The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries (original) (raw)
References
Grüneberg, H. Genetical studies on the skeleton of the mouse: XXIX. Genet. Res.2, 384–393 (1961). Article Google Scholar
Dunwoodie, S.L., Henrique, D., Harrison, S.M. & Beddington, R.S.P. Mouse DII3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo. Development124, 3065 –3076 (1997). CAS Google Scholar
Conlon, R.A., Reaume, A.G. & Rossant, J. Notch1 is required for the coordinate segmentation of somites. Development121, 1533–1545 (1995). CAS Google Scholar
Wong, P.C. et al. Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm. Nature387, 288– 292 (1997). ArticleCAS Google Scholar
Shen, J. et al. Skeletal and CNS defects in Presenilin-1 deficient mice. Cell89, 629–639 ( 1997). ArticleCAS Google Scholar
Oka, C. et al. Disruption of the mouse RBP-jχ gene results in early embryonic death. Development121, 3291–3301 (1995). CAS Google Scholar
Bettenhausen, B., de Angelis, M.H., Simon, D., Guenet, J.L. & Gossler, A. Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta. Development121, 2407–2418 (1995). CAS Google Scholar
de Angelis, M.H., McIntyre, J.I. & Gossler, A. Maintenance of somite borders in mice requires the Delta homologue Dll1. Nature386, 717–721 (1997). Article Google Scholar
Jen, W.-C., Wettstein, D., Turner, D., Chitnis, A. & Kintner, C. The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embyros. Development124, 1169–1178 (1997). CAS Google Scholar
Vassin, H., Bremer, K.A., Knust, E. & Campos-Ortega, J.A. The neurogenic gene Delta of Drosophila melanogaster is expressed in neurogenic territories and encodes a putative transmembrane protein with EGF-like repeats . EMBO J.6, 3431–3440 (1987). Article Google Scholar
Keynes, R.J. & Stern, C.D. Mechanisms of vertebrate segmentation . Development103, 413– 29 (1988). CAS Google Scholar
Cohen, B. et al. Fringe boundaries coincide with _Notch_-dependent patterning centres in mammals and alter _Notch_-dependent development in Drosophila. Nature Genet.16, 283–288 (1997). ArticleCAS Google Scholar
Johnston, S.H. et al. A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development124, 2245–2254 (1997). CAS Google Scholar
Deutsch, U., Dressler, G.R. & Gruss, P. Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development. Cell53 , 617–625 (1988). ArticleCAS Google Scholar
Candia, A.F. et al. Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos . Development116, 1123– 1136 (1992). CAS Google Scholar
Serbedzija, G.N., Fraser, S.E. & Bronner-Fraser, M. Pathways of trunk neural crest cell migration in the mouse embryos as revealed by vital dye labelling. Development108, 605–612 (1990). CAS Google Scholar
Herrmann, B.G. & Kispert, A. The T genes in embryogenesis . Trends Genet.10, 280– 286 (1994). ArticleCAS Google Scholar
Panin, V.N., Papayannopoulos, V., Wilson, R. & Irvine, K.D. Fringe modulates _Notch_-ligand interactions. Nature387, 908–912 (1997). ArticleCAS Google Scholar
Williams, R., Lendahl, U. & Lardelli, M. Complementary and combinatorial patterns of Notch gene family expression during early mouse development. Mech. Dev.53, 357–368 (1995). ArticleCAS Google Scholar
Dietrich, W. et al. A genetic map of the mouse suitable for typing intraspecific crosses. Genetics131, 423–447 ( 1992). CAS Google Scholar
Kusumi, K., Smith, J.S., Segre, J.A., Koos, D.S. & Lander, E.S. Construction of a large-insert yeast artificial chromosome library of the mouse genome. Mamm. Genome4, 391–392 (1993). ArticleCAS Google Scholar
Haldi, M.L. et al. A comprehensive large-insert yeast artificial chromosome library for physical mapping of the mouse genome. Mamm. Genome7, 767–769 (1996). ArticleCAS Google Scholar
Larin, Z., Monaco, A.P. & Lehrach, H. Yeast artificial chromosome libraries containing large inserts from mouse and human DNA. Proc. Natl Acad. Sci. USA88, 4123–4127 (1991). ArticleCAS Google Scholar
Segre, J.A., Nemhauser, J.L., Taylor, B.A., Nadeau, J.H. & Lander, E.S. Positional cloning of the nude locus: Genetic, physical, and transcription maps of the region and mutations in the mouse and rat. Genomics28, 549– 559 (1995). ArticleCAS Google Scholar
Hamilton, B.A. et al. The vibrator mutation causes neurodegeneration via reduced expression of PITP*: Positional complementation cloning and extragenic suppression . Neuron18, 711–722 (1997). ArticleCAS Google Scholar
McLeod, M.J. Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratol.22, 299–301 (1980).
Kaufman, M.H. The Atlas of Mouse Development (Academic Press Limited, London, 1992). Google Scholar
Wilkinson, D.G. In Situ Hybridization: A Practical Approach (Oxford University Press, Oxford, 1992). Google Scholar
Fahrner, K., Hogan, B.L. & Flavell, R.A. Transcription of H-2 and Qa genes in embryonic and adult mice. EMBO J.6, 1265– 1271 (1987). ArticleCAS Google Scholar
Sambrook, J., Fritsch, E.F. & Maniatis, T. Molecular Cloning: A Laboratory Manual (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1989 ). Google Scholar