Reduced cytosolic protein synthesis suppresses mitochondrial degeneration (original) (raw)
References
Wallace, D. C. A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine. Annu. Rev. Genet.39, 359–407 (2005). ArticleCAS Google Scholar
Spinazzola, A. & Zeviani, M. Disorders of nuclear-mitochondrial intergenomic signaling. Gene354, 162–168 (2005). ArticleCAS Google Scholar
Suomalainen, A. & Kaukonen, J. Diseases caused by nuclear genes affecting mtDNA stability. Am. J. Med. Genet.106, 53–61 (2001). ArticleCAS Google Scholar
Kaukonen, J. et al. Role of adenine nucleotide translocator 1 in mtDNA maintenance. Science289, 782–785 (2000). ArticleCAS Google Scholar
Esposito, L. A., Melov, S., Panov, A., Cottrell, B. A. & Wallace, D. C. Mitochondrial disease in mouse results in increased oxidative stress. Proc. Natl Acad. Sci. USA96, 4820–4825 (1999). ArticleCAS Google Scholar
Fontanesi, F. et al. Mutations in AAC2, equivalent to human adPEO-associated ANT1 mutations, lead to defective oxidative phosphorylation in Saccharomyces cerevisiae and affect mitochondrial DNA stability. Hum. Mol. Genet.13, 923–934 (2004). ArticleCAS Google Scholar
Chen, X. J. Induction of an unregulated channel by mutations in adenine nucleotide translocase suggests an explanation for human ophthalmoplegia. Hum. Mol. Genet.11, 1835–1843 (2002). ArticleCAS Google Scholar
Pebay-Peyroula, E. et al. Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside. Nature426, 39–44 (2003). ArticleCAS Google Scholar
Heidkamper, D., Muller, V., Nelson, D. R. & Klingenberg, M. Probing the role of positive residues in the ADP/ATP carrier from yeast. The effect of six arginine mutations on transport and the four ATP versus ADP exchange modes. Biochemistry35, 16144–16152 (1996). ArticleCAS Google Scholar
Fabrizio, P., Pletcher, S. D., Minois, N., Vaupel, J. W. & Longo, V. D. Chronological aging-independent replicative life span regulation by Msn2/Msn4 and Sod2 in Saccharomyces cerevisiae. FEBS Lett.557, 136–142 (2004). ArticleCAS Google Scholar
Kaeberlein, M. et al. Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients. Science310, 1193–1196 (2005). ArticleCAS Google Scholar
Steffen, K. K. et al. Yeast life span extension by depletion of 60S ribosomal subunit is mediated by Gcn4. Cell133, 292–302 (2008). ArticleCAS Google Scholar
Lin, S. J., Defossez, P. A. & Guarente, L. Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science289, 2126–2128 (2000). ArticleCAS Google Scholar
Sinclair, D. A. & Guarente, L. Extrachromosomal rDNA circles — a cause of aging in yeast. Cell91, 1033–1042 (1997). ArticleCAS Google Scholar
Defossez, P. A. et al. Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol. Cell3, 447–455 (1999). ArticleCAS Google Scholar
Lebreton, A. et al. A functional network involved in the recycling of nucleocytoplasmic pre-60S factors. J. Cell Biol.173, 349–360 (2006). ArticleCAS Google Scholar
Jiang, J. C., Jaruga, E., Repnevskaya, M. V. & Jazwinski, S. M. An intervention resembling caloric restriction prolongs life span and retards aging in yeast. FASEB J.14, 2135–2137 (2000). ArticleCAS Google Scholar
Rinnerthaler, M. et al. MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria. Biochim. Biophys. Acta1757, 631–638 (2006). ArticleCAS Google Scholar
Kim, S., Benguria, A., Lai, C. Y. & Jazwinski, S. M. Modulation of life-span by histone deacetylase genes in Saccharomyces cerevisiae. Mol Biol Cell10, 3125–3136 (1999). ArticleCAS Google Scholar
Fleischer, T. C., Weaver, C. M., McAfee, K. J., Jennings, J. L. & Link, A. J. Systematic identification and functional screens of uncharacterized proteins associated with eukaryotic ribosomal complexes. Genes Dev.20, 1294–1307 (2006). ArticleCAS Google Scholar
Meskauskas, A. et al. Delayed rRNA processing results in significant ribosome biogenesis and functional defects. Mol. Cell Biol.23, 1602–1613 (2003). ArticleCAS Google Scholar
Lai, C. Y., Jaruga, E., Borghouts, C. & Jazwinski, S. M. A mutation in the ATP2 gene abrogates the age asymmetry between mother and daughter cells of the yeast Saccharomyces cerevisiae. Genetics162, 73–87 (2002). CASPubMedPubMed Central Google Scholar
Coates, P. J., Jamieson, D. J., Smart, K., Prescott, A. R. & Hall, P. A. The prohibitin family of mitochondrial proteins regulate replicative lifespan. Curr. Biol.7, 607–610 (1997). ArticleCAS Google Scholar
Arnold, I. & Langer, T. Membrane protein degradation by AAA proteases in mitochondria. Biochim. Biophys. Acta1592, 89–96 (2002). ArticleCAS Google Scholar
Chen, J. C., Jiang, C. Z. & Reid, M. S. Silencing a prohibitin alters plant development and senescence. Plant J.44, 16–24 (2005). ArticleCAS Google Scholar
Dunn, C. D., Lee, M. S., Spencer, F. A. & Jensen, R. E. A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol. Biol. Cell17, 213–226 (2006). ArticleCAS Google Scholar
Thorsness, P. E., White, K. H. & Fox, T. D. Inactivation of YME1, a member of the ftsH-SEC18-PAS1-CDC48 family of putative ATPase-encoding genes, causes increased escape of DNA from mitochondria in Saccharomyces cerevisiae. Mol. Cell Biol.13, 5418–5426 (1993). ArticleCAS Google Scholar
Pearce, D. A. & Sherman, F. Degradation of cytochrome oxidase subunits in mutants of yeast lacking cytochrome c and suppression of the degradation by mutation of yme1. J. Biol. Chem.270, 20879–20882 (1995). ArticleCAS Google Scholar
Brand, M. D. et al. The basal proton conductance of mitochondria depends on adenine nucleotide translocase content. Biochem. J.392, 353–362 (2005). ArticleCAS Google Scholar
Miller, R. A. et al. Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell4, 119–125 (2005). ArticleCAS Google Scholar
Lin, S. J. et al. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature418, 344–348 (2002). ArticleCAS Google Scholar
Tong, J. J., Schriner, S. E., McCleary, D., Day, B. J. & Wallace, D. C. Life extension through neurofibromin mitochondrial regulation and antioxidant therapy for neurofibromatosis-1 in Drosophila melanogaster. Nature Genet.39, 476–485 (2007). ArticleCAS Google Scholar
Bonawitz, N. D., Chatenay-Lapointe, M., Pan, Y. & Shadel, G. S. Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression. Cell Metab.5, 265–277 (2007). ArticleCAS Google Scholar
Tavernarakis, N. Ageing and the regulation of protein synthesis: a balancing act? Trends Cell Biol.18, 228–235 (2008). ArticleCAS Google Scholar
Chiocchetti, A. et al. Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span. Exp. Gerontol.42, 275–286 (2007). ArticleCAS Google Scholar