Multiple regulatory sites in large-conductance calcium-activated potassium channels (original) (raw)

References

  1. Barrett, J. N., Magleby, K. L. & Pallotta, B. S. Properties of single calcium-activated potassium channels in cultured rat muscle. J. Physiol. (Lond.) 331, 211–230 (1982)
    Article CAS Google Scholar
  2. Moczydlowski, E. & Latorre, R. Gating kinetics of Ca2+-activated K+ channels from rat muscle incorporated into planar lipid bilayers. Evidence for two voltage-dependent Ca2+ binding reactions. J. Gen. Physiol. 82, 511–542 (1983)
    Article CAS Google Scholar
  3. Cox, D. H., Cui, J. & Aldrich, R. W. Allosteric gating of a large conductance Ca-activated K+ channel. J. Gen. Physiol. 110, 257–281 (1997)
    Article CAS Google Scholar
  4. Cox, D. & Aldrich, R. Role of the β1 subunit in large-conductance Ca2+-activated K+ channel gating energetics. Mechanisms of enhanced Ca2+ sensitivity. J. Gen. Physiol. 116, 411–432 (2000)
    Article CAS Google Scholar
  5. Zhang, X., Solaro, C. & Lingle, C. Allosteric regulation of BK channel gating by Ca2+ and Mg2+ through a non-selective, low affinity divalent cation site. J. Gen. Physiol. 118, 607–635 (2001)
    Article CAS Google Scholar
  6. Cui, J., Cox, D. H. & Aldrich, R. W. Intrinsic voltage dependence and Ca2+ regulation of mslo large conductance Ca-activated K+ channels. J. Gen. Physiol. 109, 647–673 (1997)
    Article CAS Google Scholar
  7. Cui, J. & Aldrich, R. W. Allosteric linkage between voltage and Ca2+-dependent activation of BK-type mslo1 K+ channels. Biochemistry 39, 15612–15619 (2000)
    Article CAS Google Scholar
  8. Horrigan, F. T., Cui, J. & Aldrich, R. W. Allosteric voltage gating of potassium channels I. Mslo ionic currents in the absence of Ca2+. J. Gen. Physiol. 114, 277–304 (2002)
    Article Google Scholar
  9. Schreiber, M. & Salkoff, L. A novel calcium-sensing domain in the BK channel. Biophys. J. 73, 1355–1363 (1997)
    Article CAS Google Scholar
  10. Schreiber, M., Yuan, A. & Salkoff, L. Transplantable sites confer calcium sensitivity to BK channels. Nature Neurosci. 2, 416–421 (1999)
    Article CAS Google Scholar
  11. Bian, S., Favre, I. & Moczydlowski, E. Ca2+-binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca2+-dependent activation. Proc. Natl Acad. Sci. USA 98, 4776–4781 (2001)
    Article ADS CAS Google Scholar
  12. Jiang, Y., Pico, A., Cadene, M., Chait, B. T. & MacKinnon, R. Structure of the RCK domain from the E. coli K+ channel and demonstration of its presence in the human BK channel. Neuron 29, 593–601 (2001)
    Article CAS Google Scholar
  13. Shi, J. & Cui, J. Intracellular Mg2+ enhances the function of BK-type Ca2+-activated K+ channels. J. Gen. Physiol. 118, 589–606 (2001)
    Article ADS CAS Google Scholar
  14. Shao, L. R., Halvorsrud, R., Borg-Graham, L. & Storm, J. F. The role of BK-type Ca2+-dependent K+ channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells. J. Physiol. 521(1), 135–146 (1999)
    Article CAS Google Scholar
  15. Jones, E. M., Gray-Keller, M. & Fettiplace, R. The role of Ca2+-activated K+ channel spliced variants in the tonotopic organization of the turtle cochlea. J. Physiol. 518, 653–665 (1999)
    Article CAS Google Scholar
  16. Adelman, J. P. et al. Calcium-activated potassium channels expressed from cloned complementary DNAs. Neuron 9, 209–216 (1992)
    Article CAS Google Scholar
  17. Butler, A., Tsunoda, S., McCobb, D. P., Wei, A. & Salkoff, L. mSlo, a complex mouse gene encoding “maxi” calcium-activated potassium channels. Science 261, 221–224 (1993)
    Article ADS CAS Google Scholar
  18. Shen, K. Z. et al. Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: evidence for tetrameric channel formation. Pflugers Arch. 426, 440–445 (1994)
    Article CAS Google Scholar
  19. Meera, P., Wallner, M., Song, M. & Toro, L. Large conductance voltage- and calcium-dependent K+ channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus. Proc. Natl Acad. Sci. USA 94, 14066–14071 (1997)
    Article ADS CAS Google Scholar
  20. Wei, A., Solaro, C., Lingle, C. & Salkoff, L. Calcium sensitivity of BK-type KCa channels determined by a separable domain. Neuron 13, 671–681 (1994)
    Article CAS Google Scholar
  21. Jiang, Y. et al. Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417, 515–522 (2002)
    Article ADS CAS Google Scholar
  22. Bellamacina, C. R. The nicotinamide dinucleotide binding motif: a comparison of nucleotide binding proteins. FASEB J. 10, 1257–1269 (1996)
    Article CAS Google Scholar
  23. Schreiber, M. et al. Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes. J. Biol. Chem. 273, 3509–3516 (1998)
    Article CAS Google Scholar
  24. Moss, B. L. & Magleby, K. L. Gating and conductance properties of BK channels are modulated by the S9-S10 tail domain of the alpha subunit. A study of mSlo1 and mSlo3 wild-type and chimeric channels. J. Gen. Physiol. 118, 711–734 (2001)
    Article CAS Google Scholar
  25. Golowasch, J., Kirkwood, A. & Miller, C. Allosteric effects of Mg2+ on the gating of Ca2+-activated K+ channels from mammalian skeletal muscle. J. Exp. Biol. 124, 5–13 (1986)
    CAS PubMed Google Scholar
  26. Oberhauser, A., Alvarez, O. & Latorre, R. Activation by divalent cations of a Ca2+-activated K+ channel from skeletal muscle membrane. J. Gen. Physiol. 92, 67–86 (1988)
    Article CAS Google Scholar
  27. Ferguson, W. B. Competitive Mg2+ block of a large-conductance, Ca2+-activated K+ channel in rat skeletal muscle. Ca2+, Sr2+, and Ni2+ also block. J. Gen. Physiol. 98, 163–181 (1991)
    Article CAS Google Scholar
  28. Rothberg, B. S. & Magleby, K. L. Gating kinetics of single large-conductance Ca2+-activated K+ channels in high Ca2+ suggest a two-tiered allosteric gating mechanism. J. Gen. Physiol. 114, 93–124 (1999)
    Article CAS Google Scholar
  29. Xia, X. M., Ding, J. P. & Lingle, C. J. Molecular basis for the inactivation of Ca2+- and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumour cells. J. Neurosci. 19, 5255–5264 (1999)
    Article CAS Google Scholar
  30. Lingle, C., Zeng, X.-H., Ding, J.-P. & Xia, X.-M. Inactivation of BK channels mediated by the N-terminus of the β3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockade. J. Gen. Physiol. 117, 583–605 (2001)
    Article CAS Google Scholar

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