Extensive polymorphisms observed in HIV–1 clade B protease gene using high–density oligonucleotide arrays (original) (raw)

References

  1. Kohl, N.E. et al. Active human immunodeficiency virus protease is required for viral infectivity. Proc. Natl. Acad. Sci. USA 85, 4686–4690 (1988).
    Article CAS Google Scholar
  2. LeGrice, S.F., Mills, J. & Mous, J. Active site mutations of AIDS virus protease and its alleviation by trans complementation. EMBO. J. 7 2547–2553 (1988).
    Article CAS Google Scholar
  3. Peng, C., Ho, B.K., Chang, T.W. & Chang, N.T. Role of human immunodeficiency virus type 1-specific protease in core protein maturation and viral infectivity. J. Virol. 63, 2550–2556 (1989).
    CAS PubMed PubMed Central Google Scholar
  4. Meyers, G. et al. (eds.) Human Retroviruses and AIDS, Vol. I, 79–83; vol. III, 97–106(Los Alamos National Laboratory, New Mexico, 1994).
    Google Scholar
  5. Miller, M., Jaskólski, M., Mohana Rao, J.K., Leis, J. & Wlodawer, A. Crystal structure of a retroviral protease proves relationship to aspartic protease family. Nature 337, 576–578 (1989).
    Article CAS Google Scholar
  6. Toh, H., Ono, M., Saigo, K. & Miyata, T. Retroviral protease-like sequence in yeast transposon Ty1 . Nature 315, 691 (1985).
    Article CAS Google Scholar
  7. Pillay, D., Bryant, M., Getman, D. & Richman, D.D. HIV-1 protease inhibitors: Their development, mechanism of action and clinical potential. Rev. Med. Virol. 5, 23–33 (1995).
    Article Google Scholar
  8. Mellors, J.W., Larder, B.A. & Schinazi, R.F. Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int. Antiviral News 3, 8–13 (1995).
    Google Scholar
  9. Condra, J.H. et al. In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors. Nature 374, 569–571 (1995).
    Article CAS Google Scholar
  10. Fodor, S.P. et al. Light-directed, spatially addressable parallel chemical synthesis. Science 251, 767–773 (1991).
    Article CAS Google Scholar
  11. Pease, A.C. et al. Light-generated oligonucleotide arrays for rapid DNA sequence analysis. Proc. Natl. Acad. Sci. USA 91, 5022–5026 (1994).
    Article CAS Google Scholar
  12. Lipshutz, R.J. Using oligonucleotide probe arrays to access genetic diversity. Biotechniques 19, 442–447 (1995).
    CAS PubMed Google Scholar
  13. Lipshutz, R.J. & Fodor, S.P.A. Advanced DNA sequencing technologies. Curr. Opin. Struct. Biol. 4, 376–380 (1994).
    Article CAS Google Scholar
  14. Rose, B. et al. in HIV Drug-Resistance Third International Workshop, p. 17, 2–5 August 1994, Kauai, Hawaii (1994).
  15. Kaplan, A.H. et al. Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease. Proc. Natl. Acad. Sci. USA 91, 5022–5026 (1994).
    Article Google Scholar
  16. Tisdale, M. in HIV Drug-Resistance Third International Workshop, p. 14, 2–5 August 1994, Kauai, Hawaii (1994).
    Google Scholar
  17. Sanchez-Pescador, R. et al. Nucleotide sequence and expression of an AIDS-associated retrovirus (ARV-2). Science 227, 484–492 (1985).
    Article CAS Google Scholar
  18. Theodore, T. & Buckler-White, A. in Human Retroviruses and AIDS (eds. Myers, G. et al.) 162–165 (Los Alamos National Laboratory, New Mexico, (1990).
    Google Scholar
  19. Ratner, L. et al. Complete nucleotide sequence of the AIDS virus, HTL-VIII. Nature 313, 277–284 (1985).
    Article CAS Google Scholar
  20. Gingeras, T.R. et al. Use of self-sustained sequence replication (3SR) amplification reaction to analyze and detect mutations in zidovudine-resistant human immunodeficiency virus. J. Infect. Dis. 164, 1066–1074 (1991).
    Article CAS Google Scholar
  21. Delwart, E.L. et al. Genetic relationships determined by a DNA heteroduplex mobility assay: Analysis of HIV-1 env genes. Science 262, 1257–1261 (1993).
    Article CAS Google Scholar
  22. Coffin, J.M. HIV population dynamics in vivo: Implications for genetic variation, pathogenesis, and therapy. Science 267, 483–489 (1995).
    Article CAS Google Scholar
  23. Ho, D.D. et al. Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetric protease inhibitor. J. Virol. 68, 2016–2020 (1994).
    CAS PubMed PubMed Central Google Scholar
  24. Eckert, K.A. & Kunkel, T.A. DNA polymerase fidelity and the polymerase chain reaction. PCR Methods Appl. 1, 17–24 (1991).
    Article CAS Google Scholar
  25. Tabor, S. & Richardson, C.C. A single hydroxyl moiety in a pol I-type DNA polymerase is responsible for distinguishing between deoxy-and dideoxynucleotides. Proc. Natl. Acad. Sci. USA 92, 6639–6643 (1995).
    Article Google Scholar
  26. Potts, K.E. et al. in HIV Drug-Resistance Third International Workshop, p. 4, 2–5 August 1994, Kauai, Hawaii (1994).
    Google Scholar
  27. Jacobsen, H. et al. in HIV Drug-Resistance Third International Workshop, p. 16, 2–5 August 1994, Kauai, Hawaii (1994).
    Google Scholar

Download references