MAP kinase dynamics in response to pheromones in budding yeast (original) (raw)
References
Cobb, M. H. MAP kinase pathways. Prog. Biophys. Mol. Biol.71, 479–500 (1999). ArticleCAS Google Scholar
Whitmarsh, A. J. & Davis, R. J. Structural organization of MAP-kinase signalling modules by scaffold proteins in yeast and mammals. Trends Biochem. Sci.23, 481–485 (1998). ArticleCAS Google Scholar
Schaeffer, H. J. & Weber, M. J. Mitogen-activated protein kinases: specific messages from ubiquitous messengers. Mol. Cell Biol.19, 2435–2444 (1999). ArticleCAS Google Scholar
Elion, E. A. Pheromone response, mating and cell biology. Curr. Opin. Microbiol.3, 573–581 (2000). ArticleCAS Google Scholar
Dohlmanm, H. & Thorner, J. Regulation of G protein-initiated signal transduction in yeast: paradigms and principles. Annu. Rev. Biochem.70, 703–754 (2001). Article Google Scholar
Whiteway, M. S. et al. Association of the yeast pheromone response G protein beta gamma subunits with the MAP kinase scaffold Ste5p. Science269, 1572–1575 (1995). ArticleCAS Google Scholar
Leeuw, T. et al. Interaction of a G-protein beta-subunit with a conserved sequence in Ste20/PAK family protein kinases. Nature391, 191–195 (1998). ArticleCAS Google Scholar
Choi, K. Y., Satterberg, B., Lyons, D. M. & Elion, E. A. Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae. Cell78, 499–512 (1994). ArticleCAS Google Scholar
Kranz, J. E., Satterberg, B. & Elion, E. A. The MAP kinase Fus3 associates with and phosphorylates the upstream signalling component Ste5. Genes Dev.8, 313–327 (1994). ArticleCAS Google Scholar
Marcus, S., Polverino, A., Barr, M. & Wigler, M. Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc. Natl Acad. Sci. USA91, 7762–7766 (1994). ArticleCAS Google Scholar
Cook, J. G., Bardwell, L., Kron, S. J. & Thorner, J. Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes Dev.10, 2831–2848 (1996). ArticleCAS Google Scholar
Tedford, K., Kim, S., Sa, D., Stevens, K. & Tyers, M. Regulation of the mating pheromone and invasive growth responses in yeast by two MAP kinase substrates. Curr. Biol.7, 228–238 (1997). ArticleCAS Google Scholar
Gustin, M. C., Albertyn, J., Alexander, M. & Davenport, K. MAP kinase pathways in the yeast Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev.62, 1264–1300 (1998). CASPubMedPubMed Central Google Scholar
Levin, D. E. & Errede, B. The proliferation of MAP kinase signalling pathways in yeast. Curr. Opin. Cell Biol.7, 197–202 (1995). ArticleCAS Google Scholar
Posas, F. & Saito, H. Osmotic activation of the HOG MAPK pathway via Ste11p MAPKKK: scaffold role of Pbs2p MAPKK. Science276, 1702–1705 (1997). ArticleCAS Google Scholar
Madhani, H. D. & Fink, G. R. The riddle of MAP kinase signalling specificity. Trends Genet.14, 151–155 (1998). ArticleCAS Google Scholar
Ferrigno, P., Posas, F., Koepp, D., Saito, H. & Silver, P. A. Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J.17, 5606–5614 (1998). ArticleCAS Google Scholar
Peter, M., Neiman, A. M., Park, H. O., vanLohuizen, M. & Herskowitz, I. Functional Analysis of the interaction between the small GTP-binding protein Cdc42 and the Ste20 protein kinase in yeast. EMBO J.15, 7046–7059 (1996). ArticleCAS Google Scholar
Leberer, E. et al. Functional characterization of the Cdc42p-binding domain of yeast Ste20p protein kinase. EMBO J.16, 83–97 (1997). ArticleCAS Google Scholar
Pryciak, P. M. & Huntress, F. A. Membrane recruitment of the kinase cascade scaffold protein Ste5 by the G beta gamma complex underlies activation of the yeast pheromone response pathway. Genes Dev.12, 2684–2697 (1998). ArticleCAS Google Scholar
Mahanty, S. K., Wang, Y., Farley, F. W. & Elion, E. A. Nuclear shuttling of yeast scaffold Ste5 is required for its recruitment to the plasma membrane and activation of the mating MAPK cascade. Cell98, 501–512 (1999). ArticleCAS Google Scholar
Choi, K. Y., Kranz, J. E., Mahanty, S. K., Park, K. S. & Elion, E. A. Characterization of Fus3 localization: active Fus3 localizes in complexes of varying size and specific activity. Mol. Biol. Cell10, 1553–1568 (1999). ArticleCAS Google Scholar
Khokhlatchev, A. V. et al. Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Cell93, 605–615 (1998). ArticleCAS Google Scholar
Adachi, M., Fukuda, M. & Nishida, E. Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer. EMBO J.18, 5347–5358 (1999). ArticleCAS Google Scholar
Gaits, F., Degols, G., Shiozaki, K. & Russell, P. Phosphorylation and association with the transcription factor Atf1 regulate localization of Spc1/Sty1 stress-activated kinase in fission yeast. Genes Dev.12, 1464–1473 (1998). ArticleCAS Google Scholar
Mattison, C. P. & Ota, I. M. Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast. Genes Dev.14, 1229–1235 (2000). CASPubMedPubMed Central Google Scholar
Fukuda, M., Gotoh, Y. & Nishida, E. Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase. EMBO J.16, 1901–1908 (1997). ArticleCAS Google Scholar
Inouye, C., Dhillon, N., Durfee, T., Zambryski, P. C. & Thorner, J. Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions. Genetics147, 479–492 (1997). CASPubMedPubMed Central Google Scholar
White, J. & Stelzer, E. Photobleaching GFP reveals protein dynamics inside live cells. Trends Cell Biol.9, 61–65 (1999). ArticleCAS Google Scholar
Gorlich, D. & Kutay, U. Transport between the cell nucleus and the cytoplasm. Annu. Rev. Cell Dev. Biol.15, 607–660 (1999). ArticleCAS Google Scholar
Blondel, M. et al. Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev.13, 2284–2300 (1999). ArticleCAS Google Scholar
Oehlen, B. & Cross, F. R. Signal transduction in the budding yeast Saccharomyces cerevisiae. Curr. Opin. Cell Biol.6, 836–841 (1994). ArticleCAS Google Scholar
Gartner, A., Nasmyth, K. & Ammerer, G. Signal transduction in Saccharomyces cerevisiae requires tyrosine and threonine phosphorylation of FUS3 and KSS1. Genes Dev.6, 1280–1292 (1992). ArticleCAS Google Scholar
van Drogen, F., O'Rourke, S., Stucke, V., Jaquenoud, M. & Peter, M. Phosphorylation of the MEKK Ste11p by the PAK-like kinase Ste20p is required for MAP kinase signalling in vivo. Curr. Biol.10, 630–639 (2000). ArticleCAS Google Scholar
Doi, K. et al. MSG5, a novel protein phosphatase promotes adaptation to pheromone response in S. cerevisiae. EMBO J.13, 61–70 (1994). ArticleCAS Google Scholar
Garrison, T. R. et al. Feedback phosphorylation of an RGS protein by MAP kinase in yeast. J. Biol. Chem.274, 36387–36391 (1999). ArticleCAS Google Scholar
Sharrocks, A. D., Yang, S. H. & Galanis, A. Docking domains and substrate-specificity determination for MAP kinases. Trends Biochem. Sci.25, 448–453 (2000). ArticleCAS Google Scholar
Sette, C., Inouye, C. J., Stroschein, S. L., Iaquinta, P. J. & Thorner, J. Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Mol. Biol. Cell11, 4033–4049 (2000). ArticleCAS Google Scholar
Feng, Y., Song, L. Y., Kincaid, E., Mahanty, S. K. & Elion, E. A. Functional binding between Gβ and the LIM domain of Ste5 is required to activate the MEKK Ste11. Curr. Biol.8, 267–278 (1998). ArticleCAS Google Scholar
Moskow, J. J., Gladfelter, A. S., Lamson, R. E., Pryciak, P. M. & Lew, D. J. Role of Cdc42p in pheromone-stimulated signal transduction in Saccharomyces cerevisiae. Mol. Cell Biol.20, 7559–7571 (2000). ArticleCAS Google Scholar
Reiser, V., Salah, S. M. & Ammerer, G. Polarized localization of yeast Pbs2 depends on osmostress, the membrane protein Sho1 and Cdc42. Nature Cell Biol.2, 620–627 (2000). ArticleCAS Google Scholar
Raitt, D. C., Posas, F. & Saito, H. Yeast Cdc42 GTPase and Ste20 PAK-like kinase regulate Sho1-dependent activation of the Hog1 MAPK pathway. EMBO J.19, 4623–4631 (2000). ArticleCAS Google Scholar
Guthrie, C. & Fink, G. R. Guide to Yeast Genetics and Molecular Biology (Academic, San Diego, 1991)). Google Scholar
Ausubel, F. M. et al. Current Protocols in Molecular Biology (Greene and Wiley-Interscience, New York, 1991). Google Scholar
Jaquenoud, M., Gulli, M. P., Peter, K. & Peter, M. The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex. EMBO J.17, 5360–5373 (1998). ArticleCAS Google Scholar
Valtz, N. & Peter, M. Functional analysis of FAR1 in yeast. Methods Enzymol.283, 350–365 (1997). ArticleCAS Google Scholar
Brown, J. L., Jaquenoud, M., Gulli, M. P., Chant, J. & Peter, M. Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev.11, 2972–2982 (1997). ArticleCAS Google Scholar
Gulli, M. et al. Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast. Mol. Cell6, 1155–1167 (2000). ArticleCAS Google Scholar
Ellenberg, J. & Lippincott-Schwartz, J. in Cells: A Laboratory Manual (eds Spector, D., Goldman, R. & Leinwand, L.) 79.1–79.23 (Cold Spring Harbor Laboratory Press, 1998). Google Scholar