Learning enhances adult neurogenesis in the hippocampal formation (original) (raw)

References

  1. Milner, B. Disorders of learning and memory after temporal lobe lesions in man. Clin. Neurosurg. 19, 421–446 (1972).
    Article CAS Google Scholar
  2. Squire, L. R. The neuropsychology of human memory. Annu. Rev. Neurosci. 5, 241–273 (1982).
    Article CAS Google Scholar
  3. Barnea, A. & Nottebohm, F. Seasonal recruitment of hippocampal neurons in adult free-ranging black-capped chickadees. Proc. Natl. Acad. Sci. USA 8, 11217–11221 (1994).
    Article Google Scholar
  4. Bayer, S. A. Changes in the total number of dentate granule cells in juvenile and adult rats: a correlated volumetric and 3H-thymidine autoradiographic study. Exp. Brain. Res. 46, 315– 323 (1982).
    Article CAS Google Scholar
  5. Cameron, H. A., Woolley, C. S., McEwen, B. S. & Gould, E. Differentiation of newly born neurons and glia in the dentate gyrus of the adult rat. Neuroscience 56, 337– 344 (1993).
    Article CAS Google Scholar
  6. Kempermann, G., Kuhn, H. G. & Gage, F. H. More hippocampal neurons in adult mice living in an enriched environment. Nature 386, 493– 495 (1997).
    Article CAS Google Scholar
  7. Gould, E., McEwen, B. S., Tanapat, P., Galea, L. A. M. & Fuchs, E. Neurogenesis in the dentate gyrus of the adult tree shrew is regulated by psychosocial stress and NMDA receptor activation. J. Neurosci. 17, 2492– 2498 (1997).
    Article CAS Google Scholar
  8. Gould, E., Tanapat, P., McEwen, B. S., Flugge, G. & Fuchs, E. Proliferation of granule cell precursors in the dentate gyrus of adult monkeys is diminished by stress. Proc. Natl. Acad. Sci. USA 95, 3168– 3171 (1998).
    Article CAS Google Scholar
  9. Solomon, P. R., Vander Schaaf, E. R., Weisz, D. J. & Thompson, R. F. Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response. Neuroscience 100, 729–744 (1986).
    CAS Google Scholar
  10. Moyer, J. R., Deyo, R. A. & Disterhoft, J. F. Hippocampectomy disrupts trace eye-blink conditioning in rabbits. Behav. Neurosci., 104, 243– 252 (1990).
    Article Google Scholar
  11. Weiss, C., Bouwmeester, H., Power, J. & Disterhoft, J. F. Hippocampal lesions prevent trace eyeblink conditioning in the freely moving rat. Behav. Brain Res. (in press).
  12. Clark, R. E. & Squire, L. R . Classical conditioning and brain systems: the role of awareness. Science 280, 77–81 (1998).
    Article CAS Google Scholar
  13. Morris, R. G. M., Garrud, P., Rawlins, J. N. P. & O'Keefe, J. Place navigation is impaired in rats with hippocampal lesions. Nature, 297, 681–683 ( 1982).
    Article CAS Google Scholar
  14. Kuhn, H. G., Dickinson-Anson, H. & Gage, F. H. Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation. J. Neurosci. 16, 2027–2033 ( 1996).
    Article CAS Google Scholar
  15. Gould, E., Woolley, C. S. & McEwen, B. S. Short-term glucocorticoid manipulations affect neuronal morphology and survival in the adult dentate gyrus. Neuroscience 37, 367–375 ( 1990).
    Article CAS Google Scholar
  16. Weisz, D., Clark, G. A. & Thompson, R. F. Increased responsivity of dentate granule cells during nictitating membrane response conditioning in the rabbit. Behav. Brain Res. 12, 145–154 ( 1984).
    Article CAS Google Scholar
  17. Shapiro, M. L., Tanila, H. & Eichenbaum, H. Cues that hippocampal place cells encode: dynamic and hierarchical representation of local and distal stimuli. Hippocampus 7, 624–642 ( 1997).
    Article CAS Google Scholar
  18. Gould, E., Cameron, H. A., Daniels, D. C., Woolley, C. S. & McEwen, B. S. Adrenal hormones suppress cell division in the adult rat dentate gyrus. J. Neurosci. 12, 3642–3650 (1992).
    Article CAS Google Scholar
  19. Cameron, H. A., Tanapat, P. & Gould, E. Adrenal steroids and N-methyl-D-aspartate receptor activation regulate neurogenesis in the dentate gyrus of adult rats through a common pathway. Neuroscience 82, 349– 354 (1998).
    Article CAS Google Scholar
  20. Moghaddam, B. & Bolinao, M. L., Stein-Behrens, B. & Sapolsky, R. Glucocorticoids mediate the stress-induced extracellular accumulation of glutamate. Brain Res. 655, 251–254 (1994).
    Article CAS Google Scholar
  21. Cameron, H. A. & Gould, E. Distinct populations of cells in the adult dentate gyrus undergo mitosis or apoptosis in response to adrenalectomy. J. Comp. Neurol. 369, 56–63 (1996).
    Article CAS Google Scholar
  22. Krugers, H. J. et al. Exposure to chronic psychosocial stress and corticosterone in the rat: effects on spatial discrimination learning and hippocampal protein kinase Cgamma immunoreactivity. Hippocampus 7, 427–436 (1997).
    Article CAS Google Scholar
  23. Bodnoff, S. R. et al. Enduring effects of chronic corticosterone treatment on spatial learning, synaptic plasticity, and hippocampal neuropathology in young and mid-aged rats. J. Neurosci. 15, 61– 69 (1995).
    Article CAS Google Scholar
  24. Wallenstein, G. V., Eichenbaum, H. & Hasselmo, M. E. The hippocampus as an associator of discontiguous events. Trends Neurosci. 21, 317– 323 (1998).
    Article CAS Google Scholar
  25. Squire, L. R. & Zola, S. M. Amnesia, memory and brain systems. Phil. Trans. R. Soc. Lond. B 352,1663– 1673 (1997).
    Article CAS Google Scholar
  26. Shors, T. J. & Mathew, P. R. NMDA receptor antagonism in the lateral/basolateral but not central nucleus of the amygdala prevents the induction of facilitated learning in response to stress. Learn. Mem. 5, 220–225 (1998).
    CAS PubMed PubMed Central Google Scholar
  27. Beylin, A. V. & Shors, T. J. Stress enhances excitatory trace eyeblink conditioning and opposes acquisition of inhibitory conditioning. Behav. Neurosci. 112, 1327– 1338 (1998).
    Article CAS Google Scholar
  28. Schmaltz, L. W. & Theios, J. Acquisition and extinction of a classically conditioned response in hippocampectomized rabbits. J. Comp. Physiol. Psychol. 79, 328– 333 (1972).
    Article CAS Google Scholar
  29. Markowska, A. L., Long, J. M., Johnson, C. T. & Olton, D. S. Variable-interval probe test as a tool for repeated measurements of spatial memory in the water maze. Behav. Neurosci. 107, 627–632 (1993).
    Article CAS Google Scholar
  30. McCormick, C. M., McNamara, M., Mukhopadhyay, S. & Kelsey, J. E. Acute corticosterone replacement reinstates performance on spatial and nonspatial memory tasks 3 months after adrenalectomy despite degeneration in the dentate gyrus. Behav. Neurosci. 111, 518– 531 (1997).
    Article CAS Google Scholar
  31. Minturn, J. E., Geschwind, D. H., Fryer, H. J. & Hockfield, S. Early postmitotic neurons transiently express TOAD-64, a neural specific protein. J. Comp. Neurol. 355, 369– 379 (1995).
    Article CAS Google Scholar
  32. West, M. J., Slomianka, L. & Gundersen, H. J. G. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rev. 231, 482– 497 (1991).
    Article CAS Google Scholar
  33. Gundersen, H. J. G. et al. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96 , 379–394 (1988).
    Article CAS Google Scholar
  34. Van Praag, H., Kempermann, G. & Gage, F. H. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat. Neurosci. 2, 266–270 (1999).
    Article CAS Google Scholar

Download references