Administration of omega-3 fatty acids and Raloxifene to women at high risk of breast cancer: interim feasibility and biomarkers analysis from a clinical trial (original) (raw)

References

  1. Signori C, El-Bayoumy K, Russo J, Thompson HJ, Richie JP, Hartman TJ et al. Chemoprevention of breast cancer by fish oil in preclinical models: trials and tribulations. Cancer Res 2011; 71: 6091–6096.
    Article CAS Google Scholar
  2. Manni A, Xu H, Washington S, Aliaga C, Cooper T, Richie JP et al. The impact of fish oil on the chemopreventive efficacy of tamoxifen against development of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Cancer Prev Res 2010; 3: 322–330.
    Article CAS Google Scholar
  3. Manni A, Richie JP, Xu H, Washington S, Aliaga C, Cooper TK et al. Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Int J Oncol 2011; 39: 1153–1164.
    CAS PubMed Google Scholar
  4. Manni A, Xu H, Washington S, Aliaga C, Das A, Cooper T et al. The effects of Tamoxifen and fish oil on mammary carcinogenesis in polyoma middle T transgenic mice. Horm Cancer 2011; 2: 249–259.
    Article CAS Google Scholar
  5. Boyd NF, Martin LJ, Rommens JM, Paterson AD, Minkin S, Yaffe MJ et al. Mammographic density: a heritable risk factor for breast cancer. Methods Mol Biol 2009; 472: 343–360.
    Article Google Scholar
  6. Subar AF, Thompson FE, Kipnis V, Midthune D, Hurwitz P, McNutt S et al. Comparative validation of the Block, Willett, and National Cancer Institute food frequency questionnaires: the Eating at America's Table Study. Am J Epidemiol 2001; 154: 1089–1099.
    Article CAS Google Scholar
  7. Miller PE, Lazarus P, Lesko SM, Muscat JE, Harper G, Cross AJ et al. Diet index-based and empirically derived dietary patterns are associated with colorectal cancer risk. J Nutr 2010; 140: 1267–1273.
    Article CAS Google Scholar
  8. Craig CL, Marshall AL, Sjostrom M, Bauman AE, Booth ML, Ainsworth BE et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 2003; 35: 1381–1395.
    Article Google Scholar
  9. Slot C . Plasma creatinine determination. A new and specific Jaffe reaction method. Scand J Clin Lab Invest 1965; 17: 381–387.
    Article CAS Google Scholar
  10. Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, Cronin WM et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 1998; 90: 1371–1388.
    Article CAS Google Scholar
  11. Vogel VG, Costantino JP, Wickerham DL, Cronin WM, Cecchini RS, Atkins JN et al. Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: the NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial. JAMA 2006; 295: 2727–2741.
    Article CAS Google Scholar
  12. Ropka ME, Keim J, Philbrick JT . Patient decisions about breast cancer chemoprevention: a systematic review and meta-analysis. J Clin Oncol 2010; 28: 3090–3095.
    Article Google Scholar
  13. Waters EA, Cronin KA, Graubard BI, Han PK, Freedman AN . Prevalence of tamoxifen use for breast cancer chemoprevention among U.S. women. Cancer Epidemiol Biomarkers Prev 2010; 19: 443–446.
    Article CAS Google Scholar
  14. Ruxton CH, Reed SC, Simpson MJ, Millington KJ . The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence. J Hum Nutr Diet 2007; 20: 275–285.
    Article CAS Google Scholar
  15. Yee LD, Lester JL, Cole RM, Richardson JR, Hsu JC, Li Y et al. Omega-3 fatty acid supplements in women at high risk of breast cancer have dose-dependent effects on breast adipose tissue fatty acid composition. Am J Clin Nutr 2010; 91: 1185–1194.
    Article CAS Google Scholar
  16. Harris WS . n-3 fatty acids and serum lipoproteins: human studies. Am J Clin Nutr 1997; 65 (5 Suppl), 1645S–1654SS.
    Article CAS Google Scholar
  17. Skulas-Ray AC, Kris-Etherton PM, Harris WS, Vanden Heuvel JP, Wagner PR, West SG . Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia. Am J Clin Nutr 2011; 93: 243–252.
    Article CAS Google Scholar
  18. Lee AV . YD. Role of the IGF System. In Breast Cancer Proliferation and Progression. Manni A (ed)., Humana Press, Inc.: Totowa, NJ, 1999.
  19. Renehan AG, Zwahlen M, Minder C, O’Dwyer ST, Shalet SM, Egger M . Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet 2004; 363: 1346–1353.
    Article CAS Google Scholar
  20. Hankinson SE, Willett WC, Colditz GA, Hunter DJ, Michaud DS, Deroo B et al. Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet 1998; 351: 1393–1396.
    Article CAS Google Scholar
  21. Torrisi R, Baglietto L, Johansson H, Veronesi G, Bonanni B, Guerrieri-Gonzaga A et al. Effect of raloxifene on IGF-I and IGFBP-3 in postmenopausal women with breast cancer. Br J Cancer 2001; 85: 1838–1841.
    Article CAS Google Scholar
  22. Oleksik AM, Duong T, Pliester N, Asma G, Popp-Snijders C, Lips P . Effects of the selective estrogen receptor modulator, raloxifene, on the somatotropic axis and insulin-glucose homeostasis. J Clin Endocrinol Metab 2001; 86: 2763–2768.
    Article CAS Google Scholar
  23. Eliassen AH, Missmer SA, Tworoger SS, Hankinson SE . Circulating 2-hydroxy- and 16alpha-hydroxy estrone levels and risk of breast cancer among postmenopausal women. Cancer Epidemiol Biomarkers Prev 2008; 17: 2029–2035.
    Article CAS Google Scholar
  24. Osborne MPKR, Hershcopf RJ, Bradlow HL, Kourides IA, Williams WR, Rosen PP et al. Omega-3 fatty acids: modulation of estrogen metabolism and potential for breast cancer prevention. Cancer Investigation 1988; 6: 629–631.
    Article Google Scholar
  25. Rossner P, Gammon MD, Terry MB, Agrawal M, Zhang FF, Teitelbaum SL et al. Relationship between urinary 15-F2t-isoprostane and 8-oxodeoxyguanosine levels and breast cancer risk. Cancer Epidemiol Biomarkers Prev 2006; 15: 639–644.
    Article CAS Google Scholar

Download references