Next-generation association studies for complex traits (original) (raw)

Nature Genetics volume 43, pages 287–288 (2011)Cite this article

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A new study successfully applies complementary whole-genome sequencing and imputation approaches to establish robust disease associations in an isolated population. This strategy is poised to help elucidate the role of variants at the low end of the allele frequency spectrum in the genetic architecture of complex traits.

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  1. Eleftheria Zeggini is at the Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.,
    Eleftheria Zeggini

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  1. Eleftheria Zeggini
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Correspondence toEleftheria Zeggini.

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The author declares no competing financial interests.

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Zeggini, E. Next-generation association studies for complex traits.Nat Genet 43, 287–288 (2011). https://doi.org/10.1038/ng0411-287

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