The promises and perils of p53 (original) (raw)

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• Published: 26 August 2009

Stem cells

Nature volume 460, pages 1085–1086 (2009)Cite this article

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Five studies show that disabling p53, an essential tumour-suppressor protein, improves the efficiency of stem-cell production. Are these results a 'heads up' that cancer cells and stem cells are disturbingly similar?

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Figure 1: Overlapping mechanisms control iPS-cell and cancer-cell production.

Notes

1. *This article and the papers concerned1,2,3,4,5 were were previously published online.

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Authors and Affiliations

1. Valery Krizhanovsky and Scott W. Lowe are in the Cold Spring Harbor Laboratory and Howard Hughes Medical Institute, Cold Spring Harbor, New York 11724, USA.,
   Valery Krizhanovsky & Scott W. Lowe

Authors

1. Valery Krizhanovsky
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2. Scott W. Lowe
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Krizhanovsky, V., Lowe, S. The promises and perils of p53.Nature 460, 1085–1086 (2009). https://doi.org/10.1038/4601085a

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• Published: 26 August 2009
• Issue Date: 27 August 2009
• DOI: https://doi.org/10.1038/4601085a

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