Simultaneous measurement of multiple active kinase states using polychromatic flow cytometry (original) (raw)

References

  1. Fiering, S.N. et al. Improved FACS-Gal: flow cytometric analysis and sorting of viable eukaryotic cells expressing reporter gene constructs. Cytometry 12, 291–301 (1991).
    Article CAS Google Scholar
  2. Nolan, G.P., Fiering, S., Nicolas, J.F. & Herzenberg, L.A. Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-d-galactosidase activity after transduction of Escherichia coli lacZ. Proc. Natl. Acad. Sci. USA 85, 2603–2607 (1988).
    Article CAS Google Scholar
  3. Spinozzi, F. et al. The natural tyrosine kinase inhibitor genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells. Leuk. Res. 18, 431–439 (1994).
    Article CAS Google Scholar
  4. Hunter, T. Signaling—2000 and beyond. Cell 100, 113–127 (2000).
    Article CAS Google Scholar
  5. De Rosa, S.C., Herzenberg, L.A. & Roederer, M. 11-color, 13-parameter flow cytometry: identification of human naive T cells by phenotype, function, and T-cell receptor diversity. Nat. Med. 7, 245–248 (2001).
    Article CAS Google Scholar
  6. Franklin, R.A., Atherfold, P.A. & McCubrey, J.A. Calcium-induced ERK activation in human T lymphocytes occurs via p56(Lck) and CaM-kinase. Mol. Immunol. 37, 675–683 (2000).
    Article CAS Google Scholar
  7. Marhaba, R. et al. Tyrphostin A9 inhibits calcium release-dependent phosphorylations and calcium entry via calcium release-activated channel in Jurkat T cells. J. Immunol. 157, 1468–1473 (1996).
    CAS PubMed Google Scholar
  8. Montgomery, R.B., Moscatello, D.K., Wong, A.J., Cooper, J.A. & Stahl, W.L. Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor. J. Biol. Chem. 270, 30562–30566 (1995).
    Article CAS Google Scholar
  9. Morrison, P., Saltiel, A.R. & Rosner, M.R. Role of mitogen-activated protein kinase kinase in regulation of the epidermal growth factor receptor by protein kinase C. J. Biol. Chem. 271, 12891–12896 (1996).
    Article CAS Google Scholar
  10. Wang, X., McCullough, K.D., Franke, T.F. & Holbrook, N.J. Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival. J. Biol. Chem. 275, 14624–14631 (2000).
    Article CAS Google Scholar
  11. Bucciantini, M. et al. The low _M_r phosphotyrosine protein phosphatase behaves differently when phosphorylated at Tyr131 or Tyr132 by Src kinase. FEBS Lett. 456, 73–78 (1999).
    Article CAS Google Scholar
  12. Nielsen, S.D., Afzelius, P., Ersboll, A.K., Nielsen, J.O. & Hansen, J.E. Expression of the activation antigen CD69 predicts functionality of in vitro expanded peripheral blood mononuclear cells (PBMC) from healthy donors and HIV-infected patients. Clin. Exp. Immunol. 114, 66–72 (1998).
    Article CAS Google Scholar
  13. Risso, A. et al. CD69 in resting and activated T lymphocytes. Its association with a GTP binding protein and biochemical requirements for its expression. J. Immunol. 146, 4105–4114 (1991).
    CAS PubMed Google Scholar
  14. Fukuchi, K. et al. Phosphatidylinositol 3-kinase inhibitors, Wortmannin or LY294002, inhibited accumulation of p21 protein after gamma-irradiation by stabilization of the protein. Biochim. Biophys. Acta 1496, 207–220 (2000).
    Article CAS Google Scholar
  15. Duncia, J.V. et al. MEK inhibitors: the chemistry and biological activity of U0126, its analogs and cyclization products. Bioorg. Med. Chem. Lett. 8, 2839–2844(1998).
    Article CAS Google Scholar
  16. Favata, M.F. et al. Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J. Biol. Chem. 273, 18623–18632 (1998).
    Article CAS Google Scholar
  17. DeSilva, D.R. et al. Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy. J. Immunol. 160, 4175–4181 (1998).
    CAS PubMed Google Scholar
  18. Eyers, P.A., Craxton, M., Morrice, N., Cohen, P. & Goedert, M. Conversion of SB 203580-insensitive MAP kinase family members to drug-sensitive forms by a single amino-acid substitution. Chem. Biol. 5, 321–328 (1998).
    Article CAS Google Scholar
  19. Bennecib, M., Gong, C., Grundke-Iqbal, I. & Iqbal, K. Role of protein phosphatase-2A and -1 in the regulation of GSK-3, cdk5 and cdc2 and the phosphorylation of tau in rat forebrain. FEBS Lett. 485, 87–93 (2000).
    Article CAS Google Scholar
  20. Breittmayer, J.P., Pelassy, C. & Aussel, C. Effect of membrane potential on phosphatidylserine synthesis and calcium movements in control and CD3-activated Jurkat T cells. J. Lipid Mediat. Cell Signal. 13, 151–161 (1996).
    Article CAS Google Scholar
  21. Kiss, Z., Phillips, H. & Anderson, W.H. The bisindolylmaleimide GF 109203X, a selective inhibitor of protein kinase C, does not inhibit the potentiating effect of phorbol ester on ethanol-induced phospholipase C-mediated hydrolysis of phosphatidylethanolamine. Biochim. Biophys. Acta 1265, 93–95 (1995).
    Article Google Scholar
  22. Uddin, S., Chamdin, A. & Platanias, L.C. Interaction of the transcriptional activator Stat-2 with the type I interferon receptor. J. Biol. Chem. 270, 24627–24630 (1995).
    Article CAS Google Scholar
  23. Rolli-Derkinderen, M. & Gaestel, M. p38/SAPK2-dependent gene expression in Jurkat T cells. Biol. Chem. 381, 193–198 (2000).
    Article CAS Google Scholar

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