Immunotherapy through TCR gene transfer (original) (raw)
Mueller, N. Overview of the epidemiology of malignancy in immune deficiency. J. Acquir. Immune Defic. Syndr.21, S5–10 (1999). PubMed Google Scholar
Shankaran, V. et al. IFNγ and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature410, 1107–1111 (2001). ArticleCAS Google Scholar
Kolb, H. J. et al. Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients. European Group for Blood and Marrow Transplantation Working Party Chronic Leukemia. Blood86, 2041–2050 (1995). CASPubMed Google Scholar
Collins, R. H. Jr et al. Donor leukocyte infusions in 140 patients with relapsed malignancy after allogeneic bone marrow transplantation. J. Clin. Oncol.15, 433–444 (1997). Article Google Scholar
Heslop, H. E. & Rooney, C. M. Adoptive cellular immunotherapy for EBV lymphoproliferative disease. Immunol. Rev.157, 217–222 (1997). ArticleCAS Google Scholar
Goulmy, E. et al. Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation. N. Engl. J. Med.334, 281–285 (1996). ArticleCAS Google Scholar
Dembic, Z. et al. Transfer of specificity by murine α and β T-cell receptor genes. Nature320, 232–238 (1986). ArticleCAS Google Scholar
Clay, T. M. et al. Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity. J. Immunol.163, 507–513 (1999). CASPubMed Google Scholar
Cooper, L. J., Kalos, M., Lewinsohn, D. A., Riddell, S. R. & Greenberg, P. D. Transfer of specificity for human immunodeficiency virus type 1 into primary human T lymphocytes by introduction of T-cell receptor genes. J. Virol.74, 8207–8212 (2000). ArticleCAS Google Scholar
Fujio, K. et al. Functional reconstitution of class II MHC-restricted T cell immunity mediated by retroviral transfer of the α β TCR complex. J. Immunol.165, 528–532 (2000). ArticleCAS Google Scholar
Townsend, A. R., Gotch, F. M. & Davey, J. Cytotoxic T cells recognize fragments of the influenza nucleoprotein. Cell42, 457–467 (1985). ArticleCAS Google Scholar
Kitamura, T. New experimental approaches in retrovirus-mediated expression screening. Int. J. Hematol.67, 351–359 (1998). ArticleCAS Google Scholar
Flynn, K. J. et al. Virus-specific CD8+ T cells in primary and secondary influenza pneumonia. Immunity8, 683–691 (1998). ArticleCAS Google Scholar
Haanen, J. B. et al. Systemic T cell expansion during localized viral infection. Eur. J. Immunol.29, 1168–1174 (1999). ArticleCAS Google Scholar
Belz, G. T., Altman, J. D. & Doherty, P. C. Characteristics of virus-specific CD8(+) T cells in the liver during the control and resolution phases of influenza pneumonia. Proc. Natl Acad. Sci. USA95, 13812–13817 (1998). ArticleCAS Google Scholar
Whitmire, J. K. & Ahmed, R. Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses. Curr. Opin. Immunol.12, 448–455 (2000). ArticleCAS Google Scholar
Sandberg, J. K. et al. Superdominance among immunodominant H-2Kb-restricted epitopes and reversal by dendritic cell-mediated antigen delivery. J. Immunol.160, 3163–3169 (1998). CASPubMed Google Scholar
Murphy, W. J. & Blazar, B. R. New strategies for preventing graft-versus-host disease. Curr. Opin. Immunol.11, 509–515 (1999). ArticleCAS Google Scholar
Heikkinen, T. & Chonmaitree, T. Increasing importance of viruses in acute otitis media. Ann. Med.32, 157–163 (2000). ArticleCAS Google Scholar
Glezen, W. P. Prevention of acute otitis media by prophylaxis and treatment of influenza virus infections. Vaccine19, S56–58 (2000). ArticleCAS Google Scholar
Busch, D. H. & Pamer, E. G. T cell affinity maturation by selective expansion during infection. J. Exp. Med.189, 701–710 (1999). ArticleCAS Google Scholar
Jahner, D. et al. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature298, 623–628 (1982). ArticleCAS Google Scholar
Challita, P. M. & Kohn, D. B. Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo. Proc. Natl Acad. Sci. USA91, 2567–2571 (1994). ArticleCAS Google Scholar
Robbins, P. B. et al. Consistent, persistent expression from modified retroviral vectors in murine hematopoietic stem cells. Proc. Natl Acad. Sci. USA95, 10182–10187 (1998). ArticleCAS Google Scholar
May, C. et al. Therapeutic haemoglobin synthesis in β-thalassaemic mice expressing lentivirus-encoded human β-globin. Nature406, 82–86 (2000). ArticleCAS Google Scholar
Hekele, A. et al. Growth retardation of tumors by adoptive transfer of cytotoxic T lymphocytes reprogrammed by CD44v6-specific scFv:η-chimera. Int. J. Cancer68, 232–238 (1996). ArticleCAS Google Scholar
Altenschmidt, U., Klundt, E. & Groner, B. Adoptive transfer of in vitro -targeted, activated T lymphocytes results in total tumor regression. J. Immunol.159, 5509–5515 (1997). CASPubMed Google Scholar
Willemsen, R. A. et al. Grafting primary human T lymphocytes with cancer-specific chimeric single chain and two chain TCR. Gene Ther.7, 1369–1377 (2000). ArticleCAS Google Scholar
Viola, A. & Lanzavecchia, A. T cell activation determined by T cell receptor number and tunable thresholds. Science273, 104–106 (1996). ArticleCAS Google Scholar
Kalergis, A. M. et al. Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex. Nature Immunol.2, 229–234 (2001). ArticleCAS Google Scholar
Backstrom, B. T. et al. A motif within the T cell receptor α chain constant region connecting peptide domain controls antigen responsiveness. Immunity5, 437–447 (1996). ArticleCAS Google Scholar
Ulivieri, C., Peter, A., Orsini, E., Palmer, E. & Baldari, C. T. Defective Signaling to Fyn by a T Cell Antigen Receptor Lacking the α-Chain Connecting Peptide Motif. J. Biol. Chem.276, 3574–3580 (2001). ArticleCAS Google Scholar
Holler, P. D. et al. In vitro evolution of a T cell receptor with high affinity for peptide/MHC. Proc. Natl Acad. Sci. USA97, 5387–5392 (2000). ArticleCAS Google Scholar
Kessels, H. W., van den Boom, M. D., Spits, H., Hooijberg, E. & Schumacher, T. N. Changing T cell specificity by retroviral T cell receptor display. Proc. Natl Acad. Sci. USA97, 14578–14583 (2000). ArticleCAS Google Scholar
Stanislawski, T. et al. Circumventing tolerance to a human mdm2 derived tumor antigen by TCR gene transfer. Nature Immunol.2, 962–970 (2001). ArticleCAS Google Scholar
Atwell, S., Ridgway, J. B., Wells, J. A. & Carter, P. Stable heterodimers from remodeling the domain interface of a homodimer using a phage display library. J. Mol. Biol.270, 26–35 (1997). ArticleCAS Google Scholar
Muller, A. et al. Involvement of chemokine receptors in breast cancer metastasis. Nature410, 50–56 (2001). ArticleCAS Google Scholar
Altman, J. D. et al. Phenotypic analysis of antigen-specific T lymphocytes. Science274, 94–96 (1996). ArticleCAS Google Scholar
Gorer, P. A. Studies in antibody response of mice to tumour inoculation. Br. J. Cancer4, 372–379 (1950). ArticleCAS Google Scholar
Harrison, P. T. An ethanol-acetic acid-formol saline fixative for routine use with special application to the fixation of non-perfused rat lung. Lab. Anim.18, 325–331 (1984) ArticleCAS Google Scholar