Alternative splicing and genome complexity (original) (raw)

Nature Genetics volume 30, pages 29–30 (2002)Cite this article

Abstract

Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.

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Authors and Affiliations

  1. Max Delbrück Center for Molecular Medicine, Robert-Rössle Strasse 10, Berlin-Buch, 13125, Germany
    David Brett, Heike Pospisil, Jens Reich & Peer Bork
  2. European Molecular Biology Laboratory, Meyerhofstr. 1, Heidelberg, 69012, Germany
    Juan Valcárcel & Peer Bork

Authors

  1. David Brett
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  2. Heike Pospisil
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  3. Juan Valcárcel
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  4. Jens Reich
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  5. Peer Bork
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Brett, D., Pospisil, H., Valcárcel, J. et al. Alternative splicing and genome complexity.Nat Genet 30, 29–30 (2002). https://doi.org/10.1038/ng803

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