Research Highlights (original) (raw)

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• Published: November 2002

Nature Reviews Genetics volume 3, page 822 (2002) Cite this article

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Evolution of yellow gene regulation and pigmentation in Drosophila.Wittkopp, P. J. et al. Curr. Biol. 12, 1547–1556 (2002)

One goal of evolutionary developmental biology is to understand the molecular-genetic basis of phenotypic evolution. A useful system for such studies is the evolution of the pigmentation pattern in the Drosophila lineage. By using transgenic flies that carry a heterologous yellow (melanin-encoding) gene, the authors show that changes in yellow expression in closely related species have resulted from changes in both _cis_-regulatory regions and _trans_-acting factors. The different yellow expression patterns can also be attributed to evolutionary changes in other genes.

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Research Highlights.Nat Rev Genet 3, 822 (2002). https://doi.org/10.1038/nrg940

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• Issue date: November 2002
• DOI: https://doi.org/10.1038/nrg940