Deficits in spatial coding and feature binding following damage to spatiotopic maps in the human pulvinar (original) (raw)

Nature Neuroscience volume 5, pages 99–100 (2002)Cite this article

Abstract

We report a patient with unilateral damage to the rostral part of the pulvinar who was impaired in localizing stimuli in the inferior visual field contralateral to the lesion and who made errors in the binding of shape and color in that quadrant. The findings demonstrate the importance of the pulvinar in spatial coding and provide support for the function of the thalamus in binding of features1. They also provide evidence for a homology between the visual field maps of the inferior and lateral subdivisions of the pulvinar in monkeys and in humans, such that the inferior visual field is represented in the rostral part of the nucleus.

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References

  1. Crick, F. Proc. Natl. Acad. Sci. USA 81, 4586–4590 (1984).
    Article CAS PubMed Google Scholar
  2. Treisman, A. Curr. Opin. Neurobiol. 6, 171–178 (1996).
    Article CAS PubMed Google Scholar
  3. Treisman, A. & Schmidt, H. Cogn. Psychol. 14, 107–141 (1982).
    Article CAS PubMed Google Scholar
  4. Cohen, A. & Ivry, R. J. Exp. Psychol. Hum. Percept. Perform. 15, 650–663 (1989).
    Article CAS PubMed Google Scholar
  5. Prinzmetal, W., Henderson, D. & Ivry, R. J. Exp. Psychol. Hum. Percept. Perform. 21, 1362–1375 (1995).
    Article CAS PubMed Google Scholar
  6. Bender, D. B. J. Neurophysiol. 46, 672–693 (1981).
    Article CAS PubMed Google Scholar
  7. Petersen, S. E., Robinson, D. L. & Keys, W. J. Neurophysiol. 54, 867–886 (1985).
    Article CAS PubMed Google Scholar
  8. Robinson, D. L. & McClurkin, J. W. in The Neurobiology of Saccadic Eye Movements (eds. Wurtz, R. H. & Goldberg, M. E.) 337–360 (Elsevier, New York, 1989).
    Google Scholar
  9. Cohen, A. & Rafal, R. D. Psychol. Sci. 2, 106–110 (1991).
    Article Google Scholar
  10. Friedman-Hill, S. R., Robertson, L. C. & Treisman, A. Science 269, 853–855 (1995).
    Article CAS Google Scholar
  11. Talairach, J. & Tournoux, P. Co-Planar Stereotaxic Atlas of the Human Brain (Thieme, New York, 1988).
    Google Scholar

Download references

Acknowledgements

This work was supported by a grant from the Medical Research Council (UK). The research was approved by the Ethics Comittees of the University of Wales, Bangor, the North West Wales NHS Trust and the Conwy–Denbighshire NHS Trust. We thank T.N. for her help in these studies.

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Authors and Affiliations

  1. Centre for Cognitive Neuroscience, University of Wales, Bangor, LL57 2AS, UK
    Robert Ward, Shai Danziger, Vanessa Owen & Robert Rafal
  2. Ben Gurion University, PO Box 653, Beer Sheva, Israel
    Shai Danziger

Authors

  1. Robert Ward
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  2. Shai Danziger
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  3. Vanessa Owen
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  4. Robert Rafal
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Correspondence toRobert Ward.

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Ward, R., Danziger, S., Owen, V. et al. Deficits in spatial coding and feature binding following damage to spatiotopic maps in the human pulvinar.Nat Neurosci 5, 99–100 (2002). https://doi.org/10.1038/nn794

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