Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development (original) (raw)
References
Hill, R.E. et al. A new family of mouse homeo box-containing genes: molecular structure chromosomal location & developmental expression of Hox-7.1. Genes Dev.3, 26–37 (1989). ArticleCASPubMed Google Scholar
Robert, B., Sassoon, D., Jacq, B., Gehring, W. & Buckingham, M. >Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis. EMBO J.8, 91–100 (1989). ArticleCASPubMedPubMed Central Google Scholar
Gehring, W.J. The homeobox: Structural and evolutionary aspects, in Molecular Approaches toDevelopmental Biology (eds Firtel, R.A. & Davidson, E.H.) 115–129 (Liss, New York, 1987). Google Scholar
Holland, P.W.H. Cloning and evolutionary analysis of msh like homeobox genes from mouse, zebrafish and ascidian. Gene98, 253–257 (1991). ArticleCASPubMed Google Scholar
Monaghan, A.P. et al. The _Msh_-like homeobox genes define domains in the developing vertebrate eye. Development112,1053–1061 (1991). CASPubMed Google Scholar
Bell, J.R. et al. Genomic structure, chromosomal location, and evolution of the mouse Hox-8 gene. Genomics16, 123–131 and 17, 800 (1993). ArticleCASPubMed Google Scholar
Ivens, A. et al. The human homeobox gene Hox7 maps chromosome 4p16.1 and may be implicated in Wolf-Hirschhorn syndrome. Human Genet.84, 473–476 (1990). ArticleCAS Google Scholar
Hewitt, J.E., Clark, L.N., Ivens, A. & Williamson, R. Structure and sequence of the human homeobox gene Hox7. Genomics11, 670–678 (1991). ArticleCASPubMed Google Scholar
Jabs, E.W. et al. A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis. Cell75, 443–450 (1993). ArticleCASPubMed Google Scholar
MacKenzie, A., Leeming, G.L., Jowett, A.K., Ferguson, M.W.J. & Sharpe, P.T. The homeobox gene Hox7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. Development111, 269–285 (1991). CASPubMed Google Scholar
MacKenzie, A., Ferguson, M.W.J. & Sharpe, P.T. Hox-7 expression during murine craniofacial development. Development113, 601–611 (1991). CASPubMed Google Scholar
MacKenzie, A., Ferguson, M.W.J. & Sharpe, P.T. Expression patterns of the homeobox gene Hox 8 in the mouse embryo suggest a role in specifying tooth initiation and shape. Development115, 403–420 (1992). CASPubMed Google Scholar
Suzuki, H.R., Padanilam, B.J., Vitale, E., Ramirez, F. & Solursh, M. Repeating developmental expression of G-Hox7, a novel homeobox-containing gene in the chicken. Dev. Biol.148, 375–388 (1991). ArticleCASPubMed Google Scholar
Lyons, G.E., Houzelstein, D., Sassoon, D., Robert, B. & Buckingham, M. Multiple sites of Hox-7 expression during mouse embryogenesis: comparison with retinoic acid receptor mRNA localization. Molec. repro. Dev.32, 303–314(1992). ArticleCAS Google Scholar
Chan-Thomas, P.S., Thompson, R.P., Robert, B., Yacoub, M.H. & Barton, P.J.R. Expression of homeobox genes Msx-1 (Hox-7) and Msx-2 (Hox-8) during cardiac development in chick. Develop. Dyn.197, 203–216 (1993). ArticleCAS Google Scholar
Robert, B., Lyons, G., Simandl, B.K., Kuroiwa, A. & Buckingham, M. The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes Dev.5, 2363–2374 (1991). ArticleCASPubMed Google Scholar
Davidson, D.R., Crawley, A., Hill, R.E. & Tickle, C. Position dependent expression of two related homeobox genes in developing vertebrate limbs. Nature352, 429–431 (1991). ArticleCASPubMed Google Scholar
Coelho, C.N.D., Krabbenhoft, K.M., Upholt, W.B., Fallon, J.F. & Kosher, R.A. Altered expression of the chicken homeobox-containing gene GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos. Development113, 1487–1493 (1991). CASPubMed Google Scholar
Coelho, C.N.D., Upholt, W.B. & Kosher, R.A. Role of the chicken homeobox-containing genes GHox-4.6 and GHox-8 in the specification of positional identities during the development of normal and polydactylous chick limb buds. Development115, 629–637 (1992). CASPubMed Google Scholar
Ros, M.A. et al. Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds. Development116, 811–818 (1992). CASPubMed Google Scholar
Brown, J.M. et al. Experimental analysis of the control of expression of the homeobox-gene Msx-1 in the developing limb and face. Development119, 41–48 (1993). CASPubMed Google Scholar
Takahashi, Y., Bontoux, M. & Le Douarin, N.M. Epithelio-mesenchymal interactions are critical for Quox 7 expression and membrane bone differentiation in the neural crest derived mandibular mesenchyme. EMBOJ.10, 2387–2393(1991). ArticleCAS Google Scholar
Jowett, A.K., Vainio, S., Ferguson, M.W.J., Sharpe, P.T. & Thesleff, I. Epithelial-mesenchymal interactions are required for msx1 and msx2 gene expression in the developing murine molar tooth. Development117, 461–470(1993). CASPubMed Google Scholar
Takahashi, Y., Monsoro-Burg, A.-H., Bontoux, M. & Le Douarin, N.M. A role for Quox-8 in the establishment of the dorsoventral pattern during vertebrate development. Proc. natn. Acad. Sci. U.S.A.89, 10237–10241 (1992). ArticleCAS Google Scholar
Davidson, D.R. & Hill, R.E. Msh-like genes: a family of homeobox genes with wide ranging expression during vertebrate development. Sem. Dev. Biol.2, 405–412 (1991). Google Scholar
Muneoka, K. & Sasoon, D. Molecular aspects of regeneration in developing vertebrate limbs. Dev. Biol.152, 37–49 (1992). ArticleCASPubMed Google Scholar
Izpisúa-Belmonte, J.-C. & Duboule, D. Homeobox genes and pattern formation in the vertebrate limb. Dev. Biol.152, 26–36 (1992). ArticlePubMed Google Scholar
Davidson, E.H. Later embryogenesis: regulatory circuitry in morphogenetic fields. Development118, 665–690 (1993). CASPubMed Google Scholar
Robert, B. et al. Induction phenomena in vertebrate limb formation and expression of homeobox genes. Ann. Génétique36, 39–45 (1993). CAS Google Scholar
Gorlin, R.J., Cohen, M.M.Jr., & Levin, L.S. Syndromes of the Head and Neck. Oxford Monograph on Medical genetics No. 19, Third edition. 693–714 (Oxford University Press, Oxford, England, 1990). Google Scholar
Ranta, R. A review of tooth formation in children with cleft lip/palate. A. J. Orthod. Dentofac. Orthop.90, 11–18 (1986). ArticleCAS Google Scholar
Randall, P., Krogman, W.M. & Jahina, S., Robin and the syndrome that bears his name. Cleft Palate J.2, 237–246 (1965). Google Scholar
McKusick, V.A. Mendelian Inheritance in Man. 8th edn 1138–1139 (Johns Hopkins University Press, Baltimore 1988). Google Scholar
Couly, G. and Le Douarin, N.M. The fate map of the cephalic neural primordium at the presomitic to the 3-somite stage in the avian embryo. Development Supp.103, 101–113 (1988). Google Scholar
Couly, G.F., Coltey, P.M. & Le Douarin, N.M. The triple origin of skull in higher vertebrates: a study in quail-chick chimeras. Development117, 409–429 (1993). CASPubMed Google Scholar
Noden, D.M. Interactions and fates of avian craniofacial mesenchyme. Development Supp.103, 121–140 (1988). Google Scholar
Lumsden, A.G.S. Spatial organization of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ. Development Supp.103, 155–169 (1988). Google Scholar
Johnston, M.C. The neural crest in abnormalities of the face and brain. Birth Defects: Original Article Series, Vol. Xl(7), 1 18 (The National March of Dimes Foundation, 1975). Google Scholar
Sulik, K.K., Cook, C.S. & Webster, W.S. Teratogenesis and craniofacial malformations: relationships to cell death. Development Supp.103, 213–232 (1988). CAS Google Scholar
Palmer, R.M. & Lumsden, A.G.S. Development of periodontal ligament and alveolar bone in homografted recombinations of enamel organs and papillary, pulpal and follicular mesenchyme in the mouse. Arch. Oral Biol.32, 281–289 (1987). ArticleCASPubMed Google Scholar
Vainio, S., Karavanova, I., Jowett, A. & Thesleff, I. Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell75, 45–58 (1993). ArticleCASPubMed Google Scholar
Coelho, C.N.D. et al. Expression of the chicken homeobox-containing gene GHox-8 during embryonic chick limb development. Mech. Dev.34, 143–154 (1991). ArticleCASPubMed Google Scholar
Coelho, C.N.D., Sumoy, L., Kosher, R.A. & Upholt, W.B., GHox-7: A chicken homeobox-containing gene expressed in a fashion consistent with a role in patterning events during embryonic chick limb development. Differentiation49, 85–92 (1992). ArticleCASPubMed Google Scholar
Ferguson, M. Palate development. Development Supp.103, 41–60 (1988). Google Scholar
Fitch, N. Development of cleft palate in mice homozygous for the shorthead mutation. J. Morphot.109, 151–157 (1961). ArticleCAS Google Scholar
Seegmiller, R.E. & Fraser, F.C. Mandibular growth retardation as a cause of cleft palate in mice homozygous for the chondrodysplasia gene. J. Embryol. exp. Morph.38, 227–238 (1977). CASPubMed Google Scholar
Juriloff, D.M. & Harris, M.J. Abnormal facial development in the mouse mutant first arch. J. Cranio. Gen. devl. Biol.3, 317–337 (1983). CAS Google Scholar
Culiat, C.T. et al. Concordance between isolated cleft palate in mice and alterations within a region including the gene encoding the β3 subunit of the type Aγ-aminobutyric acid receptor. Proc. natn. Acad. Sci. U.S.A.90, 5105–5109(1993).
Nakatsu, Y. et al. A cluster of three GABA receptor subunit genes is deleted in a neurological mutant of the mouse p locus. Nature364, 448–450 (1993). ArticleCASPubMed Google Scholar
Gendron-Maguire, M. et al. Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crest. Cell75, 1317–1331 (1993). ArticleCASPubMed Google Scholar
Rijli, F.M. et al. A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2, which acts as a homeotic selector gene. Cell75, 1333–1349 (1993). ArticleCASPubMed Google Scholar
Farrall, M. & Holder, S. Familal recurrence-pattern analysis of cleft lip with or without cleft palate. Am. J. hum. Gen.50, 270–277 (1992). CAS Google Scholar
Marazita, M.L., Hu, D-N, Spence, M.A., Liu, Y-E., Melnick, M. Cleft lip with or without cleft palate in Shanghai, China: evidence for an autosomal major locus. Am. J. hum. Gen.51, 648–653 (1992). CAS Google Scholar
Kurnit, D.M., Layton, W.M. & Matthysse, S., Genetics, chance, and morphogenesis. Am. J. hum. Gen.41, 979–995 (1987). CAS Google Scholar
Li, E., Bestor, T. & Jaenisch, R. argeted mutation of the DNA methyl transferase gene results in embryonic lethality. Cell69, 915–926 (1992). ArticleCASPubMed Google Scholar
Zijlstra, M., Li, E., Sajjadi, F., Subramani, S. & Jaensich, R. Germ line transmission of adisrupted β2-microglobulin gene produced by homologous recombination in embryonic stem cells. Nature342, 435–438 (1989). ArticleCASPubMed Google Scholar
Robertson, E.J. Embryo-derived stem cell lines in Teratocarcinomas and embryonic stem cells a practical approach (ed. Roberston. E.J.)71–112(IRL press, Oxford, 1987). Google Scholar
Thomas, K. & Capecchi, M. Site directed mutagenesis by gene targeting in mouse embryo derived stem cells. Cell51, 503–512 (1987). ArticleCASPubMed Google Scholar
Bradley, A. Production and analysis of chimaeric mice. in Teratocarcinomas and embryonic stem cells, a practical approach (ed. Robertson, E.J.) 113–151 (IRL Press, Oxford, 1987). Google Scholar
Laird, P.W. et al. Simplified mammalian DNA isolation procedure. Nuc. Acid Res.19, 4293 (1991). ArticleCAS Google Scholar
McLeod, M.J. Differential staining of cartilage and bone in whole mouse fetuses by alcian blue and alizarin red S. Teratology22, 299–301 (1980). ArticleCASPubMed Google Scholar