CREB family transcription factors inhibit neuronal suicide (original) (raw)

Nature Medicine volume 8, pages 450–451 (2002)Cite this article

Neurodenerative disorders such as Huntington disease lead to neuronal cell death in discrete regions of brain. A new study implicates the CREB transcription factor family as critical mediators that prevent such neuronal death.

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Figure 1: Under normal conditions, CREB family transcription factors promote expression of genes that contribute to neuronal survival.

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Authors and Affiliations

  1. Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ted M. Dawson
  2. Department of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ted M. Dawson & David D. Ginty
  3. Department of Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    David D. Ginty

Authors

  1. Ted M. Dawson
  2. David D. Ginty

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Dawson, T., Ginty, D. CREB family transcription factors inhibit neuronal suicide.Nat Med 8, 450–451 (2002). https://doi.org/10.1038/nm0502-450

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