APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses (original) (raw)

References

1. Boeke, J. D. & Stoye, J. in Retroviruses (eds Coffin, J. M., Hugues, S. H. & Varmus, H. E.) 343–436 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, 1997)
   Google Scholar
2. Bannert, N. & Kurth, R. Retroelements and the human genome: New perspectives on an old relation. Proc. Natl Acad. Sci. USA 101(suppl. 2), 14572–14579 (2004)
   Article ADS CAS PubMed PubMed Central Google Scholar
3. Johnson, W. E. & Coffin, J. M. Constructing primate phylogenies from ancient retrovirus sequences. Proc. Natl Acad. Sci. USA 96, 10254–10260 (1999)
   Article ADS CAS PubMed PubMed Central Google Scholar
4. Kazazian, H. H. Jr. Mobile elements: drivers of genome evolution. Science 303, 1626–1632 (2004)
   Article ADS CAS PubMed Google Scholar
5. Lower, R. The pathogenic potential of endogenous retroviruses: facts and fantasies. Trends Microbiol. 7, 350–356 (1999)
   Article CAS PubMed Google Scholar
6. Dewannieux, M., Dupressoir, A., Harper, F., Pierron, G. & Heidmann, T. Identification of autonomous IAP LTR retrotransposons mobile in mammalian cells. Nature Genet. 36, 534–539 (2004)
   Article CAS PubMed Google Scholar
7. Ribet, D., Dewannieux, M. & Heidmann, T. An active murine transposon family pair: retrotransposition of ‘master’ MusD copies and ETn trans-mobilization. Genome Res. 14, 2261–2267 (2004)
   Article CAS PubMed PubMed Central Google Scholar
8. Bourc'his, D. & Bestor, T. H. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L. Nature 431, 96–99 (2004)
   Article ADS CAS PubMed Google Scholar
9. Sheehy, A. M., Gaddis, N. C., Choi, J. D. & Malim, M. H. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 418, 646–650 (2002)
   ADS CAS PubMed Google Scholar
10. Mangeat, B. et al. Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts. Nature 424, 99–103 (2003)
    Article ADS CAS PubMed Google Scholar
11. Harris, R. S. et al. DNA deamination mediates innate immunity to retroviral infection. Cell 113, 803–809 (2003)
    Article CAS PubMed Google Scholar
12. Mariani, R. et al. Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Cell 114, 21–31 (2003)
    Article CAS PubMed Google Scholar
13. Heidmann, O. & Heidmann, T. Retrotransposition of a mouse IAP sequence tagged with an indicator gene. Cell 64, 159–170 (1991)
    Article CAS PubMed Google Scholar
14. Dupressoir, A. & Heidmann, T. Germ line-specific expression of intracisternal A-particle retrotransposons in transgenic mice. Mol. Cell. Biol. 16, 4495–4503 (1996)
    Article CAS PubMed PubMed Central Google Scholar
15. Baust, C. et al. Structure and expression of mobile ETnII retroelements and their coding-competent MusD relatives in the mouse. J. Virol. 77, 11448–11458 (2003)
    Article CAS PubMed PubMed Central Google Scholar
16. Jarmuz, A. et al. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics 79, 285–296 (2002)
    Article CAS PubMed Google Scholar
17. Wedekind, J. E., Dance, G. S., Sowden, M. P. & Smith, H. C. Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. Trends Genet. 19, 207–216 (2003)
    Article CAS PubMed Google Scholar
18. Lecossier, D., Bouchonnet, F., Clavel, F. & Hance, A. J. Hypermutation of HIV-1 DNA in the absence of the Vif protein. Science 300, 1112 (2003)
    Article CAS PubMed Google Scholar
19. Suspene, R. et al. APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase. Nucleic Acids Res. 32, 2421–2429 (2004)
    Article CAS PubMed PubMed Central Google Scholar
20. Yu, Q. et al. Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome. Nature Struct. Mol. Biol. 11, 435–442 (2004)
    Article CAS Google Scholar
21. Wiegand, H. L., Doehle, B. P., Bogerd, H. P. & Cullen, B. R. A second human antiretroviral factor, APOBEC3F, is suppressed by the HIV-1 and HIV-2 Vif proteins. EMBO J. 23, 2451–2458 (2004)
    Article CAS PubMed PubMed Central Google Scholar
22. Bishop, K. N., Holmes, R. K., Sheehy, A. M. & Malim, M. H. APOBEC-mediated editing of viral RNA. Science 305, 645 (2004)
    Article CAS PubMed Google Scholar
23. Marin, M., Rose, K. M., Kozak, S. L. & Kabat, D. HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. Nature Med. 9, 1398–1403 (2003)
    Article CAS PubMed Google Scholar
24. Stopak, K., de Noronha, C., Yonemoto, W. & Greene, W. C. HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol. Cell 12, 591–601 (2003)
    Article CAS PubMed Google Scholar
25. Sawyer, S. L., Emerman, M. & Malik, H. S. Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. PLoS Biol. 2, E275 (2004)
    Article PubMed PubMed Central Google Scholar
26. Moran, J. V. et al. High frequency retrotransposition in cultured mammalian cells. Cell 87, 917–927 (1996)
    Article CAS PubMed Google Scholar
27. Goodier, J. L., Ostertag, E. M., Du, K. & Kazazian, H. H. Jr. A novel active L1 retrotransposon subfamily in the mouse. Genome Res. 11, 1677–1685 (2001)
    Article CAS PubMed PubMed Central Google Scholar
28. Liddament, M. T., Brown, W. L., Schumacher, A. J. & Harris, R. S. APOBEC3F properties and hypermutation preferences indicate activity against HIV-1 in vivo. Curr. Biol. 14, 1385–1391 (2004)
    Article CAS PubMed Google Scholar
29. Turelli, P., Vianin, S. & Trono, D. The innate antiretroviral factor APOBEC3G does not affect human LINE-1 retrotransposition in a cell culture assay. J. Biol. Chem. 279, 43371–43373 (2004)
    Article CAS PubMed Google Scholar
30. Esnault, C., Casella, J. F. & Heidmann, T. A Tetrahymena thermophila ribozyme-based indicator gene to detect transposition of marked retroelements in mammalian cells. Nucleic Acids Res. 30, e49 (2002)
    Article PubMed PubMed Central Google Scholar

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