Peptide modulators of protein–protein interactions in intracellular signaling (original) (raw)
References
Pawson, T. and Scott, J.D. 1997. Signaling through scaffold, anchoring, and adaptor proteins. Science278: 2075–2080. ArticleCASPubMed Google Scholar
Hubbard, M.J. and Cohen, P. 1993. On target with a new mechanism for the regulation of protein phosphorylation. TIBS18: 172–177. CASPubMed Google Scholar
Mochly-Rosen, D., Smith, B.L., Chen, C.H., Disatnik, M.H. and Ron, D. 1995. Interaction of protein kinase C with RACK1, a receptor for activated C-kinase: a role in beta protein kinase C mediated signal transduction. Biochem. Soc. Trans.23: 596–600. ArticleCASPubMed Google Scholar
Koch, W.J., Inglese, J., Stone, W.C. and Lefkowitz, R.J. 1993. The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J. Biol. Chem.268: 8256–8260. CASPubMed Google Scholar
Pitcher, J.A., Inglese, J., Higgins, J.B., Arriza, J.L., Casey, P.J., Kim, C. et al. 1992. Role of βγ subunits of G proteins in targeting the b-adrenergic receptor kinase to membrane-bound receptors. Science257: 1264–1267. ArticleCASPubMed Google Scholar
Boekhoff, I., Inglese, J., Schleicher, S., Koch, W.J., Lefkowitz, R.J. and Breer, H. 1994. Olfactory desensitization requires membrane targeting of receptor kinase mediated by beta gamma-subunits of heterotrimeric G proteins. J. Biol. Chem.269: 37–40. CASPubMed Google Scholar
Scott, J.K. and Smith, G.P. 1990. Searching for peptide ligands with an epitope library. Science249: 386–390. ArticleCASPubMed Google Scholar
Wu, J., Ma, Q.N. and Lam,K.S. 1994. Identifying substrate motifs of protein kinases by a random library approach. Biochemistry33: 14825–14833. ArticleCASPubMed Google Scholar
Nishi, T., Budde,R.J., McMurray, J.S., Obeyesekere, N.U., Safdar, N., Levin, V.A. et al. 1996. Tight-binding inhibitory sequences against pp60(c-src) identified using a random 15-amino-acid peptide library. FEBS Lett399: 237–240. ArticleCASPubMed Google Scholar
Nevalainen, L.T., Aoyama, T., Ikura, M., Crivici, A., Yan, H., Chua, N.H. et al. 1997 Characterization of novel calmodulin-binding peptides with distinct inhibitory effects on calmodulin-dependent enzymes. Biochem. J.321: 107–115. ArticleCASPubMedPubMed Central Google Scholar
Fantl, W.J., Escobedo, J.A., Martin, G.A., Turck, C.W., del Rosario, M., McCormick, F. et al. 1992. Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways. Cell69: 413–423. ArticleCASPubMed Google Scholar
Alonso, G., Koegl, M., Mazurenko, N. and Courtneidge, S.A. 1995. Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors. J. Biol. Chem.270: 9840–9848. ArticleCASPubMed Google Scholar
Wange, R.L., Isakov, N., Burke, T.R.Jr., Otaka, A., Roller, P.P., Watts, J.D. et al. 1995. F2(Pmp)2-TAM zeta 3, a novel competitive inhibitor of the binding of ZAP- 32. 70 to the T cell antigen receptor, blocks early T cell signaling. J. Biol. Chem.270: 944–948. ArticleCASPubMed Google Scholar
Songyang, Z., Shoelson,S.E., Chaudhuri, M., Gish, G., Pawson, T., Haser,W.G. et al. 1993. SH2 domains recognize specific phosphopeptide sequences. Cell72: 767–778. ArticleCASPubMed Google Scholar
Yaffe, M.B., Rittinger, K., Volinia, S., Caron, P.R., Aitken, A., Leffers,H. et al.1997. The structural basis for 14-3-3:phosphopeptide binding specificity. Cell91: 961–971. ArticleCASPubMed Google Scholar
Songyang, Z., Fanning, A.S., Fu, C., Xu,J., Marfatia, S.M., Chishti, A.H et al. 1997. Recognition of unique carboxyl-terminal motifs by distinct PDZ domains. Science275: 73–77. ArticleCASPubMed Google Scholar
Grabs, D., Slepnev, V.I., Songyang, Z., David, C., Lynch, M., Cantley, L.C. et al. 1997. The SH3 domain of amphiphysin binds the proline-rich domain of dynaminat a single site that defines a new SH3 binding consensus sequence. J. Biol. Chem.272: 13419–13425. ArticleCASPubMed Google Scholar
Nishikawa, K., Toker, A., Johannes, F.J., Songyang, Z., and Cantley, L.C. 1997. Determination of the specific substrate sequence motifs of protein kinase C isozymes. J. Biol. Chem.272: 952–960. ArticleCASPubMed Google Scholar
Rickles, R.J., Botfield, M.C., Zhou, X.M., Henry, P.A., Brugge, J.S., and Zoller, M.J. 1995. Phage display selection of ligand residues important for Src homolo-gy 3 domain binding specificity. Proc. Natl. Acad. Sci. USA92: 10909–10913. ArticleCASPubMedPubMed Central Google Scholar
Schmitz, R., Baumann, G. and Gram, H. 1996. Catalytic specificity of phospho-tyrosine kinases Blk, Lyn, c-Src and Syk as assessed by phage display. J. Mol. Biol.260: 664–677. ArticleCASPubMed Google Scholar
Alexandropoulos, K., Cheng, G. and Baltimore, D. 1995. Proline-rich sequencesthat bind to Src homology 3 domains with individual specificities. Proc. Natl. Acad. Sci. USA92: 3110–3114. ArticleCASPubMedPubMed Central Google Scholar
Stauffer, T.R., Martenson, C.H., Rider, J.E., Kay, B.K., and Meyer, T. 1997. Inhibition of Lyn function in mast cell activation by SH3 peptides. Biochemistry36: 9388–9394. ArticleCASPubMed Google Scholar
Carr, D.W., Hausken, Z.E., Fraser, I.D., Stofko-Hahn, R.E., and Scott, J.D. 1992. Association of the type II cAMP-dependent protein kinase with a human thyroid Rll-anchoring protein. Cloning and characterization of the Rll-binding domain. J. Biol. Chem.267: 13376–13382. Google Scholar
Hirsch, A.H., Glantz,S.B., Li, Y., You,Y., and Rubin, C.S. 1992. Cloning and expression of an intron-less gene for AKAP 75, an anchor protein for the regulatory subunit of cAMP-dependent protein kinase II beta. J. Biol. Chem.267: 2131–2134. CASPubMed Google Scholar
Carr, D.W., Stofko-Hahn, R.E., Fraser, I.D., Cone, R.D., and Scott, J.D. 1992. Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79.J. Biol. Chem.267: 16816–16823. Google Scholar
Lester, L.B., Langeberg, L.K., and Scott, J.D. 1997. Anchoring of protein kinase A facilitates hormone-mediated insulin secretion. Proc. Natl. Acad. Sci. USA94: 14942–14947. ArticleCASPubMedPubMed Central Google Scholar
Vijayaraghavan, S., Goueli, S.A., Davey, M.P., and Carr, D.W. 1997. Protein kinase A-anchoring inhibitor peptides arrest mammalian sperm motility. J. Biol. Chem.272: 4747–4752. ArticleCASPubMed Google Scholar
Rosenmund C., Carr, D.W., Bergeson, S.E., Nilaver, G., Scott, J.D., and Westbrook, G.L 1994. Anchoring of protein kinase A is required for modulation of AMPA/kainate receptors on hippocampal neurons. Nature368: 853–856. ArticleCASPubMed Google Scholar
Aitken, A., Ellis, C.A., Harris, A., Sellers, L.A., and Toker, A. 1990. Kinase and neu-rotransmitters [letter]. Nature344: 594. ArticleCASPubMed Google Scholar
Mochly-Rosen, D., Khaner, H., and Lopez, J. 1991. Identification of intracellular receptor proteins for activated protein kinase C. Proc. Natl. Acad. Sci. USA88: 3997–4000. ArticleCASPubMedPubMed Central Google Scholar
Ron, D. and Mochly-Rosen, D. 1994. Agonists and antagonists of protein kinase C function, derived from its binding proteins. J. Biol. Chem.269: 21395–21398. CASPubMed Google Scholar
Mochly-Rosen, D., Miller, K.G., Scheller, R.H., Lopez, J., and Smith, B.L. 1992. p65 fragments, homologous to the C2 region of protein kinase C, bind to the intracellular receptors for protein kinase C. Biochemistry31: 8120–8124. ArticleCASPubMed Google Scholar
Disatnik, M.H., Hernandez-Sotomayor, S.M., Jones, G., Carpenter, G., and Mochly-Rosen, D. 1994. Phospholipase C-gamma 1 binding to intracellular receptors for activated protein kinase C. Proc. Natl. Acad. Sci. USA91: 559–563. ArticleCASPubMedPubMed Central Google Scholar
Ron, D., Luo, J., and Mochly-Rosen, D. 1995. C2 region-derived peptides inhibit translocation and function of beta protein kinase C in vivo. J. Biol. Chem.270: 24180–24187. ArticleCASPubMed Google Scholar
Yedovitzky, M., Mochly-Rosen, D., Johnson, J.A., Gray, M.O., Ron, D., Abramovitch, E. et al. 1997. Translocation inhibitors define specificity of protein kinase C isoenzymes in pancreatic beta-cells. J. Biol. Chem.272: 1417–1420. ArticleCASPubMed Google Scholar
Zhang, Z.H., Johnson, J.A., chen, L., El-Sherif, N., Mochly-Rosen, D., and Boutjdir, M. 1997. C2 region-derived peptides of beta-protein kinase C regulate cardiac Ca2+ channels. Circ. Res.80: 720–729. ArticleCASPubMed Google Scholar
Johnson, J.A., Gray, M.O., Chen, C.H., and Mochly-Rosen, D. 1996. A protein kinase C translocation inhibitor as an isozyme-selective antagonist of cardiac function. J. Biol. Chem.271: 24962–24966. ArticleCASPubMed Google Scholar
Sossin, W.S. and Schwartz, J.H. 1993. Ca2+−independent protein kinase Cs contain an amino-terminal domain similar to the C2 consensus sequence. TIBS18: 207–208. CASPubMed Google Scholar
Gray, M.O., Karliner, J.S., and Mochly-Rosen, D. 1997. A selective epsilon-pro-tein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death. J. Biol. Chem.272: 30945–30951. ArticleCASPubMed Google Scholar
Kobe, B., Heierhorst, J., and Kemp, B.E. 1997. Intrasteric regulation of protein kinases. Adv. Second Messenger Phosphoprotein Res.31: 29–40. ArticleCASPubMed Google Scholar
Ron, D., Chen, C.H., Caldwell, J., Jamieson L., Orr, E., and Mochly-Rosen, D. 1994. Cloning of an intracellular receptor for protein kinase C: a homolog of the beta subunit of G proteins Proc. Natl. Acad. Sci. USA91: 839–843.[published erratum appears 1995, _Proc. Natl. Acad. Sci. USA_ **92**:2016. ArticleCASPubMedPubMed Central Google Scholar
Ron, D. and Mochly-Rosen, D. 1995. An autoregulatory region in protein kinase C: the seudoanchoring site. Proc. Natl. Acad. Sci. USA92: 492–496. ArticleCASPubMedPubMed Central Google Scholar
Johnson, J.A., Gray, M.O., Karliner, J.S., Chen, C.H., and Mochly-Rosen, D. 1996. An improved permeabilization protocol for the introduction of peptides into cardiac myocytes. Application to protein kinase C research. Circ. Res.79: 1086–1099. ArticleCASPubMed Google Scholar
O'Brian, C.A., Ward, N.E., Liskamp, R.M., de Bont, D., Earnest, L.E., van Boom, J.H. et al. 1991. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to adriamycin. Inest. New Drugs9: 169–179. ArticleCAS Google Scholar
Verhoeven, A.J., Leusen, J.H., Kessels, G.C., Hilarius, P.M., de Bont, D.B., and Liskamp, R.M. 1993. Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C. J. Biol. Chem.268: 18593–18598. CASPubMed Google Scholar
Theodore, L., Derossi, D., Chassaing, G., Llirbat, B., Kubes, M., Jordan, P. et al. 1995. Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse. J. Neurosci.15: 7158–7167. ArticleCASPubMedPubMed Central Google Scholar
Derossi, D., Joliot, A.H., Chassaing, G., and Prochiantz, A. 1994. The third helixof the Antennapedia homeodomain translocates through biological membranes. J. Biol. Chem.269: 10444–10450. CASPubMed Google Scholar
Mochly-Rosen, D., Khaner, H., Lopez, J., and Smith, B.L. 1991. Intracellular receptors for activated protein kinase C. Identification of a binding site for the enzyme. J.Biol. Chem.266: 14866–14868. Google Scholar
Pooga, M., Soomets, U., Hallbrink, M., Valkna, A., Saar, K., Rezaei, K. et al. 1998. Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo. Nat. Biotechnol.16: 857–861. ArticleCASPubMed Google Scholar