Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair (original) (raw)

References

  1. Vettese-Dadey, M. et al. Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. EMBO J. 15, 2508–2518 (1996)
    Article CAS Google Scholar
  2. Lee, D. Y., Hayes, J. J., Pruss, D. & Wolffe, A. P. A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 72, 73–84 (1993)
    Article CAS Google Scholar
  3. Brownell, J. E. et al. Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation. Cell 84, 843–851 (1996)
    Article CAS Google Scholar
  4. Braunstein, M., Sobel, R. E., Allis, C. D., Turner, B. M. & Broach, J. R. Efficient transcriptional silencing in Saccharomyces cerevisiae requires a heterochromatin histone acetylation pattern. Mol. Cell. Biol. 16, 4349–4356 (1996)
    Article CAS Google Scholar
  5. Allfrey, V. G., Pogo, B. G., Littau, V. C., Gershey, E. L. & Mirsky, A. E. Histone acetylation in insect chromosomes. Science 159, 314–316 (1968)
    Article ADS CAS Google Scholar
  6. Strahl, B. D. & Allis, C. D. The language of covalent histone modifications. Nature 403, 41–45 (2000)
    ADS CAS Google Scholar
  7. Barlev, N. A. et al. Repression of GCN5 histone acetyltransferase activity via bromodomain-mediated binding and phosphorylation by the Ku-DNA-dependent protein kinase complex. Mol. Cell. Biol. 18, 1349–1358 (1998)
    Article CAS Google Scholar
  8. Iizuka, M. & Stillman, B. Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. J. Biol. Chem. 274, 23027–23034 (1999)
    Article CAS Google Scholar
  9. Burke, T. W., Cook, J. G., Asano, M. & Nevins, J. R. Replication factors MCM2 and ORC1 interact with the histone acetyltransferase HBO1. J. Biol. Chem. 276, 15397–15408 (2001)
    Article CAS Google Scholar
  10. Megee, P. C., Morgan, B. A., Mittman, B. A. & Smith, M. M. Genetic analysis of histone H4: essential role of lysines subject to reversible acetylation. Science 247, 841–845 (1990)
    Article ADS CAS Google Scholar
  11. Megee, P. C., Morgan, B. A. & Smith, M. M. Histone H4 and the maintenance of genome integrity. Genes Dev. 9, 1716–1727 (1995)
    Article CAS Google Scholar
  12. Clarke, A. S., Lowell, J. E., Jacobson, S. J. & Pillus, L. Esa1p is an essential histone acetyltransferase required for cell cycle progression. Mol. Cell. Biol. 19, 2515–2526 (1999)
    Article CAS Google Scholar
  13. Reid, J. L., Iyer, V. R., Brown, P. O. & Struhl, K. Coordinate regulation of yeast ribosomal protein genes is associated with targeted recruitment of Esa1 histone acetylase. Mol. Cell 6, 1297–1307 (2000)
    Article CAS Google Scholar
  14. Ikura, T. et al. Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell 102, 463–473 (2000)
    Article CAS Google Scholar
  15. Boulton, S. J. & Jackson, S. P. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways. EMBO J. 15, 5093–5103 (1996)
    Article CAS Google Scholar
  16. Tsukamoto, Y., Kato, J. & Ikeda, H. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature 388, 900–903 (1997)
    Article ADS CAS Google Scholar
  17. Wilson, T. E. & Lieber, M. R. Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase β (Pol4)-dependent pathway. J. Biol. Chem. 274, 23599–23609 (1999)
    Article CAS Google Scholar
  18. D'Arpa, P., Beardmore, C. & Liu, L. F. Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons. Cancer Res. 50, 6919–6924 (1990)
    CAS PubMed Google Scholar
  19. Harata, M. et al. The nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4, interacts with core histones. Mol. Biol. Cell 10, 2595–2605 (1999)
    Article CAS Google Scholar
  20. Galarneau, L. et al. Multiple links between the NuA4 histone acetyltransferase complex and epigenetic control of transcription. Mol. Cell 5, 927–937 (2000)
    Article CAS Google Scholar
  21. Martin, S. G., Laroche, T., Suka, N., Grunstein, M. & Gasser, S. M. Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97, 621–633 (1999)
    Article CAS Google Scholar
  22. Vignali, M., Steger, D. J., Neely, K. E. & Workman, J. L. Distribution of acetylated histones resulting from Gal4–VP16 recruitment of SAGA and NuA4 complexes. EMBO J. 19, 2629–2640 (2000)
    Article CAS Google Scholar
  23. Kowalczykowski, S. C. Initiation of genetic recombination and recombination-dependent replication. Trends Biochem. Sci. 25, 156–165 (2000)
    Article CAS Google Scholar
  24. Downs, J. A., Lowndes, N. F. & Jackson, S. P. A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature 408, 1001–1004 (2000)
    Article ADS CAS Google Scholar
  25. Grant, P. A. et al. Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev. 11, 1640–1650 (1997)
    Article CAS Google Scholar
  26. Lin, Y. S., Carey, M. F., Ptashne, M. & Green, M. R. GAL4 derivatives function alone and synergistically with mammalian activators in vitro. Cell 54, 659–664 (1988)
    Article CAS Google Scholar
  27. Owen-Hughes, T. et al. Analysis of nucleosome disruption by ATP-driven chromatin remodeling complexes. Methods Mol. Biol. 119, 319–331 (1999)
    CAS PubMed Google Scholar

Download references