Inactivation of WT1 in nephrogenic rests, genetic precursors to Wilms' tumour (original) (raw)

• Beckwith, J., Kiviat, N. & Bonadio, J. Nephrogenic rests, nephroblastomatosis and the pathogenesis of Wilms' tumor. Ped. Pathol. 10, 1–36 (1990).
  Article CAS Google Scholar
• Bove, K. & McAdams, A. Multifocal nephroblastic neoplasia. J. natn. Cancer Inst. 61, 285–294 (1978).
  CAS Google Scholar
• Bove, K. & McAdams, A. The nephroblastomatosis complex and its relationship to Wilms' tumor: a clinicopathologic treatise. Perspect. pediatr. Pathol. 3, 185–223 (1976).
  CAS PubMed Google Scholar
• Knudson, A. & Strong, L. Mutation and cancer: a model for Wilms' tumor of the kidney. J. natn. Cancer Inst. 48, 313–324 (1972).
  Google Scholar
• Haber, D. & Housman, D. The genetics of Wilms' tumor. Adv. cancer Res. 59, 41–68 (1992).
  Article CAS Google Scholar
• Call, K. et al. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell 60, 509–520 (1990).
  Article CAS Google Scholar
• Gessler, M. et al. Homozygous deletion in Wilms' tumours of a zinc-finger gene identified by chromosome jumping. Nature 343, 774–778 (1990).
  Article CAS Google Scholar
• Pritchard-Jones, K. et al. The candidate Wilms' tumour gene is involved in genitourinary development. Nature 346, 194–197 (1990).
  Article CAS Google Scholar
• Buckler, A., Pelletier, J., Haber, D., Glaser, T. & Housman, D. Isolation, characterization, and expression of the murine Wilms' tumor gene (WT1) during kidney development. Molec. Cell Biol. 11, 1707–1712 (1991).
  Article CAS Google Scholar
• Haber, D. et al. An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor. Cell 61, 1257–1269 (1990).
  Article CAS Google Scholar
• Cowell, J. et al. Structural rearrangements of the WT1 gene in Wilms' tumor cells. Oncogene 6, 595–599 (1991).
  CAS PubMed Google Scholar
• Ton, C. et al. Smallest region of overlap in Wilms' tumor deletions uniquely implicates an 11p13 zinc finger gene as the disease locus. Genomics 10, 293–297 (1991).
  Article CAS Google Scholar
• Little, M. et al. Zinc finger point mutations within the WT1 gene in Wilms' tumor patients. Proc. natn. Acad. Sci. U.S.A. 88, 4791–4795 (1992).
  Article Google Scholar
• Huff, V. et al. Evidence for WT1 as a Wilms' tumor (WT) gene: intragenic germinal deletion in bilateral WT. Am. J. hum. Genet. 48, 997–1003 (1991).
  CAS PubMed PubMed Central Google Scholar
• Pelletier, J. et al. WT1 mutations contribute to abnormal genital system development and hereditary Wilms' tumour. Nature 353, 431–434 (1991).
  Article CAS Google Scholar
• Pelletier, J. et al. Germline mutations in the Wilms' tumor suppressor gene are associated with abnormal urogenital development in Denys-Drash syndrome. Cell 67, 437–447 (1991).
  Article CAS Google Scholar
• Henry, I. et al. Tumor-specific loss of 11 p15.5 alleles in del 11p13 Wilms' tumor and in familial adrenocorical carcinoma. Proc. natn. Acad. Sci. U.S.A. 86, 3247–3251 (1989).
  Article CAS Google Scholar
• Riccardi, V., Sujansky, E., Smith, A. & Francke, U. Chromosomal imbalance in the aniridia-Wilms' tumor association: 11 p interstitial deletion. Pediatrics 61, 604–610 (1978).
  CAS PubMed Google Scholar
• Wiedemann, H. Complexe malformatif familial avec hernie ombilicale et macroglossie—Un syndrome nouveau? J. Genet. hum. 13, 223–232 (1964).
  CAS PubMed Google Scholar
• Beckwith, J. Macroglossia, omphalocele, adrenal cytomegaly, gigantism and hyperplastic visceromegaly. Birth Defects 5, 188–196 (1969).
  Google Scholar
• Bove, K.E. & Kiser, B. AgNOR counts in multicentric Wilms' tumor distinguish maturing, dormant and expanding cell populations. Lab. Invest. 64, 2A (1991).
  Google Scholar
• Pritchard-Jones, K. & Fleming, S. Cell types expressing the Wilms' tumour gene (WT1) in Wilms' tumour: implications for tumor histogenesis. Oncogene 6, 2211–210 (1991).
  CAS PubMed Google Scholar
• Mulvihill, D.M., Mercado, M.G. & Boinaeau, F.G. Beckwith-Wiedemann syndrome and its association with Type II polycystic kidney disease. Pediatr. Nephrol. 3, 286–289 (1989).
  Article CAS Google Scholar
• Haber, D. et al. Alternative splicing and genomic structure of the Wilms' tumor gene WT1. Proc. natn. Acad. Sci. U.S.A. 88, 9618–9622 (1991).
  Article CAS Google Scholar
• Orita, N., Iwahana, H., Kanazawa, H., Hayashi, K. & Sekiya, T. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. natn. Acad. Sci. U.S.A. 86, 2766–2770 (1989).
  Article CAS Google Scholar
• Haber, D., Timmers, H., Pelletier, J., Sharp, P. & Housman, D. A dominant mutation in the Wilms' tumor gene WT1 cooperates with the viral oncogene E1A in transformation of primary kidney cells. Proc. natn. Acad. Sci. U.S.A. 89, 6010–6014 (1992).
  Article CAS Google Scholar
• Sidransky, D. et al. Clonal origin of bladder cancer. New Engl. J. Med. 326, 737–740 (1992).
  Article CAS Google Scholar
• Fearon, E. & Vogelstein, B. Agenetic model for colorectal tumorigenesis. Cell 61, 759–767 (1990).
  Article CAS Google Scholar
• Costanzi, E., da Silva Fernandes, M. & Erwenne, C. Esterase D in retinoma. Ophtalmic paed. Genet. 10, 157–160 (1989).
  Article CAS Google Scholar
• Balmer, A., Munier, F. & Gailloud, C. Retinoma case studies. Ophthalmic paed. Genet. 12, 131–137 (1991).
  Article CAS Google Scholar
• Haber, D. & Housman, D. Rate-limiting steps: the genetics of pediatric cancers. Cell 64, 5–8 (1991).
  Article CAS Google Scholar