands essential for leukocyte homing and inflammation. Immunity9, 881–890 (1998). ArticleCAS Google Scholar
Priatel, J. J. et al. The ST3Gal-I sialyltransferase controls CD8+ T lymphocyte homeostasis by modulating O-glycan biosynthesis. Immunity12, 273–283 (2000). ArticleCAS Google Scholar
Wall, K. A., Pierce, J. D. & Elbein, A. D. Inhibitors of glycoprotein processing alter T-cell proliferative responses to antigen and to interleukin 2. Proc. Natl Acad. Sci. USA85, 5644–5648 (1988). ArticleADSCAS Google Scholar
Cummings, R. D., Trowbridge, I. S. & Kornfeld, S. A mouse lymphoma cell line resistant to the leukoagglutinating lectin from Phaseolus vulgaris is deficient in UDP-GlcNAc:α-D-mannoside β1,6 N-acetylglucosaminyltransferase. J. Biol. Chem.257, 13421–13427 (1982). CASPubMed Google Scholar
Granovsky, M. et al. Suppression of tumor growth and metastasis in Mgat5-deficient mice. Nature Med.6, 306–312 (2000). ArticleCAS Google Scholar
Lafaille, J. J., Nagashima, K., Katsuki, M. & Tonegawa, S. High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice. Cell78, 399–408 (1994). ArticleCAS Google Scholar
Downward, J., Graves, J. D., Warne, P. H., Rayter, S. & Cantrell, D. A. Stimulation of p21_ras_ upon T-cell activation. Nature346, 719–723 (1990). ArticleADSCAS Google Scholar
Trevillyan, J. M., Lu, Y. L., Atluru, D., Phillips, C. A. & Bjorndahl, J. M. Differential inhibition of T cell receptor signal transduction and early activation events by a selective inhibitor of protein-tyrosine kinase. J. Immunol.145, 3223–3230 (1990). CASPubMed Google Scholar
Wang, J. et al. Atomic structure of an αβ T cell receptor (TCR) heterodimer in complex with an anti-TCR fab fragment derived from a mitogenic antibody. EMBO J.17, 10–26 (1998). Article Google Scholar
Hubbard, S. C., Kranz, D. M., Longmore, G. D., Sitkovsky, M. V. & Eisen, H. N. Glycosylation of the T-cell antigen-specific receptor and its potential role in lectin-mediated cytotoxicity. Proc. Natl Acad. Sci. USA83, 1852–1856 (1986). ArticleADSCAS Google Scholar
Reich, Z. et al. Ligand-specific oligomerization of T-cell receptor molecules. Nature387, 617–620 (1997). ArticleADSCAS Google Scholar
Reif, K. & Cantrell, D. A. Networking Rho family GTPases in lymphocytes. Immunity8, 395–401, (1998). ArticleCAS Google Scholar
Rudd, P. M. et al. Roles for glycosylation of cell surface receptors involved in cellular immune recognition. J. Mol. Biol.293, 351–366 (1999). ArticleCAS Google Scholar
Pace, K. E., Lee, C., Stewart, P. L. & Baum, L. G. Restricted receptor segregation into membrane microdomains occurs on human T cells during apoptosis induced by galectin-1. J. Immunol.163, 3801–3811 (1999). CASPubMed Google Scholar
Chung, C. D., Patel, V. P., Moran, M., Lewis, L. A. & Carrie Miceli, M. Galectin-1 induces partial TCR zeta-chain phosphorylation and antagonizes processive TCR signal transduction. J. Immunol.165, 3722–3729 (2000). ArticleCAS Google Scholar
Offner, H. et al. Recombinant human beta-galactoside binding lectin suppresses clinical and histological signs of experimental autoimmune encephalomyelitis. J. Neuroimmunol.28, 177–184 (1990). ArticleCAS Google Scholar
Barkal, N. & Leibler, S. Robustness in simple biochemical networks. Nature387, 913–917 (1997). ArticleADS Google Scholar
Oliveira-dos-Santos, A. J. et al. CD28 costimulation is crucial for the development of spontaneous autoimmune encephalomyelitis. J. Immunol.162, 4490–4495 (1999). CASPubMed Google Scholar
Moloney, D. J. et al. Fringe is a glycosyltransferase that modifies Notch. Nature406, 369–375 (2000). ArticleADSCAS Google Scholar