Advances in schizophrenia (original) (raw)

• Kraepelin, E. Dementia Praecox and Paraphrenia. (Huntington, New York, 1919).
• Bleuler, M. Demential Praecox or the Group of Schizophrenias. (International Universities Press, New York, 1950).
  Google Scholar
• Abi-Dargham, A. et al. Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort. Am. J. Psychiatry 155, 761–767 (1998).
  Article CAS Google Scholar
• Breier, A. et al. Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method. Proc. Natl. Acad. Sci. USA 94, 2569–2574 (1997).
  Article CAS Google Scholar
• Tamminga, C.A. Schizophrenia and glutamatergic transmission. Crit. Rev. Neurobiol. 12, 21–36 (1998).
  Article CAS Google Scholar
• Smiley, J.F., Levey, A.I., Ciliax, B.J. & Goldman-Rakic, P.S. D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines. Proc. Natl. Acad. Sci. USA 91, 5720–5724 (1994).
  Article CAS Google Scholar
• Bergson, C. et al. Regional, cellular, and subcellular variations in the distribution of D1 and D5 dopamine receptors in primate brain. J. Neurosci. 15, 7821–7836 (1995).
  Article CAS Google Scholar
• Otani, S., Auclair, N., Desce, J.M., Roisin, M.P. & Crepel, F. Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases. J. Neurosci. 19, 9788–9802 (1999).
  Article CAS Google Scholar
• Seamans, J.K., Durstewitz, D., Christie, B.R., Stevens, C.F. & Sejnowski, T.J. Dopamine D1/D5 receptor modulation of excitatory synaptic inputs to layer V prefrontal cortex neurons. Proc. Natl. Acad. Sci. USA 98, 301–306 (2001).
  Article CAS Google Scholar
• Gao, W.J., Krimer, L.S. & Goldman-Rakic, P.S. Presynaptic regulation of recurrent excitation by D1 receptors in prefrontal circuits. Proc. Natl. Acad. Sci. USA 98, 295–300 (2001).
  Article CAS Google Scholar
• Benes, F.M. Emerging principles of altered neural circuitry in schizophrenia. Brain Res. Brain Res. Rev. 31, 251–269 (2000).
  Article CAS Google Scholar
• Bogerts, B. The neuropathology of schizophrenic diseases: historical aspects and present knowledge. Eur. Arch. Psychiatry Clin. Neurosci. 249 (Suppl. 4), 2–13 (1999).
  Article Google Scholar
• Sanfilipo, M. et al. Volumetric measure of the frontal and temporal lobe regions in schizophrenia: relationship to negative symptoms. Arch. Gen. Psychiatry 57, 471–480 (2000).
  Article CAS Google Scholar
• Selemon, L.D. & Goldman-Rakic, P.S. The reduced neuropil hypothesis: a circuit based model of schizophrenia. Biol. Psychiatry 45, 17–25 (1999).
  Article CAS Google Scholar
• Glantz, L.A. & Lewis, D.A. Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia. Arch. Gen. Psychiatry 57, 65–73 (2000).
  Article CAS Google Scholar
• Lidow, M.S. et al. Antipsychotic treatment induces alterations in dendrite- and spine-associated proteins in dopamine-rich areas of the primate cerebral cortex. Biol. Psychiatry 49, 1–12 (2001).
  Article CAS Google Scholar
• Mirnics, K., Middleton, F.A., Marquez, A., Lewis, D.A. & Levitt, P. Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex. Neuron 28, 53–67 (2000).
  Article CAS Google Scholar
• Mednick, S.A., Machon, R.A., Huttunen, M.O. & Bonett, D. Adult schizophrenia following prenatal exposure to an influenza epidemic. Arch. Gen. Psychiatry 45, 189–192 (1988).
  Article CAS Google Scholar
• Karlsson, H. et al. Retroviral RNA identified in the cerebrospinal fluids and brains of individuals with schizophrenia. Proc. Natl. Acad. Sci. USA 98, 4634–4639 (2001).
  Article CAS Google Scholar
• Kendler, K.S. & Diehl, S.R. Schizophrenia: Genetics. in Comprehensive Textbook of Psychiatry. Vol. VI (eds. Kaplan, H.I. & Sadock, B.J.) 942–957 (Williams and Wilkins, Baltimore, Maryland, 1995).
  Google Scholar
• Cannon, T.D., Kaprio, J., Lonnqvist, J., Huttunen, M. & Koskenvuo, M. The genetic epidemiology of schizophrenia in a Finnish twin cohort. A population-based modeling study. Arch. Gen. Psychiatry 55, 67–74 (1998).
  Article CAS Google Scholar
• Tsuang, M.T., Stone, W.S. & Faraone, S.V. Schizophrenia: a review of genetic studies. Harv. Rev. Psychiatry 7, 185–207 (1999).
  Article CAS Google Scholar
• Pulver, A.E. Search for schizophrenia susceptibility genes. Biol. Psychiatry 47, 221–230 (2000).
  Article CAS Google Scholar
• Thaker, G.K. Defining the schizophrenia phenotype. Current Psychiatry Reports 2, 398–403 (2000).
  Article CAS Google Scholar
• Carpenter, W.T. Jr, Heinrichs, D.W. & Wagman, A.M. Deficit and nondeficit forms of schizophrenia: The concept. Am. J. Psychiatry 145, 578–583 (1988).
  Article Google Scholar
• Fenton, W.S. & McGlashan, T.H. Antecedents, symptom progression, and long-term outcome of the deficit syndrome in schizophrenia. Am. J. Psychiatry 151, 351–356 (1994).
  Article CAS Google Scholar
• Waltrip, R.W. et al. Borna disease virus antibodies and the deficit syndrome of schizophrenia. Schizophr. Res. 23, 253–257 (1997).
  Article Google Scholar
• Kirkpatrick, B., Buchanan, R.W., Ross, D.E. & Carpenter, W.T.J. A separate disease within the syndrome of schizophrenia. Arch. Gen. Psychiatry 58, 165–171 (2001).
  Article CAS Google Scholar
• Ross, D.E. et al. Sibling correlation of deficit syndrome in the Irish study of high-density schizophrenia families. Am. J. Psychiatry 157, 1071–1076 (2000).
  Article CAS Google Scholar
• Tamminga, C.A. et al. Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. Arch. Gen. Psychiatry 49, 522–530 (1992).
  Article CAS Google Scholar
• Carpenter, W.T. Jr, Buchanan, R.W., Kirkpatrick, B., Tamminga, C.A. & Wood, F. Strong inference, theory testing, and the neuroanatomy of schizophrenia. Arch. Gen. Psychiatry 50, 825–831 (1993).
  Article Google Scholar
• Holzman, P.S., Proctor, L.R. & Hughes, D.W. Eye-tracking patterns in schizophrenia. Science 181, 179–181 (1973).
  Article CAS Google Scholar
• Arolt, V. et al. Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease. Am. J Med. Genet. 67, 564–579 (1996).
  Article CAS Google Scholar
• Cannon, T.D. et al. Neuropsychological functioning in siblings discordant for schizophrenia and healthy volunteers. Arch. Gen. Psychiatry 51, 651–661 (1994).
  Article CAS Google Scholar
• Callicott, J.H. et al. Hippocampal N-acetyl aspartate in unaffected siblings of patients with schizophrenia: a possible intermediate neurobiological phenotype. Biol. Psychiatry 44, 941–950 (1998).
  Article CAS Google Scholar
• Freedman, R., Adler, L.E. & Leonard, S. Alternative phenotypes for the complex genetics of schizophrenia. Biol. Psychiatry 45, 551–558 (1999).
  Article CAS Google Scholar
• Freedman, R. et al. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proc. Natl. Acad. Sci. USA 94, 587–592 (1997).
  Article CAS Google Scholar
• Freedman, R. & Leonard, S. Schizophrenia and 15q14. Am. J. Med. Genet. (in the press).
• Carlsson, A. & Lindquist, M. Effect of chlorpromazine and haloperidol of formation of 3- methoxytyramine and normetanephrine in mouse brain. Acta Pharmacol. Toxicol. 140–144 (1963).
• Kane, J., Honigfeld, G., Singer, J. & Meltzer, H. Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine. Arch. Gen. Psychiatry 45, 789–796 (1988).
  Article CAS Google Scholar
• Goff, D.C., Tsai, G., Manoach, D.S. & Coyle, J.T. Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia. Am. J. Psychiatry 152, 1213–1215 (1995).
  Article CAS Google Scholar
• Heresco-Levy, U. et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch. Gen. Psychiatry 56, 29–36 (1999).
  Article CAS Google Scholar
• Mirnics, K., Middleton, F.A., Stanwood, G.D., Lewis, D.A. & Levitt, P. Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia. Mol. Psychiatry, 293–301 (2001).
• Brzustowicz, L.M., Hodgkinson, K.A., Chow, E.W., Honer, W.G. & Bassett, A.S. Location of a major susceptibility locus for familial schizophrenia on chromosome 1q21-q22. Science 288, 678–682 (2000).
  Article CAS Google Scholar
• Sherrington, R. et al. Localization of a susceptibility locus for schizophrenia on chromosome 5. Nature 336, 164–167 (1988).
  Article CAS Google Scholar
• Arolt, V. et al. Eye tracking dysfunction is a putative phenotypic susceptibility marker of schizophrenia and maps to a locus on chromosome 6p in families with multiple occurrence of the disease. Am. J. Med. Genet. 67, 564–579 (1996).
  Article CAS Google Scholar
• Pulver, A.E. et al. Genetic heterogeneity in schizophrenia: stratification of genome scan data using co-segregating related phenotypes. Mol. Psychiatry 5, 650–653 (2000).
  Article CAS Google Scholar
• Detera-Wadleigh, S.D. et al. A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2. Proc. Natl. Acad. Sci. USA 96, 5604–5609 (1999).
  Article CAS Google Scholar
• Myles-Worsley, M. et al. Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families. Am. J. Med. Genet. 88, 544–550 (1999).
  Article CAS Google Scholar
• Scambler, P.J. et al. Velo-cardio-facial syndrome associated with chromosome 22 deletions encompassing the DiGeorge locus. Lancet 339, 1138–1139 (1992).
  Article CAS Google Scholar
• Kelsoe, J.R. et al. A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. Proc. Natl. Acad. Sci. USA 98, 585–590 (2001).
  Article CAS Google Scholar
• Baron, M. Genetics of schizophrenia and the new millennium: progress and pitfalls. Am. J. Hum. Genet. 68, 299–312 (2001).
  Article CAS Google Scholar
• Egan, M.F. et al. Effect of COMT val108/158met genotype on frontal lobe function and risk for schizophrenia. Proc. Natl. Acad. Sci. USA (in the press).
• Berrettini, W.H. Are schizophrenic and bipolar disorders related? A review of family and molecular studies. Biol. Psychiatry 48, 531–538 (2000).
  Article CAS Google Scholar