Loose-patch recordings of single quanta at individual hippocampal synapses (original) (raw)

References

1. Jack, J., Larkman, A. U., Major, G. & Stratford, K. J. in Molecular and Cellular Mechanisms of Neurotransmitter Release(eds Stjarne, L. et al.) 275–299 (Raven, New York, (1994)).
   Book Google Scholar
2. Edwards, F. A. Anatomy and electrophysiology of fast central synapses lead to a structural model for long-term potentiation. Physiol. Rev. 75, 759–787 (1995).
   Google Scholar
3. Bekkers, J. M. & Stevens, C. F. NMDA and non-NMDA receptors are co-localized at individual excitatory synapses in cultured rat hippocampus. Nature 341, 230–233 (1989).
   Article ADS CAS Google Scholar
4. Liu, G. & Tsien, R. W. Properties of synaptic transmission at single hippocampal synaptic boutons. Nature 375, 404–408 (1995).
   Article ADS CAS Google Scholar
5. Lewis, C. A. & Faber, D. S. Inhibitory synaptic transmission in isolated patches of membrane from cultured rat spinal cord and medullary neurons. J. Neurophysiol. 76, 461–470 (1996).
   Google Scholar
6. Fatt, P. & Katz, B. Spontaneous subthreshold activity at motor nerve endings. J. Physiol. (Lond.) 117, 109–128 (1952).
   Google Scholar
7. Betz, W. J. & Bewick, G. S. Optical analysis of synaptic vesicle recycling at the frog neuromuscular junction. Science 255, 200–203 (1992).
   Google Scholar
8. Ryan, T. A.et al. The kinetics of synaptic vesicle recycling measured at single presynaptic boutons. Neuron 11, 713–724 (1993).
   Google Scholar
9. Stuehmer, W., Roberts, W. M. & Almers, W. in Single Channel Recording(eds Sakmann, B. & Neher, E.) 123–132 (Plenum, New York, (1983)).
   Book Google Scholar
10. Spruston, N., Jonas, P. & Sakmann, B. Dendritic glutamate receptors channels in rat hippocampal CA3 and CA1 pyramidal neurons. J. Physiol. (Lond.) 482, 325–352 (1995).
    Google Scholar
11. Jonas, P., Major, G. & Sakmann, B. Quantal components of unitary EPSCs at the mossy fiber synapse of CA3 pyramidal cells of rat hippocampus. J. Physiol. 472, 615–663 (1993).
    Google Scholar
12. Edwards, F. A., Konnerth, A. & Sakmann, B. Quantal analysis of inhibitory synaptic transmission in the dentate gyrus of rat hippocampal slices: a patch-clamp study. J. Physiol. (Lond.) 430, 213–249 (1990).
    Google Scholar
13. Silver, R. A., Traynelis, S. F. & Cull-Candy, S. G. Rapid-time-course miniature and evoked excitatory currents at cerebellar synapses in situ. Nature 355, 163–166 (1992).
    Article ADS CAS Google Scholar
14. Malgaroli, A. & Tsien, R. W. Glutamate-induced long term potentiation of the frequency of miniature synaptic currents in cultured hippocampal neurons. Nature 357, 134–139 (1992).
    Article ADS CAS Google Scholar
15. Larkman, A., Stratford, K. & Jack, J. Quantal analysis of excitatory synaptic action and depression in hippocampal slices. Nature 350, 344–347 (1991).
    Article ADS CAS Google Scholar
16. Stricker, A. C., Field, A. C. & Redman, S. J. Statistical analysis of amplitude fluctuations in EPSCs evoked in rat A1 pyramidal neurones in vitro. J. Physiol. (Lond.) 490, 419–441 (1996).
    Google Scholar
17. Kullmann, D. M. & Nicoll, R. A. Long-term potentiation is associated with increases in quantal content and quantal amplitude. Nature 357, 240–244 (1992).
    Article ADS CAS Google Scholar
18. Liao, D., Jones, A. & Malinow, R. Direct measurement of quantal changes underlying long-term potentiation in A1 hippocampus. Neuron 9, 1089–1097 (1992).
    Google Scholar
19. Bekkers, J. M., Richerson, G. B. & Stevens, C. F. Origin of variability in quantal size in cultured hippocampal neurons and hippocampal slices. Proc. Natl Acad. Sci. USA 87, 5359–5362 (1990).
    Google Scholar
20. Korn, H., Sur, C., Charpier, S., Legendre, P. & Faber, D. S. in Molecular and Cellular Mechanisms of Neurotransmitter Release(eds Stjarne, L. et al.) 301–322 (Raven, New York, (1994)).
    Book Google Scholar
21. Bauerfeind, R., Huttner, W. B., Almers, W. & Augustine, G. J. Quantal neurotransmitter release from early endosomes? Trends Cell Biol. 4, 155–156 (1994).
    Google Scholar
22. Jack, J. J. B., Noble, D. & Tsien, R. W. Electric Current Flow in Excitable Cells(Oxford Univ. Press, Oxford, UK, (1983)).
    Google Scholar
23. Spruston, N., Jaffe, D. B., Williams, S. H. & Johnston, D. Voltage- and space-clamp errors associated with measurement of electrotonically remote synaptic events. J. Neurophysiol. 70, 781–802 (1993).
    Google Scholar
24. Faber, D. S., Young, W. S., Legendre, P. & Korn, H. Intrinsic quantal variability due to stochastic properties of receptor–transmitter interactions. Science 258, 1494–1498 (1992).
    Google Scholar
25. Hestrin, S. Activation and desensitization of glutamate-activated channels mediating fast excitatory synaptic currents in the visual cortex. Neuron 9, 991–999 (1992).
    Google Scholar
26. Silver, R. A., Cull-Candy, S. G. & Takahashi, T. Non-NMDA glutamate receptor occupancy and open probability at a rat cerebellar synapse with single and multiple release sites. J. Physiol. 494, 231–250 (1996).
    Google Scholar
27. Ferking, M. & Wilson, M. Saturation of postsynaptic receptors at central synapses? Curr. Opin. Neurobiol. 6, 395–403 (1996).
    Google Scholar
28. Liao, D., Hessler, N. A. & Malinow, R. Activation of postsynaptically silent synapses during pairing-induced LTP in CA1 region of hippocampal slice. Nature 375, 400–404 (1995).
    Article ADS CAS Google Scholar
29. Isaac, J. T. R., Nicoll, R. A. & Malenka, R. C. Evidence for silent synapses: implications for the expression of LTP. Neuron 15, 427–434 (1995).
    Google Scholar
30. Durand, G. M., Kovalchuk, Y. & Konnerth, A. Long-term potentiation and functional synapse induction in developing hippocampus. Nature 381, 71–75 (1996).
    Article ADS CAS Google Scholar

Download references