The harlequin mouse mutation downregulates apoptosis-inducing factor (original) (raw)

• Cassarino, D. S. & Bennett, J. P. Jr An evaluation of the role of mitochondria in neurodegenerative diseases: mitochondrial mutations and oxidative pathology, protective nuclear responses, and cell death in neurodegeneration. Brain Res. Brain Res. Rev. 29, 1–25 (1999)
  Article CAS Google Scholar
• Sayre, L. M., Smith, M. A. & Perry, G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr. Med. Chem. 8, 721–738 (2001)
  Article CAS Google Scholar
• Busser, J., Geldmacher, D. S. & Herrup, K. Ectopic cell cycle proteins predict the sites of neuronal cell death in Alzheimer's disease brain. J. Neurosci. 18, 2801–2807 (1998)
  Article CAS Google Scholar
• McShea, A., Wahl, A. F. & Smith, M. A. Re-entry into the cell cycle: a mechanism for neurodegeneration in Alzheimer disease. Med. Hypotheses 52, 525–527 (1999)
  Article CAS Google Scholar
• Yang, Y., Geldmacher, D. S. & Herrup, K. DNA replication precedes neuronal cell death in Alzheimer's disease. J. Neurosci. 21, 2661–2668 (2001)
  Article CAS Google Scholar
• Nagy, Z., Esiri, M. M. & Smith, A. D. Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions. Acta Neuropathol. (Berl.) 93, 294–300 (1997)
  Article CAS Google Scholar
• Osuga, H. et al. Cyclin-dependent kinases as a therapeutic target for stroke. Proc. Natl Acad. Sci. USA 97, 10254–10259 (2000)
  Article ADS CAS Google Scholar
• Katchanov, J. et al. Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death. J. Neurosci. 21, 5045–5053 (2001)
  Article CAS Google Scholar
• Herrup, K. & Busser, J. C. The induction of multiple cell cycle events precedes target-related neuronal death. Development 121, 2385–2395 (1995)
  CAS PubMed Google Scholar
• Migheli, A. et al. A cell cycle alteration precedes apoptosis of granule cell precursors in the weaver mouse cerebellum. Am. J. Pathol. 155, 365–373 (1999)
  Article CAS Google Scholar
• Gill, J. S. & Windebank, A. J. Cisplatin-induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle. J. Clin. Invest. 101, 2842–2850 (1998)
  Article CAS Google Scholar
• ElShamy, W. M., Fridvall, L. K. & Ernfors, P. Growth arrest failure, G1 restriction point override, and S phase death of sensory precursor cells in the absence of neurotrophin-3. Neuron 21, 1003–1015 (1998)
  Article CAS Google Scholar
• Feddersen, R. M., Ehlenfeldt, R., Yunis, W. S., Clark, H. B. & Orr, H. T. Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice. Neuron 9, 955–966 (1992)
  Article CAS Google Scholar
• Hammang, J. P. et al. Oncogene expression in retinal horizontal cells of transgenic mice results in a cascade of neurodegeneration. Neuron 10, 1197–1209 (1993)
  Article CAS Google Scholar
• Barber, B. R. Research news. Mouse News Lett. 45, 34–35 (1971)
  Google Scholar
• Bronson, R. T., Lane, P. W., Harris, B. S. & Davisson, M. T. Harlequin (Hq) produces progressive cerebellar atrophy. Mouse Genome 87, 110 (1990)
  Google Scholar
• Williams, J. Chemistry and Biochemistry of Flavoenzymes (ed. Muller, F.)) 121–211 (CRC Press, Boca Raton, 1995)
  Google Scholar
• Susin, S. A. et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397, 441–446 (1999)
  Article ADS CAS Google Scholar
• Mustacich, D. & Powis, G. Thioredoxin reductase. Biochem. J. 346, 1–8 (2000)
  Article CAS Google Scholar
• Miramar, M. D. et al. NADH oxidase activity of mitochondrial apoptosis-inducing factor. J. Biol. Chem. 276, 16391–16398 (2001)
  Article CAS Google Scholar
• Joza, N. et al. Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death. Nature 410, 549–554 (2001)
  Article ADS CAS Google Scholar
• Heintz, N. & Zoghbi, H. Y. Insights from mouse models into the molecular basis of neurodegeneration. Annu. Rev. Physiol. 62, 779–802 (2000)
  Article CAS Google Scholar
• Hawes, N. L. et al. Retinal degeneration 6 (rd6): a new mouse model for human retinitis punctata albescens. Invest. Ophthalmol. Vis. Sci. 41, 3149–3157 (2000)
  CAS PubMed Google Scholar
• Coffin, J. M., Stoye, J. P. & Frankel, W. N. Genetics of endogenous murine leukemia viruses. Ann. NY Acad. Sci. 567, 39–49 (1989)
  Article ADS CAS Google Scholar
• Taylor, B. A. & Rowe, L. A mouse linkage testing stock possessing multiple copies of the endogenous ecotropic murine leukemia virus genome. Genomics 5, 221–232 (1989)
  Article CAS Google Scholar
• Coffin, J. RNA Tumor Viruses: Molecular Biology of Tumor Viruses (eds Weiss, R.Teich, N.Varmus, H. & Coffin, J.) 261–369 (Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, 1984)
  Google Scholar
• Droge, W. Free radicals in the physiological control of cell function. Physiol. Rev. 82, 47–95 (2002)
  Article CAS Google Scholar
• Deisseroth, A. & Dounce, A. L. Catalase: physical and chemical properties, mechanism of catalysis, and physiological role. Physiol. Rev. 50, 319–375 (1970)
  Article CAS Google Scholar
• Baillie, T. & Slatter, J. Glutathione: a vehicle for the transport of chemically reactive metabolites in vivo. Acc. Chem. Res. 24, 264–270 (1991)
  Article CAS Google Scholar
• Mate, M. J. et al. The crystal structure of the mouse apoptosis-inducing factor AIF. Nature Struct. Biol. 9, 442–446 (2002)
  Article CAS Google Scholar
• White, A. R. et al. Survival of cultured neurons from amyloid precursor protein knock-out mice against Alzheimer's amyloid-beta toxicity and oxidative stress. J. Neurosci. 18, 6207–6217 (1998)
  Article CAS Google Scholar
• Costa, G. L. et al. Targeting rare populations of murine antigen-specific T lymphocytes by retroviral transduction for potential application in gene therapy for autoimmune disease. J. Immunol. 164, 3581–3590 (2000)
  Article CAS Google Scholar
• Shackelford, R. E., Kaufmann, W. K. & Paules, R. S. Oxidative stress and cell cycle checkpoint function. Free Radical Biol. Med. 28, 1387–1404 (2000)
  Article CAS Google Scholar
• Kurki, P., Vanderlaan, M., Dolbeare, F., Gray, J. & Tan, E. M. Expression of proliferating cell nuclear antigen (PCNA)/cyclin during the cell cycle. Exp. Cell Res. 166, 209–219 (1986)
  Article CAS Google Scholar
• Kimura, H., Ohtomo, T., Yamaguchi, M., Ishii, A. & Sugimoto, K. Mouse MCM proteins: complex formation and transportation to the nucleus. Genes Cells 1, 977–993 (1996)
  Article CAS Google Scholar
• Frade, J. M. Unscheduled re-entry into the cell cycle induced by NGF precedes cell death in nascent retinal neurones. J. Cell Sci. 113, 1139–1148 (2000)
  CAS PubMed Google Scholar
• Raina, A. K., Zhu, X., Monteiro, M., Takeda, A. & Smith, M. A. Abortive oncogeny and cell cycle-mediated events in Alzheimer disease. Prog. Cell Cycle Res. 4, 235–242 (2000)
  Article CAS Google Scholar
• Daugas, E. et al. Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis. FEBS Lett. 476, 118–123 (2000)
  Article CAS Google Scholar
• Mundy, W. R. & Freudenrich, T. M. Sensitivity of immature neurons in culture to metal-induced changes in reactive oxygen species and intracellular free calcium. Neurotoxicology 21, 1135–1144 (2000)
  CAS PubMed Google Scholar
• Griendling, K. K., Sorescu, D., Lassegue, B. & Ushio-Fukai, M. Modulation of protein kinase activity and gene expression by reactive oxygen species and their role in vascular physiology and pathophysiology. Arterioscler. Thromb. Vasc. Biol. 20, 2175–2183 (2000)
  Article CAS Google Scholar
• Lavoie, J. N., Rivard, N., L'Allemain, G. & Pouyssegur, J. A temporal and biochemical link between growth factor-activated MAP kinases, cyclin D1 induction and cell cycle entry. Prog. Cell Cycle Res. 2, 49–58 (1996)
  Article CAS Google Scholar
• Lee, E. Y. et al. Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 8, 2008–2021 (1994)
  Article CAS Google Scholar
• Ackerman, S. L. et al. The mouse rostral cerebellar malformation gene encodes an UNC-5-like protein. Nature 386, 838–842 (1997)
  Article ADS CAS Google Scholar
• Lynn, R. B., Bechtold, L. S. & Miselis, R. R. Ultrastructure of bombesin-like immunoreactive nerve terminals in the nucleus of the solitary tract and the dorsal motor nucleus. J. Auton. Nerv. Syst. 62, 174–182 (1997)
  Article CAS Google Scholar
• Sheldon, M. et al. Scrambler and yotari disrupt the disabled gene and produce a reeler- like phenotype in mice. Nature 389, 730–733 (1997)
  Article ADS CAS Google Scholar
• Cambray-Deakin, M. A. Neural Cell Culture: A Practical Approach (ed. Wilkin, J. C. a. G.) 3–13 (IRL Press, Oxford, 1995)
  Google Scholar
• Grignani, F. et al. High-efficiency gene transfer and selection of human hematopoietic progenitor cells with a hybrid EBV/retroviral vector expressing the green fluorescence protein. Cancer Res. 58, 14–19 (1998)
  CAS PubMed Google Scholar