Angiogenesis in cancer, vascular, rheumatoid and other disease (original) (raw)

References

  1. Demicheli, R. et al. Local recurrences following mastectomy: support for the concept of tumor dormancy.J, natn. Cancer Inst. 86, 45–48 (1994).
    Article CAS Google Scholar
  2. Morrow, M. & Jordan, V.C. Risk factors and the prevention of breast cancer with tamoxifen. Cancer Surveys 18, 211–229 (1993).
    CAS PubMed Google Scholar
  3. Kripke, M.L. Immunoregulation of carcinogenesis: past, present, and future. J. natn. Cancer Inst. 80, 722–727 (1988).
    Article CAS Google Scholar
  4. Sugarbaker, E.V. Cancer metastasis: a product of tumor-host interactions. Curr. Prob. Cancer 3, 1–59 (1979).
    Article CAS Google Scholar
  5. Fider, I.J. & Ellis, L.M. Cell 79, 185–188 (1994).
    Article Google Scholar
  6. Prehn, R.T. The inhibition of tumor growth by tumor mass. Cancer Res. 51, 2–4 (1991).
    CAS PubMed Google Scholar
  7. Folkman, J., Watson, K. Ingber & D. Hanahan, D. Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature 339, 58–61 (1989).
    Article CAS Google Scholar
  8. Kandel, J. et al. Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma. Cell 66, 1095–1104 (1991).
    Article CAS Google Scholar
  9. Weidner, N., Semple, J., Welch, W. & Folkman, J. Tumor angiogenesis correlates with metastasis in invasive breast carcinoma. N. Engl. J. Med. 324, 1–8 (1991).
    Article CAS Google Scholar
  10. Folkman, J. Tumor angiogenesis. In: Mendelsohn, J., Howley, P., Liotta, L., Israel, M., eds. The Molecular Basis of Cancer, W.B. Saunders Company, Philadelphia, in press (1994).
    Google Scholar
  11. Folkman, J. Angiogenesis and breast cancer. J. clin. Oncol 12, 441–443 (1994).
    Article CAS Google Scholar
  12. Nicosia, R.F., Tchao, R. & Leighton, J. Interactions between newly formed en-dothelial channels and carcinoma cells in plasma clot culture. Clin. exp. Metastasis. 4, 91–104 (1986).
    Article CAS Google Scholar
  13. Rak, J.W., Hegmann, E.J., Lu, C. & Kerbel, R.S. Progressive loss of sensitivity to en-dothelium-derived growth inhibitors expressed by human melanoma cells during disease progression. J. cell. Physiol. 159, 245–255 (1994).
    Article CAS Google Scholar
  14. Hamada, J., Cavanaugh, P.G., Lotan, O. & Nicolson, G. Separable growth and migration factors for large-cell lymphoma cells secreted by microvascular endothe-lial cells derived from target organs for metastasis. Br. J. Cancer 66, 349–354 (1992).
    Article CAS Google Scholar
  15. Rastinejad, F., Polveini, P.J. & Bouck, N.P. Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene. Cell 56, 345–355 (1989).
    Article CAS Google Scholar
  16. Bouck, N.P. Tumor angiogenesis: the role of oncogenes and tumor suppressor gene. Cancer Cells. 2, 179–185 (1990).
    CAS PubMed Google Scholar
  17. Dameron, K.M., Volpert, O.V., Tainsky, M.A. & Bouck, N.P. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265, 1582–1584 (1994).
    Article CAS Google Scholar
  18. Maciag, T., Mehlman, T., Friesel, R. & Schreiber, A. Heparin binds endothelial cell growth factor, the principal endothelial cell mitogen in bovine brain. Science 225, 932–935 (1984).
    Article CAS Google Scholar
  19. Shing, Y. et al. Heparin affinity: purification of a tumor-derived capillary endothelial cell growth factor. Science 223, 1296–1298 (1984).
    Article CAS Google Scholar
  20. Ferrara, N. & Henzel, W.J. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem. Biophys. Res. Com-mun. 161, 851–855 (1989).
    CAS Google Scholar
  21. Fett, J.W. et al. Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells. Biochem. 24, 5480–5486 (1985).
    Article CAS Google Scholar
  22. Folkman, J., Shing, Y., J. biol Chem. 267, 10931–10934 (1992).
    CAS PubMed Google Scholar
  23. O'Reilly, S. et al. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315–328 (1994).
    Article CAS Google Scholar
  24. Van Meir, E.G. et al. Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells. Nature Genetics 8, 171–176 (1994).
    Article CAS Google Scholar
  25. Poste, G. & Fidler, I.J. The pathogenesis of cancer metastasis. Nature 283, 139–146 (1980).
    Article CAS Google Scholar
  26. Zetter, B. The cellular basis of site-specific tumor metastasis. N. Engl. J. Med. 322, 605–612 (1990).
    Article CAS Google Scholar
  27. Holmgren, L., O'Reilly, M. & Folkman, J. in press (1994).
  28. Takeshita, S. et al. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model. J. clin. Invest 93, 662–670 (1994).
    Article CAS Google Scholar
  29. Shweiki, D., Itin, A., Soffer, D. & Keshet, E. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359, 843–845 (1992).
    Article CAS Google Scholar
  30. Ferrara, N. personal communication (1994).
  31. Yuhas, J.M. & Pazmino, N.H. Inhibition of subcutaneously growing line 1 carcinomas due to metastatic spread. Cancer Res. 34, 2005–2010 (1974).
    CAS PubMed Google Scholar
  32. Nanus, D. et al. Expression of basic fibroblast growth factor in primary human renal tumors: correlation with poor survival. J. natn. Cancer Inst. 85, 1597–1599 (1993).
    Article CAS Google Scholar
  33. Nguyen, M. et al. Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers. J. natn. Cancer Inst. 86, 356–361 (1994).
    Article CAS Google Scholar
  34. Kohn, E. et al. Phase I trial of signal transduction inhibitor, CAI. Proc. Amer. Assoc. Cancer Res. 35,244(1994).
  35. Liotta, L.A. personal communication (1994).
  36. Folkman, J. Clinical applications of angiogenesis research. New Engl. J. Med. in press (1994).
  37. Watanabe, H., Nguyen, M., Schizer, M., Li, V., Hayes, D.R., Sallan, S., Folkman, J. Basic fibroblast growth factor in human serum – a prognostic test for breast cancer. Molec. Biol. Cell 3, 324a (1992).
    Google Scholar
  38. Li, V.W. et al. Microvessel count and cerebrospinal fluid basic fibroblast growth factor in children with brain tumors. The Lancet 344, 82–86 (1994).
    Article CAS Google Scholar
  39. Weidner, N. et al. Tumor angiogenesis: A new significant and independent prognostic indicator in early-stage breast carcinoma. J. natn. Cancer Inst. 84, 1875–1887 (1992).
    Article CAS Google Scholar
  40. Weidner, N., Carroll, P.R., Flax, J., Blumenfeld, W. & Folkman, J. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma. Amer. J. Pathol. 143, 401–409 (1993).
    CAS Google Scholar
  41. Teicher, B.A. et al. Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents. Int. J. Cancer. 57, 920–925 (1994).
    Article CAS Google Scholar
  42. Schaper, W., Schaper, J. Collateral Circulation: Heart, Brain, Kidney, Limbs. Kluwer Academic Publishers, Boston, (1993).
    Book Google Scholar
  43. Miller, J.W. et al. Vascular endothelial growth factorJVascular permeability factor is temporally and spatially correlated with ocular angiogenesis in a primate model. Amer. J. Pathol 145, 574–584 (1994).
    CAS Google Scholar
  44. Adamis, A.P. et al. Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy. Amer. J. Ophthal. 118, 445–450(1994).
    Article CAS Google Scholar
  45. Takahashi, K. et al. Cellular markers that distinguish the phases of hemangioma during infancy and childhood. J. clin. Invest. 93, 2357–2364 (1994).
    Article CAS Google Scholar
  46. Peacock, D.J., Banquerigo, M.L. & Brahn, E. Angiogenesis inhibition suppresses collagen arthritis. J. exp. Med. 175, 1135–1138 (1992).
    Article CAS Google Scholar
  47. Nickoloff, B.J., Mitra, R.S., Varani, J., Dixit, V.M. & Polerini, P.J. Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis. Amer. J. Pathol 44, 820–828 (1994).
    Google Scholar
  48. Bacharach-Buhles, M., Panz, B., Elgammal, S., Auer, T. & Altmeyer, P. The elongation of psoriatic capillaries, the result of epidermal hyperplasia, not of angiogenesis. J. Invest. Dermatol. 103, 263 (1994).
    Google Scholar
  49. Szabo, S. Animal model: cysteamine-induced and chronic duodenal ulcer in the rat. Amer. J. Pathol 93, 273–276 (1974).
    Google Scholar
  50. Szabo, S. et al. Orally administered FGF mutein: Effect on healing of chronic duodenal ulcers in rats. Digestive Disease and Sciences 34, 1323 (1989).
    Google Scholar
  51. Folkman, J. et al. Duodenal ulcer: discovery of a new mechanism and development of angiogenic therapy which accelerates healing. Ann. Surg. 214, 414–427 (1991).
    Article CAS Google Scholar
  52. Hull, M.A., Cullen, D.J.E. & Hawkey, C.J. Basic fibroblast growth factor in gastric ulceration: mucosal levels and therapeutic potential. Gastroenterology 106, A97 (1994).
  53. Dvorak, H., Wounds that do not heal. Similarities between tumor stroma generation and wound healing. N. EnglJ. Med. 315, 1650–1659 (1986).
    Article CAS Google Scholar
  54. Wolfe, M.M. et al. Safety and efficacy of an angiogenic peptide, basic fibroblast growth factor (bFGF) in the treatment of gastroduodenal ulcers: A preliminary report. Gastroenterology 106, A212 (1994).
    Google Scholar
  55. Folkman, J. Angiogenesis in female reproductive organs. In: Steroid Hormones and Uterine Bleeding. Alexander, N.J., d'Arcangues, C., eds. American Association for the Advancement of Science Press, Washington DC, 144–158 (1992).
    Google Scholar
  56. Ravindranath, N., Little-Ihrig, L., Philips, H.S., Ferrara, N. & Zeleznik, A. Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary. Endocrinology 131, 254–260 (1992).
    Article CAS Google Scholar
  57. Redmer, D.A., Kirsch, J.D. & Reynolds, L.P. Production of mitogenic factors by cell types of bovine large estrogen-active and estrogen-inactive follicles. J. Anim. Sci. 69, 237–245 (1991).
    Article CAS Google Scholar
  58. Reynolds, L.P., Killilea, D.S. & Redmer, D.A. Angiogenesis in the female reproductive system. FASEB 6, 886–892 (1992).
    Article CAS Google Scholar
  59. Greenwald, G.S. Temporal and topographic changes in DNA synthesis after induced follicular atresia. Biol. Reprod. 40, 175–181 (1989).
    Article Google Scholar
  60. Folkman, J. What is the evidence that tumors are angiogenesis dependent? J. natn. Cancer Inst. 82, 4–6 (1990).
    Article CAS Google Scholar
  61. D'Amato, R.J., Loughnan, M.S., Flynn, E. & Folkman, J. Thalidomide is an inhibitor of angiogenesis. Proc. natn Acad. Sci.USA 91, 4082–4085 (1994).
    Article CAS Google Scholar
  62. Risau, W. & Ekblom, P. Production of a heparin-binding angiogenesis factor by the embryonic kidney. J. cell Biol 103, 1101–1107 (1986).
    Article CAS Google Scholar
  63. Millauer, B. et al. High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell 72, 835–846(1993).
    Article CAS Google Scholar
  64. Poole, T.J. & Coffin, J.D. Vasculogenesis and angiogenesis - two distant morpho-genetic mechanisms establish embryonic vascular pattern. J. exp. Zool 251, 224–231 (1989).
    Article CAS Google Scholar
  65. Liotta, L., Kleinerman, J. & Saidel, F. Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation. Cancer Res. 34, 997–1004 (1974).
    CAS PubMed Google Scholar
  66. Brem, H., Goto, F., Budson, A., Saunders, L. & Folkman, J. Minimal drug resistance after prolonged antiangiogenic therapy with AGM-1470. Surgical Forum XLV, 674–677 (1994).
    Google Scholar
  67. Plate, K.H., Breier, G., Welch, H.A. & Risau, W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359, 845–848, (1992).
    Article CAS Google Scholar
  68. Kerbel, R.S. Inhibition of tumour angiogenesis as a strategy to circumvent acquired resistance to anticancer therapeutic agents. BioEssays 13(1), 31–36 (1991).
    Article CAS Google Scholar
  69. Crowley, N.J. & Siegler, H.F. Relationship between disease-free interval and survival in patients with recurrent melanoma. Arch. Surg. 127, 1303–1308 (1992).
    Article CAS Google Scholar
  70. Ezekowitz, R.A.B., Mulliken, J.B., Folkman, J. Interferon alfa-2a therapy for life-threatening hemangiomas of infancy. New Engl. J. Med. 326, 1456–1463 (1992) (and corrections New Engl J. Med. 33, 300 (1994)).
    Article CAS Google Scholar
  71. Folkman, J. et al. (unpublished data).
  72. O'Reilly, M.S. et al. (unpublished data).

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