Chromosome- and spindle-pole-derived signals generate an intrinsic code for spindle position and orientation (original) (raw)
Grill, S. W. & Hyman, A. A. Spindle positioning by cortical pulling forces. Dev. Cell8, 461–465 (2005). ArticleCAS Google Scholar
Glotzer, M. The mechanism and control of cytokinesis. Curr. Opin. Cell Biol.9, 815–823 (1997). ArticleCAS Google Scholar
Gonczy, P. Mechanisms of asymmetric cell division: flies and worms pave the way. Nat. Rev. Mol. Cell Biol.9, 355–366 (2008). Article Google Scholar
Thery, M. et al. The extracellular matrix guides the orientation of the cell division axis. Nat. Cell Biol.7, 947–953 (2005). ArticleCAS Google Scholar
Toyoshima, F. & Nishida, E. Integrin-mediated adhesion orients the spindle parallel to the substratum in an EB1- and myosin X-dependent manner. EMBO J.26, 1487–1498 (2007). ArticleCAS Google Scholar
Siller, K. H. & Doe, C. Q. Spindle orientation during asymmetric cell division. Nat. Cell Biol.11, 365–374 (2009). ArticleCAS Google Scholar
Kardon, J. R. & Vale, R. D. Regulators of the cytoplasmic dynein motor. Nat. Rev. Mol. Cell Biol.10, 854–865 (2009). ArticleCAS Google Scholar
Woodard, G. E. et al. Ric-8A and Gi α recruit LGN, NuMA, and dynein to the cell cortex to help orient the mitotic spindle. Mol. Cell Biol.30, 3519–3530 (2010). ArticleCAS Google Scholar
Du, Q. & Macara, I. G. Mammalian Pins is a conformational switch that links NuMA to heterotrimeric G proteins. Cell119, 503–516 (2004). ArticleCAS Google Scholar
Sumara, I. et al. Roles of polo-like kinase 1 in the assembly of functional mitotic spindles. Curr. Biol.14, 1712–1722 (2004). ArticleCAS Google Scholar
Bayliss, R., Sardon, T., Vernos, I. & Conti, E. Structural basis of Aurora-A activation by TPX2 at the mitotic spindle. Mol. Cell12, 851–862 (2003). ArticleCAS Google Scholar
Lampson, M. A. & Cheeseman, I. M. Sensing centromere tension: Aurora B and the regulation of kinetochore function. Trends Cell Biol.21, 133–140 (2011). ArticleCAS Google Scholar
Kalab, P., Weis, K. & Heald, R. Visualization of a Ran–GTP gradient in interphase and mitotic Xenopus egg extracts. Science295, 2452–2456 (2002). ArticleCAS Google Scholar
Kalab, P. & Heald, R. The RanGTP gradient—a GPS for the mitotic spindle. J. Cell Sci.121, 1577–1586 (2008). ArticleCAS Google Scholar
Kornbluth, S., Dasso, M. & Newport, J. Evidence for a dual role for TC4 protein in regulating nuclear structure and cell cycle progression. J. Cell Biol.125, 705–719 (1994). ArticleCAS Google Scholar
Nishitani, H. et al. Loss of RCC1, a nuclear DNA-binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis. EMBO J.10, 1555–1564 (1991). ArticleCAS Google Scholar
Wiese, C. et al. Role of importin- β in coupling Ran to downstream targets in microtubule assembly. Science291, 653–656 (2001). ArticleCAS Google Scholar
Nachury, M. V. et al. Importin β is a mitotic target of the small GTPase Ran in spindle assembly. Cell104, 95–106 (2001). ArticleCAS Google Scholar
Wee, B., Johnston, C. A., Prehoda, K. E. & Doe, C. Q. Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientation. J. Cell Biol.195, 369–376 (2011). ArticleCAS Google Scholar
Fink, J. et al. External forces control mitotic spindle positioning. Nat. Cell Biol.13, 771–778 (2011). ArticleCAS Google Scholar
Knoblich, J. A. Asymmetric cell division: recent developments and their implications for tumour biology. Nat. Rev. Mol. Cell Biol.11, 849–860 (2010). ArticleCAS Google Scholar
Kline, S. L., Cheeseman, I. M., Hori, T., Fukagawa, T. & Desai, A. The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. J. Cell Biol.173, 9–17 (2006). ArticleCAS Google Scholar
Cheeseman, I. M. et al. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev.18, 2255–2268 (2004). ArticleCAS Google Scholar
Schmidt, J. C. et al. Aurora B kinase controls the targeting of the Astrin-SKAP complex to bioriented kinetochores. J. Cell Biol.191, 269–280 (2010). ArticleCAS Google Scholar
Hutchins, J. R. et al. Systematic analysis of human protein complexes identifies chromosome segregation proteins. Science328, 593–599 (2010). ArticleCAS Google Scholar
Cheeseman, I. M. & Desai, A. A combined approach for the localization and tandem affinity purification of protein complexes from metazoans. Sci. STKE2005, pl1 (2005). PubMed Google Scholar
Washburn, M. P., Wolters, D. & Yates, J. R. 3rd Large-scale analysis of the yeast proteome by multidimensional protein identification technology. Nat. Biotechnol.19, 242–247 (2001). ArticleCAS Google Scholar
Weis, K., Dingwall, C. & Lamond, A. I. Characterization of the nuclear protein import mechanism using Ran mutants with altered nucleotide binding specificities. EMBO J.15, 7120–7128 (1996). ArticleCAS Google Scholar