Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin (original) (raw)

References

  1. Jenuwein, T. & Allis, C. D. Translating the histone code. Science 293, 1074–1080 (2001)
    Article CAS Google Scholar
  2. Bannister, A. J. et al. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410, 120–124 (2001)
    Article ADS CAS Google Scholar
  3. Jacobs, S. A. et al. Specificity of the HP1 chromo domain for the methylated N-terminus of histone H3. EMBO J. 20, 5232–5241 (2001)
    Article CAS Google Scholar
  4. Lachner, M., O'Carroll, D., Rea, S., Mechtler, K. & Jenuwein, T. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410, 116–120 (2001)
    Article ADS CAS Google Scholar
  5. Nielsen, P. R. et al. Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9. Nature 416, 103–107 (2002)
    Article ADS CAS Google Scholar
  6. Jacobs, S. A. & Khorasanizadeh, S. Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail. Science 295, 2080–2083 (2002)
    Article ADS CAS Google Scholar
  7. Hsu, J. Y. et al. Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102, 279–291 (2000)
    Article CAS Google Scholar
  8. Fischle, W., Wang, Y. & Allis, C. D. Binary switches and modification cassettes in histone biology and beyond. Nature 425, 475–479 (2003)
    Article ADS CAS Google Scholar
  9. Gitlits, V. M., Macaulay, S. L., Toh, B. H. & Sentry, J. W. Novel human autoantibodies to phosphoepitopes on mitotic chromosomal autoantigens (MCAs). J. Investig. Med. 48, 172–182 (2000)
    CAS PubMed Google Scholar
  10. Murzina, N., Verreault, A., Laue, E. & Stillman, B. Heterochromatin dynamics in mouse cells: interaction between chromatin assembly factor 1 and HP1 proteins. Mol. Cell 4, 529–540 (1999)
    Article CAS Google Scholar
  11. Sugimoto, K., Tasaka, H. & Dotsu, M. Molecular behaviour in living mitotic cells of human centromere heterochromatin protein HPLα ectopically expressed as a fusion to red fluorescent protein. Cell Struct. Funct. 26, 705–718 (2001)
    Article CAS Google Scholar
  12. Schmiedeberg, L., Weisshart, K., Diekmann, S., Meyer Zu Hoerste, G. & Hemmerich, P. High- and low-mobility populations of HP1 in heterochromatin of mammalian cells. Mol. Biol. Cell 15, 2819–2833 (2004)
    Article CAS Google Scholar
  13. Sullivan, B. A., Blower, M. D. & Karpen, G. H. Determining centromere identity: cyclical stories and forking paths. Nature Rev. Genet. 2, 584–596 (2001)
    Article CAS Google Scholar
  14. Mellone, B. G. & Allshire, R. C. Stretching it: putting the CEN(P-A) in centromere. Curr. Opin. Genet. Dev. 13, 191–198 (2003)
    Article CAS Google Scholar
  15. Amor, D. J., Kalitsis, P., Sumer, H. & Choo, K. H. Building the centromere: from foundation proteins to 3D organization. Trends Cell Biol. 14, 359–368 (2004)
    Article CAS Google Scholar
  16. Fischle, W. et al. Molecular basis for the discrimination of repressive methyl-lysine marks in histone H3 by Polycomb and HP1 chromodomains. Genes Dev. 17, 1870–1881 (2003)
    Article CAS Google Scholar
  17. Bernard, P. et al. Requirement of heterochromatin for cohesion at centromeres. Science 294, 2539–2542 (2001)
    Article ADS CAS Google Scholar
  18. Nonaka, N. et al. Recruitment of cohesin to heterochromatic regions by Swi6/HP1 in fission yeast. Nature Cell Biol. 4, 89–93 (2002)
    Article CAS Google Scholar
  19. Grewal, S. I. & Rice, J. C. Regulation of heterochromatin by histone methylation and small RNAs. Curr. Opin. Cell Biol. 16, 230–238 (2004)
    Article CAS Google Scholar
  20. Earnshaw, W., Bordwell, B., Marino, C. & Rothfield, N. Three human chromosomal autoantigens are recognized by sera from patients with anti-centromere antibodies. J. Clin. Invest. 77, 426–430 (1986)
    Article CAS Google Scholar
  21. Hauf, S. et al. The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint. J. Cell Biol. 161, 281–294 (2003)
    Article CAS Google Scholar
  22. Rea, S. et al. Regulation of chromatin structure by site-specific histone H3 methyltransferases. Nature 406, 593–599 (2000)
    Article ADS CAS Google Scholar
  23. Giet, R. & Glover, D. M. Drosophila aurora B kinase is required for histone H3 phosphorylation and condensin recruitment during chromosome condensation and to organize the central spindle during cytokinesis. J. Cell Biol. 152, 669–682 (2001)
    Article CAS Google Scholar
  24. Mellone, B. G. et al. Centromere silencing and function in fission yeast is governed by the amino terminus of histone H3. Curr. Biol. 13, 1748–1757 (2003)
    Article CAS Google Scholar
  25. Wei, Y., Yu, L., Bowen, J., Gorovsky, M. A. & Allis, C. D. Phosphorylation of histone H3 is required for proper chromosome condensation and segregation. Cell 97, 99–109 (1999)
    Article CAS Google Scholar
  26. Mateescu, B., England, P., Halgand, F., Yaniv, M. & Muchardt, C. Tethering of HP1 proteins to chromatin is relieved by phosphoacetylation of histone H3. EMBO Rep. 5, 490–496 (2004)
    Article CAS Google Scholar
  27. Goto, H., Yasui, Y., Nigg, E. A. & Inagaki, M. Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes Cells 7, 11–17 (2002)
    Article CAS Google Scholar
  28. Gimenez-Abian, J. F. et al. Regulation of sister chromatid cohesion between chromosome arms. Curr. Biol. 14, 1187–1193 (2004)
    Article CAS Google Scholar
  29. Hirota, T., Gerlich, D., Koch, B., Ellenberg, J. & Peters, J. M. Distinct functions of condensin I and II in mitotic chromosome assembly. J. Cell Sci. 117, 6435–6445 (2004)
    Article CAS Google Scholar
  30. Sessa, F. et al. Mechanism of Aurora B activation by INCENP and inhibition by hesperadin. Mol. Cell 18, 379–391 (2005)
    Article CAS Google Scholar

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