Parallel processing in the mammalian retina (original) (raw)

• Casagrande, V. A. & Xu, X. in The Visual Neurosciences (eds Chalupa, L. & Werner, J. S.) 494–506 (MIT, Cambridge, 2004).
  Google Scholar
• Berson, D. M. Strange vision: ganglion cells as circadian photoreceptors. Trends Neurosci. 26, 314–320 (2003). The author reviews the recent experiments on melanopsin-containing ganglion cells, and describes their retinal distribution, their light responses, their central projections and their role in entraining the circadian clock and regulating pupil size.
  Article CAS PubMed Google Scholar
• Hendry, S. H. & Reid, C. The koniocellular pathway in primate vision. Annu. Rev. Neurosci. 23, 127–153 (2000).
  Article CAS PubMed Google Scholar
• Martin, P. R., White, A. J. R., Goodchild, A. K., Wilder, H. D. & Sefton, A. J. Evidence that blue-on cells are part of the third geniculocortical pathway in primates. Eur. J. Neurosci. 9, 1536–1541 (1997).
  Article CAS PubMed Google Scholar
• Sterling, P. in The Synaptic Organization of the Brain Vol. 4 (ed. Shepherd, G. M.) 205–253 (Oxford Univ. Press, New York, 1998).
  Google Scholar
• Boycott, B. B. & Wässle, H. Parallel processing in the mammalian retina: the Proctor Lecture. Invest. Ophthalmol. Vis. Sci. 40, 1313–1327 (1999).
  CAS PubMed Google Scholar
• Masland, R. H. The fundamental plan of the retina. Nature Neurosci. 4, 877–886 (2001).
  Article CAS PubMed Google Scholar
• He, S., Dong, W., Deng, Q., Wenig, S. & Sun, W. Seeing more clearly: recent advances in understanding retinal circuitry. Science 302, 408–411 (2003).
  Article CAS PubMed Google Scholar
• Masland, R. H. & Raviola, E. Confronting complexity: strategies for understanding the microcircuitry of the retina. Annu. Rev. Neurosci. 23, 249–284 (2000).
  Article CAS PubMed Google Scholar
• Marc, R. E. & Jones, B. W. Molecular phenotyping of retinal ganglion cells. J. Neurosci. 22, 413–427 (2002).
  Article CAS PubMed PubMed Central Google Scholar
• Nathans, J. The evolution and physiology of human color vision: insights from molecular genetic studies of visual pigments. Neuron 24, 299–312 (1999). The author describes the genes that encode the L-, M- and S-cone pigments and explains the evolution of colour vision in primates.
  Article CAS PubMed Google Scholar
• Jacobs, G. H. in Handbook of Psychology. Vol. 3 Biological Psychology (eds Gallagher, M. & Nelson, R. J.) 47–70 (Wiley, New York, 2002).
  Google Scholar
• MacNeil, M. A. & Masland, R. H. Extreme diversity among amacrine cells: implications for function. Neuron 20, 971–982 (1998).
  Article CAS PubMed Google Scholar
• Masland, R. H. Neuronal diversity in the retina. Curr. Opin. Neurobiol. 11, 431–436 (2001). The two reviews on the functional architecture of the retina by Masland (references 7 and 14) must be read by anybody interested in retinal function and vision.
  Article CAS PubMed Google Scholar
• Haverkamp, S., Grünert, U. & Wässle, H. The cone pedicle, a complex synapse in the retina. Neuron 27, 85–95 (2000). In a series of three papers (references 15, 21 and 22), Haverkamp et al . describe the molecular details and structure of the cone pedicle of the primate retina.
  Article CAS PubMed Google Scholar
• Feigenspan, A. et al. Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina. J. Neurosci. 24, 3325–3334 (2004).
  Article CAS PubMed PubMed Central Google Scholar
• Hornstein, E. P., Verweij, J. & Schnapf, J. L. Electrical coupling between red and green cones in primate retina. Nature Neurosci. 7, 745–750 (2004).
  Article CAS PubMed Google Scholar
• Li, W. & DeVries, H. Separate blue and green cone networks in the mammalian retina. Nature Neurosci. 7, 751–756 (2004).
  Article CAS PubMed Google Scholar
• O'Brien, J. J., Chen, X., MacLeish, P. R. & Massey, S. S. Connexin 36 forms gap junctions between telodendria of primate cones. Invest. Ophthalmol. Vis. Sci. 45, Assoc. Res. Vis. Ophthalmol. Meeting E Abstr. 1146 (2004).
  Google Scholar
• Lamb, T. D. & Simon, E. J. The relation between intercellular coupling and electrical noise in turtle photoreceptors. J. Physiol. (Lond.) 263, 257–286 (1976).
  Article CAS Google Scholar
• Haverkamp, S., Grünert, U. & Wässle, H. The synaptic architecture of AMPA receptors at the cone pedicle of the primate retina. J. Neurosci. 21, 2488–2500 (2001).
  Article CAS PubMed PubMed Central Google Scholar
• Haverkamp, S., Grünert, U. & Wässle, H. Localization of kainate receptors at the cone pedicles of the primate retina. J. Comp. Neurol. 436, 471–486 (2001).
  Article CAS PubMed Google Scholar
• Nomura, A. et al. Developmentally regulated postsynaptic localization of a metabotropic glutamate receptor in rat rod bipolar cells. Cell 77, 361–369 (1994).
  Article CAS PubMed Google Scholar
• Vardi, N., Duvoisin, R., Wu, G. & Sterling, P. Localization of mGluR6 to dendrites of ON bipolar cells in primate retina. J. Comp. Neurol. 423, 402–412 (2000).
  Article CAS PubMed Google Scholar
• Hering, E. Zur Lehre vom Lichtsinne IV. Über die sogenannte Intensität der Lichtempfindung und über die Empfindung des Schwarzen. Sitzungsberichte Kaiserlichen Akademie Wissenschaften Wien. Mathematisch-naturwissenschaftlicheClasse Abth. III. Bd. 69, 85–104 (1874).
  Google Scholar
• Ghosh, K. K., Bujan, S., Haverkamp, S., Feigenspan, A. & Wässle, H. Types of bipolar cells in the mouse retina. J. Comp. Neurol. 469, 70–82 (2004).
  Article PubMed Google Scholar
• MacNeil, M. A., Heussy, J. K., Dacheux, R. F., Raviola, E. & Masland, R. H. The population of bipolar cells in the rabbit retina. J. Comp. Neurol. 472, 73–86 (2004). The authors have studied the amacrine and bipolar cells of the rabbit retina and have identified most of the cell types present in that retina.
  Article PubMed Google Scholar
• Freed, M. A. Parallel cone bipolar pathways to a ganglion cell use different rates and amplitudes of quantal excitation. J. Neurosci. 20, 3956–3963 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• DeVries, S. H. Bipolar cells use kainate and AMPA receptors to filter visual information into separate channels. Neuron 28, 847–856 (2000). The author has studied signal transfer from cones to bipolar cells by double recordings from cone pedicles and bipolar cells, and has revealed important details of this first synapse of the retina.
  Article CAS PubMed Google Scholar
• Awatramani, G. B. & Slaughter, M. M. Origin of transient and sustained responses in ganglion cells of the retina. J. Neurosci. 20, 7087–7095 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• Wu, S. M., Gao, F. & Maple, B. R. Functional architecture of synapses in the inner retina: segregation of visual signals by stratification of bipolar cell axon terminals. J. Neurosci. 20, 4462–4470 (2000).
  Article CAS PubMed PubMed Central Google Scholar
• Pan, Z. -H. & Hu, H. -J. Voltage-dependent Na+ currents in mammalian retinal cone bipolar cells. J. Neurophysiol. 84, 2564–2571 (2000).
  Article CAS PubMed Google Scholar
• Kouyama, N. & Marshak, D. W. Bipolar cells specific for blue cones in the macaque retina. J. Neurosci. 12, 1233–1252 (1992).
  Article CAS PubMed PubMed Central Google Scholar
• Calkins, D. J. Seeing with S cones. Prog. Retin. Eye Res. 20, 255–287 (2001).
  Article CAS PubMed Google Scholar
• Wässle, H. & Boycott, B. B. Functional architecture of the mammalian retina. Physiol. Rev. 71, 447–480 (1991).
  Article PubMed Google Scholar
• Mollon, J. D. & Jordan, G. Eine evolutionäre Interpretation des menschlichen Farbensehens. Die Farbe 35/36, 139–170 (1988).
  Google Scholar
• Wässle, H. A patchwork of cones. Nature 397, 473–475 (1999).
  Article PubMed Google Scholar
• Jacobs, G. H., Fenwick, J. C., Calderone, J. B. & Deeb, S. S. Human cone pigment expressed in transgenic mice yields altered vision. J. Neurosci. 19, 3258–3265 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Smallwood, P. M. et al. Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision. Proc. Natl Acad. Sci. USA 100, 11706–11711 (2003).
  Article CAS PubMed PubMed Central Google Scholar
• Ingling, C. R. Jr & Martinez-Uriegas, E. The relationship between spectral sensitivity and spatial sensitivity for the primate r-g X-channel. Vision Res. 23, 1495–1500 (1983).
  Article PubMed Google Scholar
• Rodieck, R. W. in From Pigments to Perception (eds Valberg, A. & Lee, B.) 83–93 (Plenum, New York, 1991).
  Book Google Scholar
• Calkins, D. J. & Sterling, P. Evidence that circuits for spatial and color vision segregate at the first retinal synapse. Neuron 24, 313–321 (1999).
  Article CAS PubMed Google Scholar
• Haverkamp, S., Möckel, W. & Ammermüller, J. Different types of synapses with different spectral types of cones underlie color opponency in a bipolar cell of the turtle retina. Vis. Neurosci. 16, 801–809 (1999).
  CAS PubMed Google Scholar
• Berntson, A. & Taylor, W. R. Response chracteristics and receptive field widths of on-bipolar cells in the mouse retina. J. Physiol. (Lond.) 524, 879–889 (2000).
  Article CAS Google Scholar
• Euler, T. & Masland, R. H. Light-evoked responses of bipolar cells in a mammalian retina. J. Neurophysiol. 83, 1817–1829 (2000).
  Article CAS PubMed Google Scholar
• Famiglietti, E. V. & Kolb, H. A bistratified amacrine cell and synaptic circuitry in the inner plexiform layer of the retina. Brain Res. 84, 293–300 (1975).
  Article PubMed Google Scholar
• Raviola, E. & Dacheux, R. F. Excitatory dyad synapse in rabbit retina. Proc. Natl Acad. Sci. USA 84, 7324–7328 (1987).
  Article CAS PubMed PubMed Central Google Scholar
• DeVries, S. H. & Baylor, D. A. An alternative pathway for signal flow from rod photoreceptors to ganglion cells in mammalian retina. Proc. Natl Acad. Sci. USA 92, 10658–10662 (1995).
  Article CAS PubMed PubMed Central Google Scholar
• Soucy, E., Wang, Y., Nirenberg, S., Nathans, J. & Meister, M. A novel signaling pathway from rod photoreceptors to ganglion cells in mammalian retina. Neuron 21, 481–493 (1998).
  Article CAS PubMed Google Scholar
• Hack, I., Peichl, L. & Brandstätter, J. H. An alternative pathway for rod signals in the rodent retina: rod photoreceptors, cone bipolar cells, and the localization of glutamate receptors. Proc. Natl Acad. Sci. USA 96, 14130–14135 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Tsukamoto, Y., Morigiwa, K., Ueda, M. & Sterling, P. Microcircuits for night vision in mouse retina. J. Neurosci. 21, 8616–8623 (2001).
  Article CAS PubMed PubMed Central Google Scholar
• Deans, M. R., Volgyi, B., Goodenough, D. A., Bloomfield, S. A. & Paul, D. L. Connexin36 is essential for transmission of rod-mediated visual signals in the mammalian retina. Neuron 36, 703–712 (2002). The authors have studied the rod pathway in both wild-type and connexin-36-knockout mice. They showed that different RGC classes are specifically affected by the loss of gap junctions expressing connexin-36.
  Article CAS PubMed PubMed Central Google Scholar
• Kamermans, M. et al. Hemichannel-mediated inhibition in the outer retina. Science 292, 1178–1180 (2001). In recent years, Kamermans et al . have elaborated a model of horizontal cell feedback at the cone pedicle that is not based on the release of a transmitter but instead involves changes in electric potentials: shifts in the activation of Ca 2+ channels modulate glutamate release from cone pedicles.
  Article CAS PubMed Google Scholar
• Hirasawa, H. & Kaneko, A. pH changes in the invaginating synaptic cleft mediate feedback from horizontal cells to cone photoreceptors by modulating Ca2+ channels. J. Gen. Physiol. 122, 657–671 (2003).
  Article CAS PubMed PubMed Central Google Scholar
• Hombach, S. et al. Functional expression of connexin 57 in horizontal cells of the mouse retina. Eur. J. Neurosci. 19, 2633–2640 (2004).
  Article PubMed Google Scholar
• Dacey, D. M., Lee, B. B., Stafford, D. K., Pokorny, J. & Smith, V. C. Horizontal cells of the primate retina: cone specificity without spectral opponency. Science 271, 656–659 (1996).
  Article CAS PubMed Google Scholar
• Rockhill, R. L., Daly, F. J., MacNeil, M. A., Brown, S. P. & Masland, R. H. The diversity of ganglion cells in a mammalian retina. J. Neurosci. 22, 3831–3843 (2002).
  Article CAS PubMed PubMed Central Google Scholar
• Dacey, D. M., Peterson, B. B., Robinson, F. R. & Gamlin, P. D. Fireworks in the primate retina: neurotechnique in vitro photodynamics reveals diverse LGN-projecting ganglion cell types. Neuron 37, 15–27 (2003). The authors describe an exciting new technique for labelling neurons. Biotinylated rhodamine dextran is injected into the LGN, retrogradely transported and visualized by photodynamic staining.
  Article CAS PubMed Google Scholar
• Peichl, L. Alpha ganglion cells in mammalian retinae: common properties, species differences, and some comments on other ganglion cells. Vis. Neurosci. 7, 155–169 (1991).
  Article CAS PubMed Google Scholar
• Wässle, H., Boycott, B. B. & Illing, R. -B. Morphology and mosaic of on- and off-beta cells in the cat retina and some functional considerations. Proc. R. Soc. Lond. B 212, 177–195 (1981).
  Article PubMed Google Scholar
• Perry, V. H., Oehler, R. & Cowey, A. Retinal ganglion cells that project to the dorsal lateral geniculate nucleus in the macaque monkey. Neuroscience 12, 1101–1123 (1984).
  Article CAS PubMed Google Scholar
• Kolb, H. & Marshak, D. The midget pathways of the primate retina. Doc. Ophthalmol. 106, 67–81 (2003).
  Article PubMed Google Scholar
• Dacey, D. M. The mosaic of midget ganglion-cells in the human retina. J. Neurosci. 13, 5334–5355 (1993).
  Article CAS PubMed PubMed Central Google Scholar
• Vaney, D. I. Territorial organization of direction-selective ganglion-cells in rabbit retina. J. Neurosci. 14, 6301–6316 (1994).
  Article CAS PubMed PubMed Central Google Scholar
• Dacey, D. M. Monoamine-accumulating ganglion-cell type of the cat's retina. J. Comp. Neurol. 288, 59–80 (1989).
  Article CAS PubMed Google Scholar
• Buhl, E. H. & Peichl, L. Morphology of rabbit retinal ganglion-cells projecting to the medial terminal nucleus of the accessory optic-system. J. Comp. Neurol. 253, 163–174 (1986).
  Article CAS PubMed Google Scholar
• Isayama, T., Berson, D. M. & Pu, M. Theta ganglion cell type of cat retina. J. Comp. Neurol. 417, 32–48 (2000). Berson and colleagues have investigated the morphological and physiological classes and the central projections of cat RGCs in a series of careful papers. Their classification scheme of RGCs in the cat is the most advanced description of RGCs in any retina.
  Article CAS PubMed Google Scholar
• Kuffler, S. W. Discharge patterns and functional organization of mammalian retina. J. Neurophysiol. 16, 37–68 (1953).
  Article CAS PubMed Google Scholar
• Enroth-Cugell, C. & Robson, J. C. The contrast sensitivity of retinal ganglion cells of the cat. J. Physiol. (Lond.) 187, 517–552 (1966). This classic paper has established parallel processing in the mammalian retina by showing that cat RGCs can be subdivided into those with linear summation of light stimuli (X-cells) and those with nonlinear summation (Y-cells).
  Article CAS Google Scholar
• Boycott, B. B. & Wässle, H. The morphological types of ganglion cells of the domestic cat's retina. J. Physiol. (Lond.) 240, 397–419 (1974).
  Article CAS PubMed Central Google Scholar
• Levick, W. R. Receptive fields of cat retinal ganglion cells with special reference to the alpha cells. Prog. Retin. Eye Res. 15, 457–500 (1996).
  Article Google Scholar
• Dacey, D. M. & Packer, O. S. Colour coding in the primate retina: diverse cell types and cone-specific circuitry. Curr. Opin. Neurobiol. 13, 421–427 (2003). A review of the retinal circuits that are involved in the segregation of L- versus M-signals and with blue–yellow oppenency.
  Article CAS PubMed Google Scholar
• Demb, J. B., Haarsma, L., Freed, M. A. & Sterling, P. Functional circuitry of the retinal ganglion cell's nonlinear receptive field. J. Neurosci. 19, 9756–9767 (1999).
  Article CAS PubMed PubMed Central Google Scholar
• Berry, M. J. II, Brivanlou, I. H., Jordan, T. A. & Meister, M. Anticipation of moving stimuli by the retina. Nature 398, 334–338 (1999).
  Article CAS PubMed Google Scholar
• Demb, J. B., Zaghloul, K. & Sterling, P. Cellular basis for the response to second-order motion cues in Y retinal ganglion cells. Neuron 32, 711–721 (2001).
  Article CAS PubMed Google Scholar
• Demb, J. B., Zaghloul, K., Haarsma, L. & Sterling, P. Bipolar cells contribute to nonlinear spatial summation in the brisk-transient (Y) ganglion cell in mammalian retina. J. Neurosci. 21, 7447–7454 (2001). In a series of excellent papers, Demb and colleagues have investigated the functional circuitry of brisk transient (Y) cells of the mammalian retina.
  Article CAS PubMed PubMed Central Google Scholar
• Ölveczky, B. P., Baccus, S. A. & Meister, M. Segregation of object and background motion in the retina. Nature 423, 401–408 (2003).
  Article CAS PubMed Google Scholar
• Brown, S. P. & Masland, R. H. Spatial scale and cellular substrate of contrast adaptation by retinal ganglion cells. Nature Neurosci. 4, 44–51 (2001).
  Article CAS PubMed Google Scholar
• Baccus, S. A. & Meister, M. Retina versus cortex: contrast adaptation in parallel visual pathways. Neuron 42, 5–7 (2004).
  Article CAS PubMed Google Scholar
• Freed, M. A. Rate of quantal excitation to a retinal ganglion cell evoked by sensory input. J. Neurophysiol. 83, 2956–2966 (2000).
  Article CAS PubMed Google Scholar
• Freed, M. A., Smith, R. G. & Sterling, P. Timing of quantal release from the retinal bipolar terminal is regulated by a feedback circuit. Neuron 38, 89–101 (2003). In a series of careful experiments the authors studied the signal transfer from cone bipolar cells onto RGCs.
  Article CAS PubMed Google Scholar
• Chiao, C. -C. & Masland, R. H. Contextual tuning of direction-selective retinal ganglion cells. Nature Neurosci. 6, 1251–1252 (2003).
  Article CAS PubMed Google Scholar
• Barlow, H. B. & Levick, W. R. The mechanism of directionally selective units in rabbit's retina. J. Physiol (Lond.) 178, 477–504 (1965).
  Article CAS Google Scholar
• Taylor, W. R., He, S., Levick, W. R. & Vaney, D. I. Dendritic computation of direction selectivity by retinal ganglion cells. Science 289, 2347–2350 (2000).
  Article CAS PubMed Google Scholar
• Borg-Graham, L. J. The computation of directional selectivity in the retina occurs presynaptic to the ganglion cell. Nature Neurosci. 4, 176–183 (2001).
  Article CAS PubMed Google Scholar
• Fried, S. I., Münch, T. A. & Werblin, F. S. Mechanisms and circuitry underlying directional selectivity in the retina. Nature 420, 411–414 (2002). The authors recorded direction-selective ganglion cells and studied their synaptic inputs. They describe different connectivities for the preferred and the null direction.
  Article CAS PubMed Google Scholar
• Yoshida, K. et al. A key role of starburst amacrine cells in originating retinal directional selectivity and optokinetic eye movement. Neuron 30, 771–780 (2001). In an elegant experiment, using transgenic mouse technology, the authors were able to knock out cholinergic (starburst) amacrine cells and to show that directional selectivity was abolished. This strongly indicates that cholinergic amacrine cells are a vital participant in directional selectivity.
  Article CAS PubMed Google Scholar
• Euler, T., Detwiler, P. B. & Denk, W. Directionally selective calcium signals in dendrites of starburst amacrine cells. Nature 418, 845–852 (2002). By the application of two-photon microscopy and calcium-imaging, the authors showed that cholinergic amacrine cells (starburst cells) have directionally selective light responses.
  Article CAS PubMed Google Scholar
• Münch, T. A., Fried, S. I. & Werblin, F. S. Starburst cells initiate directional selective responses in rabbit retina. Invest. Ophthalmol. Vis. Sci. 43 (Suppl. 2), 2981 (2002).
  Google Scholar
• Taylor, W. R. & Vaney, D. I. Diverse synaptic mechanisms generate direction selectivity in the rabbit retina. J. Neurosci. 22, 7712–7720 (2002).
  Article CAS PubMed PubMed Central Google Scholar
• Taylor, W. R. & Vaney, D. I. New directions in retinal research. Trends Neurosci. 26, 379–385 (2003). The most recent and comprehensive review of the mechanisms underlying direction selectivity. Both the presynaptic and the postsynaptic mechanisms, as well as evidence for and against them, are discussed.
  Article CAS PubMed Google Scholar
• Martin, P. R. Colour processing in the primate retina: recent progress. J. Physiol. (Lond.) 513, 631–638 (1998).
  Article CAS Google Scholar
• Martin, P. R., Lee, B. B., White, A. J. R., Solomon, S. G. & Rüttiger, L. Chromatic sensitivity of ganglion cells in the peripheral primate retina. Nature 410, 933–935 (2001).
  Article CAS PubMed Google Scholar
• Diller, L. et al. L and M cone contributions to the midget and parasol ganglion cell receptive fields of macaque monkey retina. J. Neurosci. 24, 1079–1088 (2004).
  Article CAS PubMed PubMed Central Google Scholar
• Mullen, K. T. & Kingdom, F. A. A. Differential distributions of red-green and blue-yellow cone opponency across the visual field. Vis. Neurosci. 19, 109–118 (2002).
  Article PubMed Google Scholar
• Dacey, D. M. & Lee, B. B. The blue-on opponent pathway in primate retina originates from a distinct bistratified ganglion-cell type. Nature 367, 731–735 (1994).
  Article CAS PubMed Google Scholar
• Dacey, D. M., Peterson, B. B. & Robinson, F. R. Identification of an S-cone opponent OFF pathway in the macaque monkey retina: morphology, physiology and possible circuitry. Invest. Ophthalmol. Vis. Sci. 43 (Suppl. 2), 2983 (2002).
  Google Scholar
• Peterson, B. B. et al. Functional architecture of the photoreceptive ganglion cells in the primate retina: morphology, mosaic organization and central targets of melanopsin immunostained cells. Invest. Ophthalmol. Vis. Sci. 44, Assoc. Res. Vis. Ophthalmol. Meeting E-Abstr. 5182 (2003).
  Article Google Scholar
• Barlow, H. B. & Levick, W. R. Changes in the maintained discharge with adaptation level in the cat retina. J. Physiol. (Lond.) 202, 699–718 (1969).
  Article CAS Google Scholar
• Roska, B. & Werblin, F. Vertical interactions across ten parallel, stacked representations in the mammalian retina. Nature 410, 583–587 (2001). The authors studied light responses of the different RGC classes in the rabbit retina and correlated them with the stratification level of RGC dendrites within the IPL.
  Article CAS PubMed Google Scholar
• Werblin, F. S. & Roska, B. M. Parallel visual processing: a tutorial of retinal function. Int. J. Bifurc. Chaos 14, 843–852 (2004).
  Article Google Scholar
• Haverkamp, S. & Wässle, H. Immunocytochemical analysis of the mouse retina. J. Comp. Neurol. 424, 1–23 (2000).
  Article CAS PubMed Google Scholar
• Brandstätter, J. H., Greferath, U., Euler, T. & Wässle, H. Co-stratification of GABAA receptors with the directionally selective circuitry of the rat retina. Vis. Neurosci. 12, 345–358 (1995).
  Article PubMed Google Scholar
• Brown, S. P. & Masland, R. H. Costratification of a population of bipolar cells with the direction-selective circuitry of the rabbit retina. J. Comp. Neurol. 408, 97–106 (1999).
  Article CAS PubMed Google Scholar
• Vaney, D. I. Retinal neurons: cell types and coupled networks. Perspect. Analyt. Philos. 136, 239–254 (2002).
  Google Scholar
• Menger, N., Pow, D. V. & Wässle, H. Glycinergic amacrine cells of the rat retina. J. Comp. Neurol. 401, 34–46 (1998).
  Article CAS PubMed Google Scholar
• Strettoi, E., Porciatti, V., Falsini, B., Pignatelli, V. & Rossi, C. Morphological and functional abnormalities in the inner retina of the rd/rd mouse. J. Neurosci. 22, 5492–5504 (2002).
  Article CAS PubMed PubMed Central Google Scholar
• Marc, R. E., Jones, B. W., Watt, C. B. & Strettoi, E. Neural remodeling in retinal degeneration. Prog. Retin. Eye Res. 22, 607–655 (2003). This is an excellent review of the changes in the mammalian retina that are triggered by degeneration of the photoreceptors.
  Article PubMed Google Scholar
• Marc, R. E. & Jones, B. W. Retinal remodeling in inherited photoreceptor degenerations. Mol. Neurobiol. 28, 139–147 (2003).
  Article CAS PubMed Google Scholar
• Loewenstein, J. I., Montezuma, S. R. & Rizzo, J. F. 3rd. Outer retinal degeneration. Arch. Ophthalmol. 122, 587–596 (2004).
  Article PubMed Google Scholar
• Surace, E. M. & Auricchio, A. Adeno-associated viral vectors for retinal gene transfer. Prog. Retin. Eye Res. 22, 705–719 (2003).
  Article CAS PubMed Google Scholar
• Meister, M. Multineuronal codes in retinal signaling. Proc. Natl Acad. Sci. USA 93, 609–614 (1996).
  Article CAS PubMed PubMed Central Google Scholar
• Berry, M. J., Warland, D. K. & Meister, M. The structure and precision of retinal spike trains. Proc. Natl Acad. Sci. USA 94, 5411–5416 (1997).
  Article CAS PubMed PubMed Central Google Scholar
• Meister, M. & Berry, M. J. The neural code of the retina. Neuron 22, 435–450 (1999). One of several recently published papers describing how RGCs react to specific aspects of complex light stimuli and how they adapt to natural stimuli. Their studies are excellent examples of the application of multielectrode recordings for the study of neuronal assemblies.
  Article CAS PubMed Google Scholar
• Nirenberg, S. & Latham, P. E. Population coding in the retina. Curr. Opin. Neurobiol. 8, 488–493 (1998).
  Article CAS PubMed Google Scholar
• Nirenberg, S. & Latham, P. E. Decoding neuronal spike trains: how important are correlations? Proc. Natl Acad. Sci. USA 100, 7348–7353 (2003). The authors address the question of whether the correlated firing of neighbouring RGCs transfers more information to the brain than uncorrelated signals.
  Article CAS PubMed PubMed Central Google Scholar
• Chichilnisky, E. J. & Kalmar, R. S. Temporal resolution of ensemble visual motion signals in primate retina. J. Neurosci. 23, 6681–6689 (2003).
  Article CAS PubMed PubMed Central Google Scholar
• Boos, R., Schneider, H. & Wässle, H. Voltage-gated and transmitter-gated currents of AII-amacrine cells in a slice preparation of the rat retina. J. Neurosci. 13, 2874–2888 (1993).
  Article CAS PubMed PubMed Central Google Scholar
• Flores-Herr, N., Protti, D. A. & Wässle, H. Synaptic currents generating the inhibitory surround of ganglion cells in the mammalian retina. J. Neurosci. 21, 4852–4863 (2001).
  Article CAS PubMed PubMed Central Google Scholar
• McMahon, M. J., Packer, O. S. & Dacey, D. M. The classical receptive field surround of primate parasol ganglion cells is mediated primarely by a non-GABAergic pathway. J. Neurosci. 24, 3736–3745 (2004).
  Article CAS PubMed PubMed Central Google Scholar
• Rodieck, R. W. The First Steps in Seeing (Sinauer Ass. Inc., Sunderland, Massachusetts, 1998).
  Google Scholar
• Witkovsky, P. Dopamine and retinal function. Doc. Ophthalmol. 108, 17–40 (2004).
  Article PubMed Google Scholar
• Demb, J. B. & Pugh, E. N. Jr. Connexin36 forms synapses essential for night vision. Neuron 36, 551–553 (2002).
  Article CAS PubMed Google Scholar
• Feng, G. et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 28, 41–51 (2000).
  Article CAS PubMed Google Scholar
• Sun, W., Li, N. & He, S. Large-scale morphological survey of mouse retinal ganglion cells. J. Comp. Neurol. 451, 115–126 (2002).
  Article PubMed Google Scholar
• Wässle, H. Die Netzhaut ein Gehirn im Auge. Jahrbuch 2001 Deutschen Akademie Naturforscher Leopoldina 47, 493–506 (2002).
  Google Scholar
• Fried, S. I., Münch, T. A. & Werblin, F. S. The circuitry underlying directional excitation and inhibition to DS cells. Invest. Ophthalmol. Vis. Sci. 45, Assoc. Res. Vis. Ophthalmol. Meeting E-Abstr. 2266 (2004).
  Google Scholar