Use of the nirB Promoter to Direct the Stable Expression of Heterologous Antigens in Salmonella Oral Vaccine Strains: Development of a Single–Dose Oral Tetanus Vaccine (original) (raw)

References

1. Germanier, R. and Furer, E. 1975. Isolation and characterisation galE mutant Ty2la of Satrnvnella typhi: a candidate strain for a live oral tvphoid vaccine. J. Infect. Dis. 131: 553–558.
   Article CAS PubMed Google Scholar
2. Levine, M.M., Fericcio, C., Black, R.K., Germanicr, R. and Chilean Typhoid Committee 1987. Large scale field trial of Ty21a live oral typhoid vaccine in enteric coated capsule formulation. Lancet (i): 1049–1052.
   Article Google Scholar
3. Hoiseth, S.K. and Stocker, B.A.D. 1981. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 291: 238–240.
   Article CAS PubMed Google Scholar
4. O'Callaghan, D., Maskell, D., Liew, F.Y., Easmon, C.S.F. and Dougan, G. 1988. Characterisation of aromatic- and purine-dependent Salmonella typhimurium: attenuation, persistence, and ability to induce protective immunity in BALB/c mice. Infect. Immun. 56: 419–426.
   CAS PubMed PubMed Central Google Scholar
5. Mukkur, T.K.S., McDowell, G.N., Stocker, B.A.D. and Lascelles, A.K. 1987. Protection against saimonellosis in mice and sheep by immunisation with aromatic-dependent Salmonella typhimurium . J. Med. Microbiol. 24: 11–19.
   Article CAS PubMed Google Scholar
6. Jones, P.W., Dougan, G., Hayward, C., Mackensie, N., Collins, P. and Chatfield, S.N. 1991. Oral vaccination of calves against experimental salmonellosis using a double aro mutant of Salmonella typhimurium . Vaccine 9: 29–36.
   Article CAS PubMed Google Scholar
7. Casper, G.L., Nicholas, R.A.J., Cullen, G.A. and Hormache, C.E. 1990. Vaccination of chickens with a Salmonella ententidis aroA live oral Salmonella vaccine. Microbiol. Pathogen. 9: 255–265.
   Article Google Scholar
8. Dougan, G., Hofnung, M., Lanzavecchia, A. and Leclerc, C. Immune response to proteins with recombinant epitopes, perspectives for vaccines, p. 171–220. In: Conferences Philipe Laudat 1990 INSERM, Paris.
   Google Scholar
9. Newton, S.M.C., Jacob, C.O. and Stocker, B.A.D. 1989. Immune response to cholera toxin epitope inserted in Salmonella flagellin. Science 244: 70–72.
   Article CAS PubMed Google Scholar
10. Tite, J.P., Gao, X.M., Hughes Jenkins, M., Lipscombe, M., O'Callaghan, D., Dougan, G. and Liew, F.Y. 1990. Anti-viral immunity induced by recombinant nucleoprotein of Influenza A virus. III. Delivery of recombinant nucleoprotein to the immune system using attenuated Salmonella typhimurium as a liver carrier. Immunology 70: 540–547.
    CAS PubMed PubMed Central Google Scholar
11. Sadoff, J.C., Ballou, W.R., Baron, L.S., Majarian, W.R., Brey, R.N., Hockmeyer, W.T., Young, J.F., Cryz, J.J., Ou, J., Lowell, G.H. and Chulay, J.D. 1988. Oral Salmonella typhimurium vaccine expressing circumsporozoite protein protects against malaria. Science 240: 236–238.
    Article Google Scholar
12. Fairweather, N.F., Chatfield, S.N., Makoff, A.J., Strugnell, R.A., Bester, J., Maskell, D.J. and Dougan, G. 1990. Oral vaccination of mice against tetanus by use of a live attenuated Salmonella carrier. Infect. Immun. 58: 1323–1329.
    CAS PubMed PubMed Central Google Scholar
13. Chatfield, S.N., Fairweather, N.F., Charles, I., Pickard, D., Levine, M., Hone, D., Posada, M., Strugnell, R.A. and Dougan, G. 1992. Construction of a genetically defined Salmonella typhi Ty2 aroA, aroC mutant for the engineering of a candidate oral typhoid-tetanus vaccine. Infect. Immun: 10: 53–60.
    CAS Google Scholar
14. Stanfield, J.P. and Galazka, A. 1984. Neonatal tetanus in the third world today. Bull. WHO 62: 647–669.
    CAS PubMed PubMed Central Google Scholar
15. Amann, E., Brosius, J. and Ptashne, M. 1983. Vectors bearing a hybrid trp-lac promoter useful for regulated expression of cloned genes in Escherichia coli . Gene 25: 167–178.
    Article CAS PubMed Google Scholar
16. Peakman, T., Crouzet, J., Jayaux, J.F., Busby, S., Mohan, S., Harborne, N., Wooton, J., Nicholson, R. and Cole, J. 1990. Nucleotide sequence, organisation and structural analysis of the products of genes in the nirB-cysB region of the Escherichia coli K-12 chromosome. Eur. J. Biochem. 191: 315–323.
    Article CAS PubMed Google Scholar
17. Oxer, M.D., Bently, C.M., Doyle, J.G., Peakman, T.C., Charles, I.G. and Makoff, A.J. 1991. High level heterologous expression in E. coli. using the anaerobically-activated nirB promoter. Nucl. Acids Res. 19: 1889–1892.
    Article Google Scholar
18. Bullas, L.R. and Ryu, J.I. 1983. Salmonella typhimurium LT2 strains which are r-m+ for all three chromosomally located systems of DNA restriction and modification. J. Bacteriol. 156: 471–474.
    CAS PubMed PubMed Central Google Scholar
19. Hone, D., Attridge, S. Van den Bosch, L. and Hackett, J. 1988. A chromosomal integration system tor stabilisation of heterologous genes in Salmonella based vaccine strains. Microbial Pathogen. 5: 407–418.
    Article CAS Google Scholar
20. Nakayama, K., Kelly, S.M. and Curtiss, R. 1988. Construction of an Asd expression-cloning vector: stable maintenance and high levels expression of cloned genes in a Salmonella vaccine strain. Bio/Technology 6: 693–697.
    CAS Google Scholar
21. Strugnell, R.A., Maskell, D., Fairweather, N., Pickard, D., Cockayne, A., Penn, C. and Dougan, G. 1990. Stable expression of foreign antigens from the chromosome of Salmonella typhimurium vaccine strains. Gene 88: 57–63.
    Article CAS PubMed Google Scholar
22. Jayaraman, P.S., Peakman, T.C., Busby, S.J.W., Quincey, R.V. and Cole, J.A. 1987. Location and sequence of the promoter of the gene for the NADH-dependent nitrite reductase of Escherichia coli and its regulation by oxygen, the Fnr protein and nitrite. J. Mol. Biol. 196: 781–788.
    Article CAS PubMed Google Scholar
23. Bell, A.I., Gaston, K.L., Cole, J.A. and Busby, S.J.W. 1989. Cloning of binding sequences for the Escherichia coli transcription activators, FNR and CRP: location of bases involved in discrimination between FNR and CRP. Nucl. Acids Res. 17: 3865–3874.
    Article CAS PubMed PubMed Central Google Scholar
24. Jayaraman, P.S., Cole, J.A. and Busby, S.J.W. 1989. Mutational analysis of the nucleotide sequence at the FNR-depeiident nirB promoter in Escherichia coli . Nucl. Acids Res. 17: 135–145.
    Article CAS PubMed PubMed Central Google Scholar
25. Stover, C.K., de la Cruz, V.F., Fuerst, T.R., Burlein, J.E., Benson, L.A., Bennet, L.T., Bansal, G.P., Young, J.F., Lee, M.H., Hatful, G.F., Snapper, S.B., Barletta, R.G., Jacobs, W.R. and Bloom, B.R. 1991. New use of BCG for recombinant vaccines. Nature 351: 456–460.
    Article CAS PubMed Google Scholar
26. Davis, R.W., Bostein, D. and Roth, J.R. 1980. Advanced Bacterial Genet ics. A Manual for Genetic Engineering. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
    Google Scholar
27. Makoff, A.J., Oxer, M.D., Romanos, M.A., Fairweather, N.F. and Ballantine, S. 1989. Expression of tetanus toxin fragment C. in E. coli: high level expression by removing rare codons. Nucl. Acids Res. 17: 10191–10202.
    Article CAS PubMed PubMed Central Google Scholar

Download references