Regulation of c-myc expression by PDGF through Rho GTPases (original) (raw)
Brugge, J. S. & Erikson, R. L. Identification of a transformation-specific antigen induced by an avian sarcoma virus. Nature269, 346–348 (1977). ArticleCAS Google Scholar
Thomas, S. M. & Brugge, J. S. Cellular functions regulated by Src family kinases. Annu. Rev. Cell. Dev. Biol.13, 513–609 (1997). ArticleCAS Google Scholar
Kypta, R. M., Goldberg, Y., Ulug, E. T. & Courtneidge, S. A. Association between the PDGF receptor and members of the src family of tyrosine kinases. Cell62, 481–492 (1990). ArticleCAS Google Scholar
Twamley, G. M., Kypta, R. M., Hall, B. & Courtneidge, S. A. Association of Fyn with the activated platelet-derived growth factor receptor: requirements for binding and phosphorylation. Oncogene7, 1893–1901 (1992). CASPubMed Google Scholar
Twamley-Stein, G. M., Pepperkok, R., Ansorge, W. & Courtneidge, S. A. The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells. Proc. Natl Acad. Sci. USA90, 7696–7700 (1993). ArticleCAS Google Scholar
Broome, M. A. & Hunter, T. Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling. J. Biol. Chem.271, 16798–16806 (1996). ArticleCAS Google Scholar
Blake, R. A. et al. SU6656, a selective src family kinase inhibitor, used to probe growth factor signaling. Mol. Cell. Biol.20, 9018–9027 (2000). ArticleCAS Google Scholar
Barone, M. V. & Courtneidge, S. A. Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src. Nature378, 509–512 (1995). ArticleCAS Google Scholar
Abram, C. L. & Courtneidge, S. A. Src family tyrosine kinases and growth factor signaling. Exp. Cell Res.254, 1–13 (2000). ArticleCAS Google Scholar
Bishop, A. L. & Hall, A. Rho GTPases and their effector proteins. Biochem. J.348, 241–255 (2000). ArticleCAS Google Scholar
Van Aelst, L. & D'Souza-Schorey, C. Rho GTPases and signaling networks. Genes Dev.11, 2295–2322 (1997). ArticleCAS Google Scholar
Mackay, D. J. & Hall, A. Rho GTPases. J. Biol. Chem.273, 20685–20688 (1998). ArticleCAS Google Scholar
Ridley, A. J., Paterson, H. F., Johnston, C. L., Diekmann, D. & Hall, A. The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell70, 401–410 (1992). ArticleCAS Google Scholar
Hanke, J. H. et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation. J. Biol. Chem.271, 695–701 (1996). ArticleCAS Google Scholar
Blake, R. A., Garcia-Paramio, P., Parker, P. J. & Courtneidge, S. A. Src promotes PKCδ degradation. Cell Growth Differ.10, 231–241 (1999). CASPubMed Google Scholar
Waltenberger, J. et al. A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling. Circ. Res.85, 12–22 (1999). ArticleCAS Google Scholar
Kiuchi, N. et al. STAT3 is required for the gp130-mediated full activation of the c-myc gene. J. Exp. Med.189, 63–73 (1999). ArticleCAS Google Scholar
Zou, X., Rudchenko, S., Wong, K. & Calame, K. Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases. Genes Dev.11, 654–662 (1997). ArticleCAS Google Scholar
Eliceiri, B. P. et al. Selective requirement for Src kinases during VEGF-induced angiogenesis and vascular permeability. Mol. Cell4, 915–924 (1999). ArticleCAS Google Scholar
Marshall, C. J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell80, 179–185 (1995). ArticleCAS Google Scholar
Downward, J. Cell cycle: routine role for Ras. Curr. Biol.7, R258–R260 (1997). ArticleCAS Google Scholar
Eisenman, R. N. & Cooper, J. A. Signal transduction. Beating a path to Myc. Nature378, 438–439 (1995). ArticleCAS Google Scholar
Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J. & Saltiel, A. R. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl Acad. Sci. USA92, 7686–7689 (1995). ArticleCAS Google Scholar
Burbelo, P. D., Drechsel, D. & Hall, A. A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases. J. Biol. Chem.270, 29071–29074 (1995). ArticleCAS Google Scholar
Fukuhara, S., Marinissen, M. J., Chiariello, M. & Gutkind, J. S. Signaling from G protein-coupled receptors to ERK5/Big MAPK 1 involves Gαq and Gα12/13 families of heterotrimeric G proteins. Evidence for the existence of a novel Ras and Rho-independent pathway. J. Biol. Chem.275, 21730–21736 (2000). ArticleCAS Google Scholar
Aktories, K., Schmidt, G. & Just, I. Rho GTPases as targets of bacterial protein toxins. Biol. Chem.381, 421–426 (2000). ArticleCAS Google Scholar
Just, I. et al. Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature375, 500–503 (1995). ArticleCAS Google Scholar
Schmidt, G. et al. Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1. Nature387, 725–729 (1997). ArticleCAS Google Scholar
Lerm, M. et al. Deamidation of Cdc42 and Rac by Escherichia coli cytotoxic necrotizing factor 1: activation of c-Jun N-terminal kinase in HeLa cells. Infect. Immun.67, 496–503 (1999). CASPubMedPubMed Central Google Scholar
Whitehead, I. P., Campbell, S., Rossman, K. L. & Der, C. J. Dbl family proteins. Biochim. Biophys. Acta1332, F1–F23 (1997). CASPubMed Google Scholar
Cerione, R. A. & Zheng, Y. The Dbl family of oncogenes. Curr. Opin. Cell Biol.8, 216–222 (1996). ArticleCAS Google Scholar
Crespo, P., Schuebel, K. E., Ostrom, A. A., Gutkind, J. S. & Bustelo, X. R. Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product. Nature385, 169–172 (1997). ArticleCAS Google Scholar
Bustelo, X. R. Regulatory and signaling properties of the Vav family. Mol. Cell. Biol.20, 1461–1477 (2000). ArticleCAS Google Scholar
Henske, E. P. et al. Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1. Ann. Hum. Genet.59, 25–37 (1995). ArticleCAS Google Scholar
Liu, B. P. & Burridge, K. Vav2 activates Rac1, Cdc42, and RhoA downstream from growth factor receptors but not β1 integrins. Mol. Cell. Biol.20, 7160–7169 (2000). ArticleCAS Google Scholar
Klinghoffer, R. A., Sachsenmaier, C., Cooper, J. A. & Soriano, P. Src family kinases are required for integrin but not PDGFR signal transduction. EMBO J.18, 2459–2471 (1999). ArticleCAS Google Scholar
Broome, M. A. & Courtneidge, S. A. No requirement for src family kinases for PDGF signaling in fibroblasts expressing SV40 large T antigen. Oncogene19, 2867–2869 (2000). ArticleCAS Google Scholar
Kerkhoff, E. et al. Regulation of c-myc expression by Ras/Raf signalling. Oncogene16, 211–216 (1998). ArticleCAS Google Scholar
Abe, K. et al. Vav2 is an activator of Cdc42, Rac1, and RhoA. J. Biol. Chem.275, 10141–1049 (2000). ArticleCAS Google Scholar
Olson, M. F., Ashworth, A. & Hall, A. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science269, 1270–1272 (1995). ArticleCAS Google Scholar
Coso, O. A. et al. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway. Cell81, 1137–1146 (1995). ArticleCAS Google Scholar
Wang, S., Nath, N., Minden, A. & Chellappan, S. Regulation of Rb and E2F by signal transduction cascades: divergent effects of JNK1 and p38 kinases. EMBO J.18, 1559–1570 (1999). ArticleCAS Google Scholar
Perona, R. et al. Activation of the nuclear factor-κB by Rho, CDC42, and Rac-1 proteins. Genes Dev.11, 463–475 (1997). ArticleCAS Google Scholar
Decker, T. & Kovarik, P. Serine phosphorylation of STATs. Oncogene19, 2628–2637 (2000). ArticleCAS Google Scholar
Kessler, D. J., Duyao, M. P., Spicer, D. B. & Sonenshein, G. E. NF-κB-like factors mediate interleukin 1 induction of c-myc gene transcription in fibroblasts. J. Exp. Med.176, 787–792 (1992). ArticleCAS Google Scholar
Wong, K. K. et al. v-Abl activates c-myc transcription through the E2F site. Mol. Cell. Biol.15, 6535–6544 (1995). ArticleCAS Google Scholar
Joyce, D. et al. Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-κB-dependent pathway. J. Biol. Chem.274, 25245–25249 (1999). ArticleCAS Google Scholar
Marinissen, M. J., Chiariello, M., Pallante, M. & Gutkind, J. S. A network of mitogen-activated protein kinases links G protein-coupled receptors to the c-jun promoter: a role for c-Jun NH2-terminal kinase, p38s, and extracellular signal-regulated kinase 5. Mol. Cell. Biol.19, 4289–4301 (1999). ArticleCAS Google Scholar
Sears, R. et al. Multiple ras-dependent phosphorylation pathways regulate myc protein stability. Genes Dev.14, 2501–2514 (2000). ArticleCAS Google Scholar
Sears, R., Leone, G., DeGregori, J. & Nevins, J. R. Ras enhances Myc protein stability. Mol. Cell3, 169–179 (1999). ArticleCAS Google Scholar