Inhibition of Minicircular DNA Replication in Escherichia coli 15 by Rifampicin (original) (raw)
- Letters to Editor
- Published: 16 August 1972
Nature New Biology volume 238, pages 202–203 (1972)Cite this article
Abstract
RECENT evidence supports a direct involvement of transcription in the DNA replication of _E. coli_1,2, phage λ3, and phage M 134,5. Transcription of the replication origin appears to be essential for the initiation of a new round of DNA replication. However, all the systems mentioned have particular disadvantages; for example, DNA replication in these systems also requires protein synthesis, and since a transcriptional block also inhibits protein synthesis, setting up experiments and interpretation of data can be difficult.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
We are sorry, but there is no personal subscription option available for your country.
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Additional access options:
References
- Messer, W., Molec. Gen. Gen. (in the press).
- Lark, K. G., J. Mol. Biol., 64, 47 (1972).
Article CAS Google Scholar - Dove, W. F., Hargrove, E., Ohashi, M., Haugli, F., and Guha, A., Jap. J. Genet., 44, Suppl. 1, 11 (1969).
Article Google Scholar - Brutlag, D., Schekman, R., and Kornberg, A., Proc. US Nat. Acad. Sci., 68, 2826 (1971).
Article CAS Google Scholar - Staudenbauer, W. L., and Hofschneider, P. H., Proc. US Nat. Acad. Sci., 69, 1634 (1972).
Article CAS Google Scholar - Cozzarelli, N. R., Kelly, R. G., and Kornberg, A., Proc. US Nat. Acad. Sci., 60, 392 (1968).
Article Google Scholar - Lee, C. S., and Davidson, N., Biochem. Biophys. Res. Commun., 32, 757 (1968).
Article CAS Google Scholar - Clayton, B., and Vinograd, J., Nature, 216, 652 (1967).
Article CAS Google Scholar - Sethi, V. S., Progr. Biophys. Mol. Biol., 23, 67 (1971).
Article CAS Google Scholar - Adams, M. H., Bacteriophages (Interscience Publishers, New York, 1959).
- Ray, D. S., and Schekman, R. W., Biochim. Biophys. Acta, 179, 398 (1969).
Article CAS Google Scholar - Wirtz, A., and Hofschneider, P. H., Eur. J. Biochem., 17, 141 (1970).
Article CAS Google Scholar - Staudenbauer, W. L., and Hofschneider, P. H., Biochem. Biophys. Res. Commun., 42, 1035 (1971).
Article CAS Google Scholar
Author information
Authors and Affiliations
- Max-Planck-Institut für Biochemie, 8033, Martinsried bei, München
J. MESSING, W. L. STAUDENBAUER & P. H. HOFSCHNEIDER
Authors
- J. MESSING
You can also search for this author inPubMed Google Scholar - W. L. STAUDENBAUER
You can also search for this author inPubMed Google Scholar - P. H. HOFSCHNEIDER
You can also search for this author inPubMed Google Scholar
Rights and permissions
About this article
Cite this article
MESSING, J., STAUDENBAUER, W. & HOFSCHNEIDER, P. Inhibition of Minicircular DNA Replication in Escherichia coli 15 by Rifampicin.Nature New Biology 238, 202–203 (1972). https://doi.org/10.1038/newbio238202a0
- Received: 15 February 1972
- Revised: 28 April 1972
- Issue Date: 16 August 1972
- DOI: https://doi.org/10.1038/newbio238202a0