Molecular portraits and the family tree of cancer (original) (raw)
Perou, C.M. et al. Molecular portraits of human breast tumours. Nature406, 747–752 (2000). ArticleCAS Google Scholar
Sørlie, T. et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl Acad. Sci. USA98, 10869–10874 (2001). Article Google Scholar
van 't Veer, L.J. et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature415, 530–536 (2002). ArticleCAS Google Scholar
West, M. et al. Predicting the clinical status of human breast cancer by using gene expression profiles. Proc. Natl Acad. Sci. USA98, 11462–11467 (2001). ArticleCAS Google Scholar
Hedenfalk, I. et al. Gene-expression profiles in hereditary breast cancer. N. Engl. J. Med.344, 539–548 (2001). ArticleCAS Google Scholar
Gruvberger, S. et al. Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns. Cancer Res.61, 5979–5984 (2001). CAS Google Scholar
MacDonald, T.J. et al. Expression profiling of medulloblastoma: PDGFRA and the RAS/MAPK pathway as therapeutic targets for metastatic disease. Nature Genet.29, 143–152 (2001). ArticleCAS Google Scholar
Pomeroy, S.L. et al. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature415, 436–442 (2002). ArticleCAS Google Scholar
Jazaeri, A.A. et al. Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers. J. Natl Cancer Inst.94, 990–1000 (2002). ArticleCAS Google Scholar
Welsh, J.B. et al. Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer. Proc. Natl Acad. Sci. USA98, 1176–1181 (2001). ArticleCAS Google Scholar
Wang, K. et al. Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray. Gene229, 101–108 (1999). ArticleCAS Google Scholar
Beer, D.G. et al. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nature Med.8, 816–824 (2002). ArticleCAS Google Scholar
Garber, M.E. et al. Diversity of gene expression in adenocarcinoma of the lung. Proc. Natl Acad. Sci. USA98, 13784–13789 (2001). ArticleCAS Google Scholar
Bhattacharjee, A. et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc. Natl Acad. Sci. USA98, 13790–13795 (2001). ArticleCAS Google Scholar
Zou, T.T. et al. Application of cDNA microarrays to generate a molecular taxonomy capable of distinguishing between colon cancer and normal colon. Oncogene21, 4855–4862 (2002). ArticleCAS Google Scholar
Lin, Y.M. et al. Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomas. Oncogene21, 4120–4128 (2002). ArticleCAS Google Scholar
Alon, U. et al. Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proc. Natl Acad. Sci. USA96, 6745–6750 (1999). ArticleCAS Google Scholar
Takahashi, M. et al. Gene expression profiling of clear cell renal cell carcinoma: gene identification and prognostic classification. Proc. Natl Acad. Sci. USA98, 9754–9759 (2001). ArticleCAS Google Scholar
Singh, D. et al. Gene expression correlates of clinical prostate cancer behavior. Cancer Cell1, 203–209 (2002). ArticleCAS Google Scholar
LaTulippe, E. et al. Comprehensive gene expression analysis of prostate cancer reveals distinct transcriptional programs associated with metastatic disease. Cancer Res.62, 4499–4506 (2002). CAS Google Scholar
Welsh, J.B. et al. Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer. Cancer Res.61, 5974–5978 (2001). CAS Google Scholar
Dhanasekaran, S.M. et al. Delineation of prognostic biomarkers in prostate cancer. Nature412, 822–826 (2001). ArticleCAS Google Scholar
Hippo, Y. et al. Global gene expression analysis of gastric cancer by oligonucleotide microarrays. Cancer Res.62, 233–240 (2002). CAS Google Scholar
Yeoh, E.J. et al. Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling. Cancer Cell1, 133–143 (2002). ArticleCAS Google Scholar
Hofmann, W.K. et al. Relation between resistance of Philadelphia-chromosome-positive acute lymphoblastic leukaemia to the tyrosine kinase inhibitor STI571 and gene-expression profiles: a gene-expression study. Lancet359, 481–486 (2002). ArticleCAS Google Scholar
Ferrando, A.A. et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell1, 75–87 (2002). ArticleCAS Google Scholar
Shipp, M.A. et al. Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nature Med.8, 68–74 (2002). ArticleCAS Google Scholar
Rosenwald, A. et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N. Engl. J. Med.346, 1937–1947 (2002). Article Google Scholar
Alizadeh, A.A. et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature403, 503–511 (2000). ArticleCAS Google Scholar
Hanahan, D. & Weinberg, R.A. The hallmarks of cancer. Cell100, 57–70 (2000). ArticleCAS Google Scholar
Ross, D.T. et al. Systematic variation in gene expression patterns in human cancer cell lines. Nature Genet.24, 227–235 (2000). ArticleCAS Google Scholar
Slonim, D.K. From patterns to pathways: gene expression data analysis comes of age. Nature Genet.32, 502–508 (2002). ArticleCAS Google Scholar
Churchill, G.A. Fundamentals of experimental design for cDNA microarrays. Nature Genet.32, 490–495 (2002). ArticleCAS Google Scholar
Ramaswamy, S. et al. Multiclass cancer diagnosis using tumor gene expression signatures. Proc. Natl Acad. Sci. USA98, 15149–15154 (2001). ArticleCAS Google Scholar
Eisen, M.B., Spellman, P.T., Brown, P.O. & Botstein, D. Cluster analysis and display of genome-wide expression patterns. Proc. Natl Acad. Sci. USA95, 14863–14868 (1998). ArticleCAS Google Scholar
Tusher, V., Tibshirani, R. & Chu, G. Significance analysis of microarrays applied to the ionizing radiation response. Proc. Natl Acad. Sci. USA98, 5116–5121 (2001). ArticleCAS Google Scholar
Tibshirani, R., Hastie, T., Narasimhan, B. & Chu, G. Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc. Natl Acad. Sci. USA99, 6567–6572 (2002). ArticleCAS Google Scholar
Chen, X. et al. Gene expression patterns in human liver cancers. Mol. Biol. Cell13, 1929–1939 (2002). ArticleCAS Google Scholar
Nielsen, T.O. et al. Molecular characterisation of soft tissue tumours: a gene expression study. Lancet359, 1301–1307 (2002). ArticleCAS Google Scholar
Wigle, D.A. et al. Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Res.62, 3005–3008 (2002). CAS Google Scholar
Bernards, R. & Weinberg, R.A. A progression puzzle. Nature418, 823 (2002).
Fisher, B. et al. A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen-receptor-positive tumors. N. Engl. J. Med.320, 479–484 (1989). ArticleCAS Google Scholar
Druker, B.J. et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N. Engl. J. Med.344, 1038–1042 (2001). ArticleCAS Google Scholar
Dematteo, R.P., Heinrich, M.C., El-Rifai, W.M. & Demetri, G. Clinical management of gastrointestinal stromal tumors: before and after STI-571. Hum. Pathol.33, 466–477 (2002). ArticleCAS Google Scholar
Su, A.I. et al. Molecular classification of human carcinomas by use of gene expression signatures. Cancer Res.61, 7388–7393 (2001). CAS Google Scholar
Hsiao, L.L. et al. A compendium of gene expression in normal human tissues. Physiol. Genom.7, 97–104 (2001). ArticleCAS Google Scholar
Perou, C.M. et al. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc. Natl Acad. Sci. USA96, 9212–9217 (1999). ArticleCAS Google Scholar
Rickman, D.S. et al. Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. Cancer Res.61, 6885–6891 (2001). CAS Google Scholar
Whitfield, M.L. et al. Identification of genes periodically expressed in the human cell cycle and their expression in tumors. Mol. Biol. Cell13, 1977–2000 (2002). ArticleCAS Google Scholar