SMIF, a Smad4-interacting protein that functions as a co-activator in TGFβ signalling (original) (raw)

• Attisano, L. & Wrana, J. L. Smads as transcriptional co-modulators. Curr. Opin. Cell Biol. 12, 235–243 (2000).
  Article CAS PubMed Google Scholar
• Massague, J., Blain, S. W. & Lo, R. S. TGFβ signalling in growth control, cancer, and heritable disorders. Cell 103, 295–309 (2000).
  Article CAS PubMed Google Scholar
• Heldin, C. H., Miyazono, K. & ten Dijke, P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465–471 (1997).
  Article CAS PubMed Google Scholar
• Massague, J. & Wotton, D. Transcriptional control by the TGF-β/Smad signalling system. EMBO J. 19, 1745–1754 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• Massague, J. & Chen, Y. G. Controlling TGF-β signalling. Genes Dev. 14, 627–644 (2000).
  CAS PubMed Google Scholar
• Wrana, J. L. & Attisano, L. The Smad pathway. Cytokine Growth Factor Rev. 11, 5–13 (2000).
  Article CAS PubMed Google Scholar
• Chen, X., Rubock, M. J. & Whitman, M. A transcriptional partner for MAD proteins in TGF-β signalling. Nature 383, 691–696. (1996).
  Article CAS PubMed Google Scholar
• Verschueren, K. et al. SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5′ -CACCT sequences in candidate target genes. J. Biol. Chem. 274, 20489–20498 (1999).
  Article CAS PubMed Google Scholar
• Wotton, D., Lo, R. S., Lee, S. & Massague, J. A Smad transcriptional corepressor. Cell 97, 29–39 (1999).
  Article CAS PubMed Google Scholar
• Shioda, T. et al. Transcriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivator. Proc. Natl Acad. Sci. USA 95, 9785–9790 (1998).
  Article CAS PubMed PubMed Central Google Scholar
• Hata, A. et al. OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signalling pathways. Cell 100, 229–240 (2000).
  Article CAS PubMed Google Scholar
• Feng, X. H., Zhang, Y., Wu, R. Y. & Derynck, R. The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are co-activators for smad3 in TGF-β-induced transcriptional activation. Genes Dev. 12, 2153–2163 (1998).
  Article CAS PubMed PubMed Central Google Scholar
• Shimizu, K., Bourillot, P.-Y., Nielsen, S. J., Zorn, A. M. & Gurdon, J. B. Swift is a novel BRCT domain co-activator of Smad2 in Transforming Growth Factor β signalling. Mol. Cell Biol. 21, 3901–3912 (2001).
  Article CAS PubMed PubMed Central Google Scholar
• Pouponnot, C., Jayaraman, L. & Massague, J. Physical and functional interaction of SMADs and p300/CBP. J. Biol. Chem. 273, 22865–22868 (1998).
  Article CAS PubMed Google Scholar
• Itoh, S., Ericsson, J., Nishikawa, J., Heldin, C. H. & ten Dijke, P. The transcriptional co-activator P/CAF potentiates TGF-β/Smad signalling. Nucleic Acids Res. 28: 4291–4298 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• Stroschein, S. L., Wang, W., Zhou, S., Zhou, Q. & Luo, K. Negative feedback regulation of TGF-β signalling by the SnoN oncoprotein. Science 286, 771–774 (1999).
  Article CAS PubMed Google Scholar
• Luo, K. et al. The Ski oncoprotein interacts with the Smad proteins to repress TGFβ signalling. Genes Dev. 13, 2196–2206 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Lange, D. et al. Expression of TGF-b related Smad proteins in human epithelial skin tumors. Int. J. Oncol. 14, 1049–1056 (1999).
  CAS PubMed Google Scholar
• Liu, F., Pouponnot, C. & Massague, J. Dual role of the Smad4/DPC4 tumor suppressor in TGFβ-inducible transcriptional complexes. Genes Dev. 11, 3157–3167 (1997).
  Article CAS PubMed PubMed Central Google Scholar
• Zhou, S. et al. Targeted deletion of Smad4 shows it is required for transforming growth factor β and activin signalling in colorectal cancer cells. Proc. Natl Acad. Sci. USA 95, 2412–2416 (1998).
  Article CAS PubMed PubMed Central Google Scholar
• Adams, M. D. et al. The genome sequence of Drosophila melanogaster. Science 287, 2185–2195 (2000).
  Article PubMed Google Scholar
• Kozak, M. The scanning model for translation: an update. J. Cell. Biol. 108, 229–241 (1989).
  Article CAS PubMed Google Scholar
• de Caestecker, M. P. et al. The Smad4 activation domain (SAD) is a proline-rich, p300-dependent transcriptional activation domain. J. Biol. Chem. 275, 2115–2122 (2000).
  Article CAS PubMed Google Scholar
• Goldman, P. S., Tran, V. K. & Goodman, R. H. The multifunctional role of the co-activator CBP in transcriptional regulation. Recent Prog. Horm. Res. 52, 103–119 (1997).
  CAS PubMed Google Scholar
• Shikama, N., Lyon, J. & La Thangue, N. B. The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol. 7, 230–236 (1997).
  Article CAS Google Scholar
• Liu, F. et al. A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620–623 (1996).
  Article CAS PubMed Google Scholar
• Labbe, E., Silvestri, C., Hoodless, P. A., Wrana, J. L. & Attisano, L. Smad2 and Smad3 positively and negatively regulate TGF b-dependent transcription through the forkhead DNA-binding protein FAST2. Mol. Cell 2, 109–120 (1998).
  Article CAS PubMed Google Scholar
• Pertovaara, L. et al. Enhanced jun gene expression is an early genomic response to transforming growth factor β stimulation. Mol. Cell Biol. 9, 1255–1262 (1989).
  Article CAS PubMed PubMed Central Google Scholar
• Jonk, L. J., Itoh, S., Heldin, C. H., ten Dijke, P. & Kruijer, W. Identification and functional characterization of a Smad binding element (SBE) in the JunB promoter that acts as a transforming growth factor-β, activin, and bone morphogenetic protein-inducible enhancer. J. Biol. Chem. 273, 21145–21152 (1998).
  Article CAS PubMed Google Scholar
• Marazzi, G., Wang, Y. & Sassoon, D. Msx2 is a transcriptional regulator in the BMP4-mediated programmed cell death pathway. Dev. Biol. 186, 127–138 (1997).
  Article CAS PubMed Google Scholar
• Phippard, D. J. et al. Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development. Development 122, 2729–2737 (1996).
  CAS PubMed Google Scholar
• Nasevicius, A. & Ekker, S. C. Effective targeted gene 'knockdown' in zebrafish. Nature Genet. 26, 216–220 (2000).
  Article CAS PubMed Google Scholar
• Lele, Z., Bakkers, J. & Hammerschmidt, M. Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations. Genesis 30, 190–194 (2001).
  Article CAS PubMed Google Scholar
• Solnica-Krezel, L. Pattern formation in zebrafish – fruitful liaisons between embryology and genetics. Curr. Top. Dev. Biol. 41, 1–35 (1999).
  CAS PubMed Google Scholar
• Schier, A. F. & Shen, M. M. Nodal signalling in vertebrate development. Nature 403, 385–389 (2000).
  Article CAS PubMed Google Scholar
• Davidson, A. J. & Zon, L. I. Turning mesoderm into blood: the formation of hematopoietic stem cells during embryogenesis. Curr. Top. Dev. Biol. 50, 45–60 (2000).
  Article CAS PubMed Google Scholar
• de Caestecker, M. P. et al. Characterization of functional domains within Smad4/DPC4. J. Biol. Chem. 272, 13690–13696 (1997).
  Article CAS PubMed Google Scholar
• Shen, X. et al. TGF-b-induced phosphorylation of Smad3 regulates its interaction with co-activator p300/CREB-binding protein. Mol. Biol. Cell 9, 3309–3319 (1998).
  Article CAS PubMed PubMed Central Google Scholar
• Nishihara, A. et al. Role of p300, a transcriptional co-activator, in signalling of TGF-β. Genes Cells 3, 613–623 (1998).
  Article CAS PubMed Google Scholar
• Yahata, T. et al. The MSG1 non-DNA-binding transactivator binds to the p300/CBP co-activators, enhancing their functional link to the Smad transcription factors. J. Biol. Chem. 275, 8825–8834 (2000).
  Article CAS PubMed Google Scholar
• Shioda, T., Fenner, M. H. & Isselbacher, K. J. Msg1, a novel melanocyte-specific gene, encodes a nuclear protein and is associated with pigmentation. Proc. Natl Acad. Sci. USA 93, 12298–12303 (1996).
  Article CAS PubMed PubMed Central Google Scholar
• Dunwoodie, S. L., Rodriguez, T. A. & Beddington, R. S. Msg1 and Mrg1, founding members of a gene family, show distinct patterns of gene expression during mouse embryogenesis. Mech. Dev. 72, 27–40 (1998).
  Article CAS PubMed Google Scholar
• Bai, R. Y. et al. The SH2-containing adapter protein GRB10 interacts with BCR-ABL. Oncogene 17, 941–948 (1998).
  Article CAS PubMed Google Scholar
• Boyd, F. T. & Massague, J. Transforming growth factor-b inhibition of epithelial cell proliferation linked to the expression of a 53-kDa membrane receptor. J. Biol. Chem. 264, 2272–2278 (1989).
  CAS PubMed Google Scholar
• Laiho, M., Weis, M. B. & Massague, J. Concomitant loss of transforming growth factor (TGF)-β receptor types I and II in TGF-β-resistant cell mutants implicates both receptor types in signal transduction. J. Biol. Chem. 265, 18518–18524 (1990).
  CAS PubMed Google Scholar
• Goyette, M. C. et al. Progression of colorectal cancer is associated with multiple tumor suppressor gene defects but inhibition of tumorigenicity is accomplished by correction of any single defect via chromosome transfer. Mol. Cell. Biol. 12, 1387–1395 (1992).
  Article CAS PubMed PubMed Central Google Scholar
• Bai, R. Y., Dieter, P., Peschel, C., Morris, S. W. & Duyster, J. Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-γ to mediate its mitogenicity. Mol. Cell. Biol. 18, 6951–6961 (1998).
  Article CAS PubMed PubMed Central Google Scholar
• Hoodless, P. A. et al. MADR1, a MAD-related protein that functions in BMP2 signalling pathways. Cell 85, 489–500 (1996).
  Article CAS PubMed Google Scholar
• Hammerschmidt, M. et al. Dino and mercedes, two genes regulating dorsal development in the zebrafish embryo. Development 123, 95–102 (1996).
  CAS PubMed Google Scholar
• Molitor, J. A., Walker, W. H., Doerre, S., Ballard, D. W. & Greene, W. C. NF-kappa B: a family of inducible and differentially expressed enhancer- binding proteins in human T cells. Proc. Natl Acad. Sci. USA 87, 10028–10032 (1990).
  Article CAS PubMed PubMed Central Google Scholar