Hsp90 invades the outside (original) (raw)
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- Published: 01 June 2004
Nature Cell Biology volume 6, pages 479–480 (2004)Cite this article
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Metalloproteases are required for the invasive nature of cancer cells. Surprisingly, the cytosolic molecular chaperone Hsp90 is now shown to promote maturation of the extracellular metalloprotease MMP2. This finding extends the multiplicity of roles assigned to the Hsp90 family to a new function outside the cell.
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Figure 1: The Hsp90 connection.
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- Département de Biologie Cellulaire, Université de Genève, Sciences III, 30, quai Ernest-Ansermet, Genève, 4, CH - 1211, Switzerland
Didier Picard
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- Didier Picard
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Picard, D. Hsp90 invades the outside.Nat Cell Biol 6, 479–480 (2004). https://doi.org/10.1038/ncb0604-479
- Issue Date: 01 June 2004
- DOI: https://doi.org/10.1038/ncb0604-479