Role of orexin-A in the ventrolateral preoptic area on components of total energy expenditure (original) (raw)
de Lecea L, Kilduff TS, Peyron C, Gao X, Foye PE, Danielson PE et al. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc Natl Acad Sci USA 1998; 95: 322–327. ArticleCAS Google Scholar
Sakurai T, Amemiya A, Ishii M, Matsuzaki I, Chemelli RM, Tanaka H et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 1998; 92: 1–696. Article Google Scholar
Li J, Hu Z, de Lcea L . The hypocretins/orexins: integrators of multiple physiological functions. Br J Pharmacol 2014; 171: 332–350. ArticleCAS Google Scholar
Lin L, Faraco J, Li R, Kadotani H, Rogers W, Lin X et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell 1999; 98: 365–376. ArticleCAS Google Scholar
Chemelli RM, Willie JT, Sinton CM, Elmquist JK, Scammell T, Lee C et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 1999; 98: 437–451. ArticleCAS Google Scholar
Thannickal TC, Moore RY, Nienhuis R, Ramanathan L, Gulyani S, Aldrich M et al. Reduced number of hypocretin neurons in human narcolepsy. Neuron 2000; 27: 469–474. ArticleCAS Google Scholar
Nishino S, Ripley B, Overeem S, Lammers GJ, Mignot E . Hypocretin (orexin) deficiency in human narcolepsy. Lancet 2000; 355: 39–40. ArticleCAS Google Scholar
Hara J, Beuckmann CT, Nambu T, Willie JT, Chemelli RM, Sinton CM et al. Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron 2001; 30: 345–354. ArticleCAS Google Scholar
Hagan JJ, Leslie RA, Patel S, Evans ML, Wattam TA, Holmes S et al. Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc Natl Acad Sci USA 1999; 96: 10911–10916. ArticleCAS Google Scholar
Piper DC, Upton N, Smith MI, Hunter AJ . The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats. Eur J Neurosci 2000; 12: 726–730. ArticleCAS Google Scholar
Kotz CM, Teske JA, Billington CJ . Neuroregulation of nonexercise activity thermogenesis and obesity resistance. Am J Physiol Regul Integr Comp Physiol 2008; 294: R699–R710. ArticleCAS Google Scholar
Lubkin M, Stricker-Krongrad A . Independent feeding and metabolic actions of orexins in mice. Biochem Biophys Res Commun 1998; 253: 241–245. ArticleCAS Google Scholar
Sweet DC, Levine AS, Billington CJ, Kotz CM . Feeding response to central orexins. Brain Res 1999; 821: 535–538. ArticleCAS Google Scholar
Brisbare-Roch C, Dingemanse J, Koberstein R, Hoever P, Aissaoui H, Flores S et al. Promotion of sleep by targeting the orexin system in rats, dogs and humans. Nat Med 2007; 13: 150–155. ArticleCAS Google Scholar
Winrow CJ, Tanis KQ, Reiss DR, Rigby AM, Uslaner JM, Uebele VN et al. Orexin receptor antagonism prevents transcriptional and behavioral plasticity resulting from stimulant exposure. Neuropharmacology 2010; 58: 185–194. ArticleCAS Google Scholar
Mang GM, Dürst T, Bürki H, Imobersteg S, Abramowski D, Schuepbach E et al. The dual orexin receptor antagonist almorexant induces sleep and decreases orexin-induced locomotion by blocking orexin 2 receptors. Sleep 2012; 35: 1625–1635. Article Google Scholar
Sherin JE, Shiromani PJ, McCarley RW, Saper CB . Activation of ventrolateral preoptic neurons during sleep. Science 1996; 271: 216–219. ArticleCAS Google Scholar
Szymusiak R, Alam N, Steininger TL, McGinty D . Sleep-waking discharge patterns of ventrolateral preoptic/anterior hypothalamic neurons in rats. Brain Res 1998; 803: 178–188. ArticleCAS Google Scholar
Sakurai T, Nagata R, Yamanaka A, Kawamura H, Tsujino N, Muraki Y et al. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron 2005; 46: 297–308. ArticleCAS Google Scholar
Marcus JN, Aschkenasi CJ, Lee CE, Chemelli RM, Saper CB, Yanagisawa M et al. Differential expression of orexin receptors 1 and 2 in the rat brain. J Comp Neurol 2001; 435: 6–25. ArticleCAS Google Scholar
Mavanji V, Teske JA, Billington CJ, Kotz CM . Elevated sleep quality and orexin receptor mRNA in obesity-resistant rats. Int J Obes (Lond) 2010; 34: 1576–1588. ArticleCAS Google Scholar
Methippara MM, Alam MN, Szymusiak R, McGinty D . Effects of lateral preoptic area application of orexin-A on sleep–wakefulness. Neuroreport 2000; 11: 3423–3426. ArticleCAS Google Scholar
Levine JA, Eberhardt NL, Jensen MD . Role of nonexercise activity thermogenesis in resistance to fat gain in humans. Science 1999; 283: 212–214. ArticleCAS Google Scholar
Mavanji V, Perez-Leighton CE, Kotz CM, Billington CJ, Parthasarathy S, Sinton CM et al. Promotion of wakefulness and energy expenditure by orexin A in the ventrolateral preoptic area. Sleep 2015; 38: 1361–1370. Article Google Scholar
Paxinos G, Watson C, Pennisi M, Bregma Topple A . lambda and the interaural midpoint in stereotaxic surgery with rats of different sex, strain and weight. J Neurosci Methods 1985; 13: 139–143. ArticleCAS Google Scholar
O'Hare E, Cleary J, Weldon DT, Pomonis JD, Billington CJ, Levine AS . Intrahypothalamic discriminative stimulus effects of neuropeptide Y. Pharmacol Biochem Behav 1998; 59: 375–378. ArticleCAS Google Scholar
Teske JA, Billington CJ, Kotz CM . Mechanisms underlying obesity resistance associated with high spontaneous physical activity. Neuroscience 2014; 256: 91–100. ArticleCAS Google Scholar
Nicholson C . Diffusion from an injected volume of a substance in brain tissue with arbitrary volume fraction and tortuosity. Brain Res 1985; 333: 325–329. ArticleCAS Google Scholar
Kaiyala KJ, Morton GJ, Thaler JP, Meek TH, Tylee T, Ogimoto K et al. Acutely decreased thermoregulatory energy expenditure or decreased activity energy expenditure both acutely reduce food intake in mice. PLoS One 2012; 7: e41473. ArticleCAS Google Scholar
Weir JB . New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949; 109: 1–9. Article Google Scholar
Parrish JB, Teske JA . Acute partial sleep deprivation due to environmental noise increases weight gain by reducing energy expenditure in rodents. Obesity (Silver Spring, MD) 2017; 25: 141–146. Article Google Scholar
Teske JA, Billington CJ, Kuskowski MA, Kotz CM . Spontaneous physical activity protects against fat mass gain. Int J Obes (Lond) 2012; 36: 603–613. ArticleCAS Google Scholar
Kotz CM, Teske JA, Levine JA, Wang C . Feeding and activity induced by orexin A in the lateral hypothalamus in rats. Regul Pept 2002; 104: 27–32. ArticleCAS Google Scholar
Kotz C, Nixon J, Butterick T, Perez-Leighton C, Teske J, Billington C . Brain orexin promotes obesity resistance. Ann NY Acad Sci 2012; 1264: 72–86. ArticleCAS Google Scholar
Winrow CJ, Renger JJ . Discovery and development of orexin receptor antagonists as therapeutics for insomnia. Br J Pharmacol 2014; 171: 283–293. ArticleCAS Google Scholar
Huang ZL, Qu WM, Li WD, Mochizuki T, Eguchi N, Watanabe T et al. Arousal effect of orexin A depends on activation of the histaminergic system. Proc Natl Acad Sci USA 2001; 98: 9965–9970. ArticleCAS Google Scholar
Kiwaki K, Kotz CM, Wang C, Lanningham-Foster L, Levine JA, Orexin A . (hypocretin 1) injected into hypothalamic paraventricular nucleus and spontaneous physical activity in rats. Am J Physiol Endocrinol Metab 2004; 286: E551–E559. ArticleCAS Google Scholar
Novak CM, Kotz CM, Levine JA . Central orexin sensitivity, physical activity, and obesity in diet-induced obese and diet-resistant rats. Am J Physiol Endocrinol Metab 2006; 290: E396–E403. ArticleCAS Google Scholar
Yoshimichi G, Yoshimatsu H, Masaki T, Sakata T . Orexin-A regulates body temperature in coordination with arousal status. Exp Biol Med (Maywood) 2001; 226: 468–476. ArticleCAS Google Scholar
Tupone D, Madden CJ, Cano G, Morrison SF . An orexinergic projection from perifornical hypothalamus to raphe pallidus increases rat brown adipose tissue thermogenesis. J Neurosci 2011; 31: 15944–15955. ArticleCAS Google Scholar
Shirasaka T, Nakazato M, Matsukura S, Takasaki M, Kannan H . Sympathetic and cardiovascular actions of orexins in conscious rats. Am J Physiol 1999; 277 (Part 2): R1780–R1785. CASPubMed Google Scholar
Novak CM, Levine JA . Daily intraparaventricular orexin-A treatment induces weight loss in rats. Obesity (Silver Spring, MD) 2009; 17: 1493–1498. ArticleCAS Google Scholar
Herring WJ, Snyder E, Budd K, Hutzelmann J, Snavely D, Liu K et al. Orexin receptor antagonism for treatment of insomnia: a randomized clinical trial of suvorexant. Neurology 2012; 79: 2265–2274. ArticleCAS Google Scholar
Ramirez AD, Gotter AL, Fox SV, Tannenbaum PL, Yao L, Tye SJ et al. Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators. Front Neurosci 2013; 7: 254. Article Google Scholar
Ravussin E, Burnand B, Schutz Y, Jequier E . Twenty-four-hour energy expenditure and resting metabolic rate in obese, moderately obese, and control subjects. Am J Clin Nutr 1982; 35: 566–573. ArticleCAS Google Scholar
Yamanaka A, Tsujino N, Funahashi H, Honda K, Guan JL, Wang QP et al. Orexins activate histaminergic neurons via the orexin 2 receptor. Biochem Biophys Res Commun 2002; 290: 1237–1245. ArticleCAS Google Scholar
Takahashi K, Koyama Y, Kayama Y, Yamamoto M . Effects of orexin on the laterodorsal tegmental neurones. Psychiatry Clin Neurosci 2002; 56: 335–336. ArticleCAS Google Scholar
Brown RE, Sergeeva OA, Eriksson KS, Haas HL . Convergent excitation of dorsal raphe serotonin neurons by multiple arousal systems (orexin/hypocretin, histamine and noradrenaline). J Neurosci 2002; 22: 8850–8859. ArticleCAS Google Scholar
Hirota K, Kushikata T, Kudo M, Kudo T, Lambert DG, Matsuki A . Orexin A and B evoke noradrenaline release from rat cerebrocortical slices. Br J Pharmacol 2001; 134: 1461–1466. ArticleCAS Google Scholar
Fadel J, Pasumarthi R, Reznikov LR . Stimulation of cortical acetylcholine release by orexin A. Neuroscience 2005; 130: 541–547. ArticleCAS Google Scholar
Tao R, Ma Z, McKenna JT, Thakkar MM, Winston S, Strecker RE et al. Differential effect of orexins (hypocretins) on serotonin release in the dorsal and median raphe nuclei of freely behaving rats. Neuroscience 2006; 141: 1101–1105. ArticleCAS Google Scholar
Gallopin T, Fort P, Eggermann E, Cauli B, Luppi PH, Rossier J et al. Identification of sleep-promoting neurons in vitro. Nature 2000; 404: 992–995. ArticleCAS Google Scholar
Liu YW, Li J, Ye JH . Histamine regulates activities of neurons in the ventrolateral preoptic nucleus. J Physiol. 2010; 588 (Part 21): 4103–4116. ArticleCAS Google Scholar
Matsuo S, Jang IS, Nabekura J, Akaike N . Alpha 2-adrenoceptor-mediated presynaptic modulation of GABAergic transmission in mechanically dissociated rat ventrolateral preoptic neurons. J Neurophysiol 2003; 89: 1640–1648. ArticleCAS Google Scholar
Saper CB, Chou TC, Scammell TE . The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci 2001; 24: 726–731. ArticleCAS Google Scholar
Date Y, Ueta Y, Yamashita H, Yamaguchi H, Matsukura S, Kangawa K et al. Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc Natl Acad Sci USA 1999; 96: 748–753. ArticleCAS Google Scholar
Wang J, Osaka T, Inoue S . Energy expenditure by intracerebroventricular administration of orexin to anesthetized rats. Neurosci Lett 2001; 315: 49–52. ArticleCAS Google Scholar
Li A, Hindmarch CC, Nattie EE, Paton JF . Antagonism of orexin receptors significantly lowers blood pressure in spontaneously hypertensive rats. J Physiol 2013; 591: 4237–4248. ArticleCAS Google Scholar
Backberg M, Hervieu G, Wilson S, Meister B . Orexin receptor-1 (OX-R1) immunoreactivity in chemically identified neurons of the hypothalamus: focus on orexin targets involved in control of food and water intake. Eur J Neurosci 2002; 15: 315–328. Article Google Scholar
Cui LN, Saeb-Parsy K, Dyball RE . Neurones in the supraoptic nucleus of the rat are regulated by a projection from the suprachiasmatic nucleus. J Physiol 1997; 502 (Part 1): 149–159. ArticleCAS Google Scholar