Multiple ADH genes are associated with upper aerodigestive cancers (original) (raw)

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Acknowledgements

First and foremost we thank all participants of the CE, LA and ARCAGE studies and the staff in the collaborating centers. Subject recruitment was supported by four grants from the European Commission (IC15-CT96-0313, IC15-CT98-0322, IC18-CT97-0222 and QLK1-CT2001-00182) and one grant from the World Cancer Research Fund (WCRF 99A28). Genotyping and analysis was funded by a National Cancer Institute R01 grant (contract no. CA 092039-01A2). The funding agencies did not have any involvement in the study design, collection, analysis and interpretation of the data or in the writing of report and decision to submit the paper.

Author information

Authors and Affiliations

  1. International Agency for Research on Cancer, Lyon, France
    Mia Hashibe, James D McKay, Maria Paula Curado, Amelie Chabrier, Rayjean J Hung, Valerie Gaborieau, Paolo Boffetta & Paul Brennan
  2. Hospital Araujo Jorge, Goiania, and Populational Cancer Register of Goiania, Brazil
    Maria Paula Curado & Jose Carlos Oliveira
  3. Escola Nacional de Suade Publica, Rio de Janeiro, Brazil
    Sergio Koifman & Rosalina Koifman
  4. Cancer Research Centre, Moscow, Russia
    David Zaridze & Oxana Shangina
  5. Universidade de Sao Paulo, Sao Paulo, Brazil
    Victor Wünsch-Filho, Jose Eluf-Neto & Jose Eduardo Levi
  6. Institute of Oncology Angel H. Roffo, University of Buenos Aires, Argentina
    Elena Matos
  7. University of Athens School of Medicine, Athens, Greece
    Pagona Lagiou & Areti Lagiou
  8. Institut National de la Santé et de la Recherche Médicale U794, Evry, France
    Simone Benhamou
  9. Geneva Cancer Registry, Geneva, Switzerland
    Christine Bouchardy
  10. Institute of Occupational Medicine, Lodz, Poland
    Neonilia Szeszenia-Dabrowska
  11. Universidade Federal de Pelotas, Pelotas, Brazil
    Ana Menezes & Marinel Mór Dall'Agnol
  12. Unit of Cancer Epidemiology, CeRMS and University of Turin, Turin, Italy
    Franco Merletti & Lorenzo Richiardi
  13. Institute of Oncology and Radiobiology, Havana, Cuba
    Leticia Fernandez & Juan Lence
  14. Aviano Cancer Centre, Aviano, Italy
    Renato Talamini
  15. General Hospital of Pordenone, Pordenone, Italy
    Luigi Barzan
  16. Institute of Public Health, Bucharest, Romania
    Dana Mates
  17. University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania
    Ioan Nicolae Mates
  18. Cancer Registry of Norway, Oslo, Norway
    Kristina Kjaerheim
  19. University of Aberdeen School of Medicine, Aberdeen, UK
    Gary J Macfarlane & Tatiana V Macfarlane
  20. University of Padua, Padova, Italy
    Lorenzo Simonato & Cristina Canova
  21. Institute of Hygiene and Epidemiology, Prague, Czech Republic
    Ivana Holcátová & Vladimir Bencko
  22. Institut Català d'Oncologia, Barcelona, Spain
    Antonio Agudo & Xavier Castellsagué
  23. University of Newcastle Dental School, Newcastle, UK
    Ray Lowry
  24. Palacky University, Olomouc, Czech Republic
    Vladimir Janout & Helena Kollarova
  25. University of Glasgow Dental School, Glasgow, Scotland
    David I Conway
  26. University of Leeds Centre for Epidemiology and Biostatistics, Leeds, UK
    Patricia A McKinney
  27. Information Services Division, NHS National Services Scotland, Edinburgh, Scotland
    Patricia A McKinney
  28. Croatian National Cancer Registry, Zagreb, Croatia
    Ariana Znaor
  29. Specialized State Health Institute, Banská Bystrica, Slovakia
    Eleonora Fabianova
  30. The Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
    Jolanta Lissowska
  31. School of Public Health, University of California at Berkeley, Berkeley, 94720, California, USA
    Rayjean J Hung

Authors

  1. Mia Hashibe
  2. James D McKay
  3. Maria Paula Curado
  4. Jose Carlos Oliveira
  5. Sergio Koifman
  6. Rosalina Koifman
  7. David Zaridze
  8. Oxana Shangina
  9. Victor Wünsch-Filho
  10. Jose Eluf-Neto
  11. Jose Eduardo Levi
  12. Elena Matos
  13. Pagona Lagiou
  14. Areti Lagiou
  15. Simone Benhamou
  16. Christine Bouchardy
  17. Neonilia Szeszenia-Dabrowska
  18. Ana Menezes
  19. Marinel Mór Dall'Agnol
  20. Franco Merletti
  21. Lorenzo Richiardi
  22. Leticia Fernandez
  23. Juan Lence
  24. Renato Talamini
  25. Luigi Barzan
  26. Dana Mates
  27. Ioan Nicolae Mates
  28. Kristina Kjaerheim
  29. Gary J Macfarlane
  30. Tatiana V Macfarlane
  31. Lorenzo Simonato
  32. Cristina Canova
  33. Ivana Holcátová
  34. Antonio Agudo
  35. Xavier Castellsagué
  36. Ray Lowry
  37. Vladimir Janout
  38. Helena Kollarova
  39. David I Conway
  40. Patricia A McKinney
  41. Ariana Znaor
  42. Eleonora Fabianova
  43. Vladimir Bencko
  44. Jolanta Lissowska
  45. Amelie Chabrier
  46. Rayjean J Hung
  47. Valerie Gaborieau
  48. Paolo Boffetta
  49. Paul Brennan

Contributions

P. Boffetta, P. Brennan, M.P.C., J.C.O., S.K., R.K., V.W.-F., J.E.N., E.M., A.M., M.M.D., L.F. and J. Lence jointly designed the LA study and organized the recruitment of participants. P. Brennan, P. Boffetta, D.Z., O.S., N.S.-D., D.M., I.N.M., I.H., V.J., H.K., E.F. and J. Lissowska jointly designed the CE study and organized the recruitment of participants. P. Brennan, M.H., P.L., A.L., S.B., C.B., F.M., L.R., R.T., L.B., K.K., G.J.M., T.V.M., L.S., C.C., A.A., X.C., R.L., D.I.C., P.A.M., A.Z. and V.B. jointly designed the ARCAGE study and organized the recruitment of participants. J.D.M., M.H., A.C., R.J.H., V.G., J.E.L. and P. Brennan organized biological sample storage. J.D.M., M.H., V.G. and P. Brennan conducted SNP selection and the statistical analysis. M.H., J.D.M. and P. Brennan drafted the manuscript, and all coauthors contributed to the final draft.

Corresponding author

Correspondence toPaul Brennan.

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Hashibe, M., McKay, J., Curado, M. et al. Multiple ADH genes are associated with upper aerodigestive cancers.Nat Genet 40, 707–709 (2008). https://doi.org/10.1038/ng.151

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