Suppressed miR-424 expression via upregulation of target gene Chk1 contributes to the progression of cervical cancer (original) (raw)
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM . Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893–2917. ArticleCAS Google Scholar
Lee RC, Feinbaum RL, Ambros V . The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993; 75: 843–854. ArticleCAS Google Scholar
Pillai RS, Bhattacharyya SN, Filipowicz W . Repression of protein synthesis by miRNAs: how many mechanisms? Trends Cell Biol 2007; 17: 118–126. ArticleCAS Google Scholar
Bartel DP . MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215–233. ArticleCAS Google Scholar
Garzon R, Calin GA, Croce CM . MicroRNAs in Cancer. Annu Rev Med 2009; 60: 167–179. ArticleCAS Google Scholar
Kent OA, Mendell JT . A small piece in the cancer puzzle: microRNAs as tumor suppressors and oncogenes. Oncogene 2006; 25: 6188–6196. ArticleCAS Google Scholar
Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH . Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 2008; 283: 1026–1033. ArticleCAS Google Scholar
Selcuklu SD, Donoghue MT, Spillane C . miR-21 as a key regulator of oncogenic processes. Biochem Soc Trans 2009; 37 (Part 4): 918–925. ArticleCAS Google Scholar
Medina PP, Nolde M, Slack FJ . OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 2010; 467: 86–90. ArticleCAS Google Scholar
Yan LX, Huang XF, Shao Q, Huang MY, Deng L, Wu QL et al. MicroRNA miR-21 overexpression in human breast cancer is associated with advanced clinical stage, lymph node metastasis and patient poor prognosis. RNA 2008; 14: 2348–2360. ArticleCAS Google Scholar
Li Y, Wang F, Xu J, Ye F, Shen Y, Zhou J et al. Progressive miRNA expression profiles in cervical carcinogenesis and identification of HPV-related target genes for miR-29. J Pathol 2011; 224: 484–495. ArticleCAS Google Scholar
Rosa A, Ballarino M, Sorrentino A, Sthandier O, De Angelis FG, Marchioni M et al. The interplay between the master transcription factor PU.1 and miR-424 regulates human monocyte/macrophage differentiation. Proc Natl Acad Sci USA 2007; 104: 19849–19854. ArticleCAS Google Scholar
Sarkar S, Dey BK, Dutta A . MiR-322/424 and -503 are induced during muscle differentiation and promote cell cycle quiescence and differentiation by down-regulation of Cdc25A. Mol Biol Cell 2010; 21: 2138–2149. ArticleCAS Google Scholar
Ghosh G, Subramanian IV, Adhikari N, Zhang X, Joshi HP, Basi D et al. Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-alpha isoforms and promotes angiogenesis. J Clin Invest 2010; 120: 4141–4154. ArticleCAS Google Scholar
Liu Q, Fu H, Sun F, Zhang H, Tie Y, Zhu J et al. miR-16 family induces cell cycle arrest by regulating multiple cell cycle genes. Nucleic Acids Res 2008; 36: 5391–5404. ArticleCAS Google Scholar
Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R et al. miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood 2009; 114: 3255–3264. ArticleCAS Google Scholar
Imig J, Motsch N, Zhu JY, Barth S, Okoniewski M, Reineke T et al. microRNA profiling in Epstein-Barr virus-associated B-cell lymphoma. Nucleic Acids Res 2011; 39: 1880–1893. ArticleCAS Google Scholar
Chen ZL, Zhao XH, Wang JW, Li BZ, Wang Z, Sun J et al. microRNA-92a promotes lymph node metastasis of human esophageal squamous cell carcinoma via E-cadherin. J Biol Chem 2011; 286: 10725–10734. ArticleCAS Google Scholar
Li J, Huang H, Sun L, Yang M, Pan C, Chen W et al. MiR-21 indicates poor prognosis in tongue squamous cell carcinomas as an apoptosis inhibitor. Clin Cancer Res 2009; 15: 3998–4008. ArticleCAS Google Scholar
Wang X, Tang S, Le SY, Lu R, Rader JS, Meyers C et al. Aberrant expression of oncogenic and tumor-suppressive microRNAs in cervical cancer is required for cancer cell growth. PLoS One 2008; 3: e2557. Article Google Scholar
Witten D, Tibshirani R, Gu SG, Fire A, Lui WO . Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. BMC Biol 2010; 8: 58. Article Google Scholar
Cole KA, Huggins J, Laquaglia M, Hulderman CE, Russell MR, Bosse K et al. RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma. Proc Natl Acad Sci USA 2011; 108: 3336–3341. ArticleCAS Google Scholar
Deryugina EI, Quigley JP . Matrix metalloproteinases and tumor metastasis. Cancer Metastasis Rev 2006; 25: 9–34. ArticleCAS Google Scholar
Yu W, Liu J, Xiong X, Ai Y, Wang H . Expression of MMP9 and CD147 in invasive squamous cell carcinoma of the uterine cervix and their implication. Pathol Res Pract 2009; 205: 709–715. ArticleCAS Google Scholar
Lin LF, Chuang CH, Li CF, Liao CC, Cheng CP, Cheng TL et al. ZBRK1 acts as a metastatic suppressor by directly regulating MMP9 in cervical cancer. Cancer Res 2010; 70: 192–201. ArticleCAS Google Scholar
Forrest AR, Kanamori-Katayama M, Tomaru Y, Lassmann T, Ninomiya N, Takahashi Y et al. Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. Leukemia 2010; 24: 460–466. ArticleCAS Google Scholar
Kawahigashi Y, Mishima T, Mizuguchi Y, Arima Y, Yokomuro S, Kanda T et al. MicroRNA profiling of human intrahepatic cholangiocarcinoma cell lines reveals biliary epithelial cell-specific microRNAs. J Nihon Med Sch 2009; 76: 188–197. ArticleCAS Google Scholar
Rentoft M, Fahlen J, Coates PJ, Laurell G, Sjostrom B, Ryden P et al. miRNA analysis of formalin-fixed squamous cell carcinomas of the tongue is affected by age of the samples. Int J Oncol 2011; 38: 61–69. CASPubMed Google Scholar
Wang YX, Zhang XY, Zhang BF, Yang CQ, Chen XM, Gao HJ . Initial study of microRNA expression profiles of colonic cancer without lymph node metastasis. J Dig Dis 2010; 11: 50–54. Article Google Scholar
Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T . Identification of novel genes coding for small expressed RNAs. Science 2001; 294: 853–858. ArticleCAS Google Scholar
Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A, Enright AJ . miRBase: microRNA sequences, targets and gene nomenclature. Nucleic Acids Res 2006; 34 (Database issue): D140–D144. ArticleCAS Google Scholar
Wang Z, Wang M, Kar S, Carr BI . Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition. J Cell Physiol 2009; 221: 213–220. ArticleCAS Google Scholar
Lopez-Girona A, Tanaka K, Chen XB, Baber BA, McGowan CH, Russell P . Serine-345 is required for Rad3-dependent phosphorylation and function of checkpoint kinase Chk1 in fission yeast. Proc Natl Acad Sci USA 2001; 98: 11289–11294. ArticleCAS Google Scholar
Bartek J, Lukas J . Mammalian G1- and S-phase checkpoints in response to DNA damage. Curr Opin Cell Biol 2001; 13: 738–747. ArticleCAS Google Scholar
Zhao H, Watkins JL, Piwnica-Worms H . Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc Natl Acad Sci USA 2002; 99: 14795–14800. ArticleCAS Google Scholar
Zachos G, Rainey MD, Gillespie DA . Chk1-deficient tumour cells are viable but exhibit multiple checkpoint and survival defects. EMBO J 2003; 22: 713–723. ArticleCAS Google Scholar
Madoz-Gurpide J, Canamero M, Sanchez L, Solano J, Alfonso P, Casal JI . A proteomics analysis of cell signaling alterations in colorectal cancer. Mol Cell Proteomics 2007; 6: 2150–2164. ArticleCAS Google Scholar
Verlinden L, Vanden Bempt I, Eelen G, Drijkoningen M, Verlinden I, Marchal K et al. The E2F-regulated gene Chk1 is highly expressed in triple-negative estrogen receptor /progesterone receptor /HER-2 breast carcinomas. Cancer Res 2007; 67: 6574–6581. ArticleCAS Google Scholar
Ehlen O, Nodin B, Rexhepaj E, Brandstedt J, Uhlen M, Alvarado-Kristensson M et al. RBM3-regulated genes promote DNA integrity and affect clinical outcome in epithelial ovarian cancer. Transl Oncol 2011; 4: 212–221. Article Google Scholar
Gao Q, Huang X, Tang D, Cao Y, Chen G, Lu Y et al. Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells. Apoptosis 2006; 11: 1789–1800. ArticleCAS Google Scholar
Li YL, Ye F, Hu Y, Lu WG, Xie X . Identification of suitable reference genes for gene expression studies of human serous ovarian cancer by real-time polymerase chain reaction. Anal Biochem 2009; 394: 110–116. ArticleCAS Google Scholar
Shen Y, Li Y, Ye F, Wang F, Lu W, Xie X . Identification of suitable reference genes for measurement of gene expression in human cervical tissues. Anal Biochem 2010; 405: 224–229. ArticleCAS Google Scholar
Li YL, Ye F, Cheng XD, Hu Y, Zhou CY, Lu WG et al. Identification of glia maturation factor beta as an independent prognostic predictor for serous ovarian cancer. Eur J Cancer 2010; 46: 2104–2118. ArticleCAS Google Scholar
Ye F, Hu Y, Lu W, Zhou C, Xie X . Expression of leukaemia inhibitory factor in epithelial ovarian carcinoma: correlation with clinical characteristics. Histopathology 2008; 53: 224–228. ArticleCAS Google Scholar