Conversion of biliary system to pancreatic tissue in Hes1-deficient mice (original) (raw)

• Sasai, Y., Kageyama, R., Tagawa, Y., Shigemoto, R. & Nakanishi, S. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 6, 2620–2634 (1992).
  Article CAS Google Scholar
• Ishibashi, M. et al. Targeted disruption of mammalian hairy and Enhancer of split homolog-1 (HES-1) leads to up-regulation of neural helix-loop-helix factors, premature neurogenesis, and severe neural tube defects. Genes Dev. 9, 3136–3148 (1995).
  Article CAS Google Scholar
• Sommer, L., Ma, Q. & Anderson, D.J. Neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol. Cell Neurosci. 8, 221–241 (1996).
  Article CAS Google Scholar
• Jarriault, S. et al. Signalling downstream of activated mammalian Notch. Nature 377, 355–358 (1995).
  Article CAS Google Scholar
• Jensen, J. et al. Control of endodermal endocrine development by Hes-1. Nat. Genet. 24, 36–44 (2000).
  Article CAS Google Scholar
• Skipper, M. & Lewis, J. Getting to the guts of enteroendocrine differentiation. Nat. Genet. 24, 3–4 (2000).
  Article CAS Google Scholar
• Apelqvist, A. et al. Notch signalling controls pancreatic cell differentiation. Nature 400, 877–881 (1999).
  Article CAS Google Scholar
• Edlund, H. Pancreatic organogenesis—developmental mechanisms and implications for therapy. Nat. Rev. Genet. 3, 524–532 (2002).
  Article CAS Google Scholar
• Li, L. et al. Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1. Nat. Genet. 16, 243–251 (1997).
  Article CAS Google Scholar
• Oda, T. et al. Mutations in the human Jagged1 gene are responsible for Alagille syndrome. Nat. Genet. 16, 235–242 (1997).
  Article CAS Google Scholar
• Alagille, D., Odievre, M., Gautier, M. & Dommergues, J.P. Hepatic ductular hypoplasia associated with characteristic facies, vertebral malformations, retarded physical, mental, and sexual development, and cardiac murmur. J. Pediatr. 86, 63–71 (1975).
  Article CAS Google Scholar
• Gradwohl, G., Dierich, A., LeMeur, M. & Guillemot, F. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Natl. Acad. Sci. USA 97, 1607–1611 (2000).
  Article CAS Google Scholar
• Schwitzgebel, V.M. et al. Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 127, 3533–3542 (2000).
  CAS PubMed Google Scholar
• Ohtsuka, T. et al. Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation. EMBO J. 18, 2196–2207 (1999).
  Article CAS Google Scholar
• Shiojiri, N. & Katayama, H. Development of Dolichos biflorus agglutinin (DBA) binding sites in the bile duct of the embryonic mouse liver. Anat. Embryol. (Berl.) 178, 15–20 (1988).
  Article CAS Google Scholar
• Pang, K., Mukonoweshuro, C. & Wong, G.G. Beta cells arise from glucose transporter type 2 (Glut2)-expressing epithelial cells of the developing rat pancreas. Proc. Natl. Acad. Sci. USA 91, 9559–9563 (1994).
  Article CAS Google Scholar
• Herrera, P.L. Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development 127, 2317–2322 (2000).
  CAS PubMed Google Scholar
• Ahlgren, U., Pfaff, S.L., Jessell, T.M., Edlund, T. & Edlund, H. Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Nature 385, 257–260 (1997).
  Article CAS Google Scholar
• Elliott, W.M. & Youson, J.H. Development of the adult endocrine pancreas during metamorphosis in the sea lamprey, Petromyzon marinus L. II. Electron microscopy and immunocytochemistry. Anat. Rec. 237, 271–290 (1993).
  Article CAS Google Scholar
• Kawaguchi, Y. et al. The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat. Genet. 32, 128–134 (2002).
  Article CAS Google Scholar
• Golosow, N. & Grobstein, C. Epitheliomesenchymal interaction in pancreatic morphogenesis. Dev. Biol. 4, 242–255 (1962).
  Article CAS Google Scholar
• Kim, S.K. & Hebrok, M. Intercellular signals regulating pancreas development and function. Genes Dev. 15, 111–127 (2001).
  Article CAS Google Scholar
• Zaret, K.S. Hepatocyte differentiation: from the endoderm and beyond. Curr. Opin. Genet. Dev. 11, 568–574 (2001).
  Article CAS Google Scholar
• Ohlsson, H., Karlsson, K. & Edlund, T. IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO J. 12, 4251–4259 (1993).
  Article CAS Google Scholar
• Ahlgren, U., Jonsson, J. & Edlund, H. The morphogenesis of the pancreatic mesenchyme is uncoupled from that of the pancreatic epithelium in IPF1/PDX1-deficient mice. Development 122, 1409–1416 (1996).
  CAS PubMed Google Scholar
• Lee, J.C. et al. Regulation of the pancreatic pro-endocrine gene Neurogenin3. Diabetes 50, 928–936 (2001).
  Article CAS Google Scholar
• Kaneta, M. et al. A role for Pref-1 and HES-1 in thymocyte development. J. Immunol. 164, 256–264 (2000).
  Article CAS Google Scholar
• Tomita, K., Moriyoshi, K., Nakanishi, S., Guillemot, F. & Kageyama, R. Mammalian achaete-scute and atonal homologs regulate neuronal versus glial fate determination in the central nervous system. EMBO J. 19, 5460–5472 (2000).
  Article CAS Google Scholar