Sortilin is essential for proNGF-induced neuronal cell death (original) (raw)
References
Petersen, C. M. et al. Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography. J. Biol. Chem.272, 3599–3605 (1997) CASPubMed Google Scholar
Hermey, G. et al. Characterization of sorCS1, an alternatively spliced receptor with completely different cytoplasmic domains that mediate different trafficking in cells. J. Biol. Chem.278, 7390–7396 (2003) CASPubMed Google Scholar
Jacobsen, L. et al. Activation and functional characterization of the mosaic receptor SorLA/LR11. J. Biol. Chem.276, 22788–22796 (2001) CASPubMed Google Scholar
Mazella, J. et al. The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor. J. Biol. Chem.273, 26273–26276 (1998) CASPubMed Google Scholar
Munck, P. C. et al. Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding. EMBO J.18, 595–604 (1999) Google Scholar
Sarret, P. et al. Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system. J. Comp. Neurol.461, 483–505 (2003) CASPubMed Google Scholar
Hermans-Borgmeyer, I., Hermey, G., Nykjaer, A. & Schaller, C. Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development. Brain Res. Mol. Brain Res.65, 216–219 (1999) CASPubMed Google Scholar
Beattie, M. S. et al. ProNGF induces p75-mediated death of oligodendrocytes following spinal cord injury. Neuron36, 375–386 (2002) CASPubMedPubMed Central Google Scholar
Hasan, W., Pedchenko, T., Krizsan-Agbas, D., Baum, L. & Smith, P. G. Sympathetic neurons synthesize and secrete pro-nerve growth factor protein. J. Neurobiol.57, 38–53 (2003) CASPubMed Google Scholar
Chao, M. V. Neurotrophins and their receptors: a convergence point for many signalling pathways. Nature Rev. Neurosci.4, 299–309 (2003) CAS Google Scholar
Lee, R., Kermani, P., Teng, K. K. & Hempstead, B. L. Regulation of cell survival by secreted proneurotrophins. Science294, 1945–1948 (2001) ADSCAS Google Scholar
Esposito, D. et al. The cytoplasmic and transmembrane domains of the p75 and Trk A receptors regulate high affinity binding to nerve growth factor. J. Biol. Chem.276, 32687–32695 (2001) CASPubMed Google Scholar
Mahadeo, D., Kaplan, L., Chao, M. V. & Hempstead, B. L. High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors. J. Biol. Chem.269, 6884–6891 (1994) CASPubMed Google Scholar
Fahnestock, M., Michalski, B., Xu, B. & Coughlin, M. D. The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Mol. Cell. Neurosci.18, 210–220 (2001) CASPubMed Google Scholar
Heymach, J. V. Jr & Shooter, E. M. The biosynthesis of neurotrophin heterodimers by transfected mammalian cells. J. Biol. Chem.270, 12297–12304 (1995) CASPubMed Google Scholar
Nielsen, M. S. et al. The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein. EMBO J.20, 2180–2190 (2001) CASPubMedPubMed Central Google Scholar
Gargano, N., Levi, A. & Alema, S. Modulation of nerve growth factor internalization by direct interaction between p75 and TrkA receptors. J. Neurosci. Res.50, 1–12 (1997) CASPubMed Google Scholar
Bronfman, F. C., Tcherpakov, M., Jovin, T. M. & Fainzilber, M. Ligand-induced internalization of the p75 neurotrophin receptor: a slow route to the signaling endosome. J. Neurosci.23, 3209–3220 (2003) CASPubMed Google Scholar
Shonukan, O., Bagayogo, I., McCrea, P., Chao, M. & Hempstead, B. Neurotrophin-induced melanoma cell migration is mediated through the actin-bundling protein fascin. Oncogene22, 3616–3623 (2003) CASPubMed Google Scholar
Lee, K. F. et al. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell69, 737–749 (1992) CASPubMed Google Scholar
Rattenholl, A. et al. The pro-sequence facilitates folding of human nerve growth factor from Escherichia coli inclusion bodies. Eur. J. Biochem.268, 3296–3303 (2001) CAS Google Scholar
Hempstead, B. L., Schleifer, L. S. & Chao, M. V. Expression of functional nerve growth factor receptors after gene transfer. Science243, 373–375 (1989) ADSCASPubMed Google Scholar
Hempstead, B. L., Martin-Zanca, D., Kaplan, D. R., Parada, L. F. & Chao, M. V. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature350, 678–683 (1991) ADSCASPubMed Google Scholar
Nykjaer, A. et al. Cubilin dysfunction causes abnormal metabolism of the steroid hormone 25(OH) vitamin D(3). Proc. Natl Acad. Sci. USA98, 13895–13900 (2001) ADSCASPubMed Google Scholar
Einheber, S., Milner, T. A., Giancotti, F. & Salzer, J. L. Axonal regulation of Schwann cell integrin expression suggests a role for α6 β4 in myelination. J. Cell Biol.123, 1223–1236 (1993) CASPubMed Google Scholar
Nykjaer, A. et al. Mannose 6-phosphate/insulin-like growth factor-II receptor targets the urokinase receptor to lysosomes via a novel binding interaction. J. Cell Biol.141, 815–828 (1998) CASPubMedPubMed Central Google Scholar
Wang, S. et al. p75(NTR) mediates neurotrophin-induced apoptosis of vascular smooth muscle cells. Am. J. Pathol.157, 1247–1258 (2000) CASPubMedPubMed Central Google Scholar
Mitsui, C., Sakai, K., Ninomiya, T. & Koike, T. Involvement of TLCK-sensitive serine protease in colchicine-induced cell death of sympathetic neurons in culture. J. Neurosci. Res.66, 601–611 (2001) CASPubMed Google Scholar
Bamji, S. X. et al. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol.140, 911–923 (1998) CASPubMedPubMed Central Google Scholar