In vivo magnetic resonance imaging of transgene expression (original) (raw)
References
Fukumura, D. et al. Tumor induction of VEGF promoter activity in stromal cells . Cell94, 715–725 (1998). ArticleCAS Google Scholar
Contag, P.R., Olomu, I.N., Stevenson, D.K. & Contag, C.H. Bioluminescent indicators in living mammals. Nature Med.4, 245–247 (1998). ArticleCAS Google Scholar
Weissleder, R., Tung, C.H., Mahmood, U. & Bogdanov, A. In vivo imaging of tumors with protease activated near-infrared fluorescent probes . Nature Biotechnol. 17, 375– 378 (1999). ArticleCAS Google Scholar
Tjuvajev, J., Finn, R. & Watanabe, K. Noninvasive imaging of herpes virus thymidine kinase gene transfer and expression: A potential method for monitoring clinical gene therapy. Cancer Res.56, 4087– 4095 (1996). CASPubMed Google Scholar
Gambhir, S.S. et al. Imaging adenoviral-directed reporter gene expression in living animals with positron emission tomography [In Process Citation]. Proc. Natl. Acad. Sci. USA96, 2333– 2338 (1999). ArticleCAS Google Scholar
Johnson, G.A. et al. Histology by magnetic resonance microscopy. Magn. Reson. Quart.9, 1–30 ( 1993). CAS Google Scholar
Smith, B., Johnson, G., Groman, E. & Linney, E. Magnetic resonance microscopy of mouse embryos. Proc. Natl. Acad. Sci. USA91, 3530–3533 (1994). ArticleCAS Google Scholar
Jacobs, R. & Fraser, S. Magnetic resonance microscopy of embryonic cell lineages and movements. Science263, 681–684 (1994). ArticleCAS Google Scholar
Moore, A., Basilion, J.P., Chiocca, A. & Weissleder, R. Measuring transferrin receptor gene expression by NMR imaging. Biochem. Biophys. Acta1402, 239–249 (1998). ArticleCAS Google Scholar
Casey, J. et al. Iron responsive elements: Regulatory RNA sequences that control mRNA levels and translation. Science8, 3693–3699 (1988). Google Scholar
Basilion, J.P. et al. Overexpression of iron-responsive element-binding protein and its analytical characterization as the RNA-binding form, devoid of an iron-sulfur cluster. Arch. Biochem. Biophys.311, 517–522 (1994). ArticleCAS Google Scholar
Shen, T., Weissleder, R., Papisov, M., Bogdanov, A. & Brady, T. Monocrystalline iron oxide nanocompounds (MION): Physicochemical properties. Magn. Reson. Med.29, 599–604 (1993). ArticleCAS Google Scholar
Enochs, W.S., Harsh, G., Hochberg, F. & Weissleder, R. Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent. J. Magn. Reson. Imag.9, 228–232 (1999). ArticleCAS Google Scholar
Josephson, L., Tung, C.H., Moore, A. & Weissleder, R. High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates . Bioconjug. Chem.10, 186– 191 (1999). ArticleCAS Google Scholar
Casey, J., Koellert, D., Ramin, V., Klausner, R. & Harford, J. Iron regulation of transferrin receptor mRNA levels requires iron-responsive elements and a rapid turnover determinant in the 3′ untranslated region of the mRNA. EMBO J.8 , 3693–3699 (1989). ArticleCAS Google Scholar
Basilion, J.P. et al. Selective killing of cancer cells based on loss of heterozygosity and normal variation in the human genome: A new paradigm for anticancer drug therapy. Molec. Pharmacol.56, 359– 369 (1999). ArticleCAS Google Scholar
Schoepf, U., Marecos, E.M., Melder, R.J., Jain, R.K. & Weissleder, R. Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. Biotechniques24, 642–646, 648–651 (1998). Article Google Scholar
Muldoon, L.L. et al. Comparison of intracerebral inoculation and osmotic blood–brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Am. J. Pathol.147, 1840–1851 (1995). CASPubMedPubMed Central Google Scholar
Weissleder, R., Cheng, H., Bogdanova, A., Bogdanov, A., Jr. Magnetically labeled cells can be detected by MR imaging. J. Magn. Reson. Imag.7, 258–263 ( 1997). ArticleCAS Google Scholar