Alternative splicing and genome complexity (original) (raw)
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- Published: 17 December 2001
Nature Genetics volume 30, pages 29–30 (2002)Cite this article
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Abstract
Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.
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Authors and Affiliations
- Max Delbrück Center for Molecular Medicine, Robert-Rössle Strasse 10, Berlin-Buch, 13125, Germany
David Brett, Heike Pospisil, Jens Reich & Peer Bork - European Molecular Biology Laboratory, Meyerhofstr. 1, Heidelberg, 69012, Germany
Juan Valcárcel & Peer Bork
Authors
- David Brett
You can also search for this author inPubMed Google Scholar - Heike Pospisil
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Brett, D., Pospisil, H., Valcárcel, J. et al. Alternative splicing and genome complexity.Nat Genet 30, 29–30 (2002). https://doi.org/10.1038/ng803
- Received: 18 July 2001
- Accepted: 26 November 2001
- Published: 17 December 2001
- Issue Date: January 2002
- DOI: https://doi.org/10.1038/ng803