Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease (original) (raw)
Teshima, T. & Ferrara, J.L. Understanding the alloresponse: new approaches to graft-versus-host disease prevention. Semin. Hematol.39, 15–22 (2002). Article Google Scholar
Ferrara, J.L., Levy, R. & Chao, N.J. Pathophysiologic mechanisms of acute graft-vs.-host disease. Biol. Blood Marrow Transplant.5, 347–356 (1999). ArticleCAS Google Scholar
Ho, V.T. & Soiffer, R.J. The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation. Blood98, 3192–3204 (2001). ArticleCAS Google Scholar
Shlomchik, W.D. et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science285, 412–415 (1999). ArticleCAS Google Scholar
Zhang, Y., Louboutin, J.P., Zhu, J., Rivera, A.J. & Emerson, S.G. Preterminal host dendritic cells in irradiated mice prime CD8+ T cell-mediated acute graft-versus-host disease. J. Clin. Invest.109, 1335–1344 (2002). ArticleCAS Google Scholar
Katz, S.I. & Breathnach, S.M. Immunopathology of cutaneous graft-versus-host disease. Am. J. Dermatopathol.9, 343–348 (1987). Article Google Scholar
Stingl, G., Tamaki, K. & Katz, S.I. Origin and function of epidermal Langerhans cells. Immunol. Rev.53, 149–174 (1980). ArticleCAS Google Scholar
Schuler, G. & Steinman, R.M. Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro . J. Exp. Med.161, 526–546 (1985). ArticleCAS Google Scholar
Banchereau, J. et al. Immunobiology of dendritic cells. Annu. Rev. Immunol.18, 767–811 (2000). ArticleCAS Google Scholar
Merad, M. et al. Langerhans cells renew in the skin throughout life under steady-state conditions. Nat. Immunol.3, 1135–1141 (2002). ArticleCAS Google Scholar
Zeng, D. et al. Bone marrow NK1.1− and NK1.1+ T cells reciprocally regulate acute graft versus host disease. J. Exp. Med.189, 1073–1081 (1999). ArticleCAS Google Scholar
Caux, C. et al. Dendritic cell biology and regulation of dendritic cell trafficking by chemokines. Springer Semin. Immunopathol.22, 345–369 (2000). ArticleCAS Google Scholar
Homey, B. et al. Up-regulation of macrophage inflammatory protein-3 α/CCL20 and CC chemokine receptor 6 in psoriasis. J. Immunol.164, 6621–6632 (2000). ArticleCAS Google Scholar
Katz, S.I., Tamaki, K. & Sachs, D.H. Epidermal Langerhans cells are derived from cells originating in bone marrow. Nature282, 324–326 (1979). ArticleCAS Google Scholar
Frelinger, J.G., Hood, L., Hill, S. & Frelinger, J.A. Mouse epidermal Ia molecules have a bone marrow origin. Nature282, 321–323 (1979). ArticleCAS Google Scholar
Emile, J.F. et al. Detection of donor-derived Langerhans cells in MHC class II immunodeficient patients after allogeneic bone marrow transplantation. Br. J. Haematol.98, 480–484 (1997). ArticleCAS Google Scholar
Cook, D.N. et al. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. Immunity12, 495–503 (2000). ArticleCAS Google Scholar
Okada, T. et al. Chemokine requirements for B cell entry to lymph nodes and Peyer's patches. J. Exp. Med.196, 65–75 (2002). ArticleCAS Google Scholar
Pugh, C.W., MacPherson, G.G. & Steer, H.W. Characterization of nonlymphoid cells derived from rat peripheral lymph. J. Exp. Med.157, 1758–1779 (1983). ArticleCAS Google Scholar
Huang, F.P. et al. A discrete subpopulation of dendritic cells transports apoptotic intestinal epithelial cells to T cell areas of mesenteric lymph nodes. J. Exp. Med.191, 435–444 (2000). ArticleCAS Google Scholar
Liu, K. et al. Immune tolerance after delivery of dying cells to dendritic cells in situ. J. Exp. Med.196, 1091–1097 (2002). ArticleCAS Google Scholar
Scheinecker, C., McHugh, R., Shevach, E.M. & Germain, R.N. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med.196, 1079–1090 (2002). ArticleCAS Google Scholar
Belz, G.T. et al. The CD8α+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. J. Exp. Med.196, 1099–1104 (2002). ArticleCAS Google Scholar
Drexhage, H.A., Mullink, H., de Groot, J., Clarke, J. & Balfour, B.M. A study of cells present in peripheral lymph of pigs with special reference to a type of cell resembling the Langerhans cell. Cell Tissue Res.202, 407–430 (1979). ArticleCAS Google Scholar
Kelly, R.H., Balfour, B.M., Armstrong, J.A. & Griffiths, S. Functional anatomy of lymph nodes. II. Peripheral lymph-borne mononuclear cells. Anat. Rec.190, 5–21 (1978). ArticleCAS Google Scholar
Hemmi, H. et al. Skin antigens in the steady state are trafficked to regional lymph nodes by transforming growth factor-β1-dependent cells. Int. Immunol.13, 695–704 (2001). ArticleCAS Google Scholar
Zhang, Y. et al. APCs in the liver and spleen recruit activated allogeneic CD8+ T cells to elicit hepatic graft-versus-host disease. J. Immunol.169, 7111–7118 (2002). ArticleCAS Google Scholar
Teshima, T. et al. Acute graft-versus-host disease does not require alloantigen expression on host epithelium. Nat. Med.6, 575–581 (2002). Article Google Scholar
Vogelsang, G.B. How I treat chronic graft-versus-host disease. Blood97, 1196–1201 (2001). ArticleCAS Google Scholar
Perreault, C. et al. Persistence of host Langerhans cells following allogeneic bone marrow transplantation: possible relationship with acute graft-versus-host disease. Br. J. Haematol.60, 253–260 (1985). ArticleCAS Google Scholar
Takahashi, T. et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell76, 969–976 (1994). ArticleCAS Google Scholar
Kagi, D. et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature369, 31–37 (1994). ArticleCAS Google Scholar
Boring, L. et al. Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J. Clin. Invest.100, 2552–2561 (1997). ArticleCAS Google Scholar
Kondo, M., Weissman, I.L. & Akashi, K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell91, 661–672 (1997). ArticleCAS Google Scholar
Zeng, D., Dejbakhsh-Jones, S. & Strober, S. Granulocyte colony-stimulating factor reduces the capacity of blood mononuclear cells to induce graft-versus-host disease: impact on blood progenitor cell transplantation. Blood90, 453–463 (1997). CASPubMed Google Scholar
Cvetovic-Cvrlje, M., Roers, B.A., Waurzyniak, B., Liu, X. & Uckun, F. Targeting janus kinase 3 to attenuate the severity of acute graft versus host disease across the major histocompatibility barrier in mice. Blood98, 1607–1613 (2001). Article Google Scholar