Abnormal expression and function of the E-cadherin–catenin complex in gastric carcinoma cell lines (original) (raw)

References

• Becker, K. F., Atkinson, M. J., Reich, U., Huang, H. H., Nekarda, H., Siewert, B. R. & Hofler, H. (1993). Exon skipping in the E-cadherin gene transcript in metastatic human gastric carcinomas. Hum Mol Genet 2: 803–804.
  Article CAS Google Scholar
• Becker, K. F., Atkinson, M. J., Reich, U., Becker, I., Nekarda, H., Siewert, J. R. & Hofler, H. (1994). E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res 54: 3845–3852.
  CAS PubMed Google Scholar
• Behrens, J., von Kreis, J. P., Kuhl, M., Bruhn, L., Wedlich, D., Grosschedl, R. & Birchmeier, W. (1996). Functional interaction of β-catenin with the transcription factor LEF-1. Nature 382: 638
  Article CAS Google Scholar
• Bergerheim, U. S. R., Kunimi, K., Collins, B. P. & Ekman, P. (1991). Deletion mapping of chromosomes 8, 10 and 16 in prostate carcinoma. Genes Chrom Cancer 3: 215–220.
  Article CAS Google Scholar
• Birchmeier, W., Michael Weidner, K. & Behrens, J. (1993). Molecular mechanisms leading to loss of differentiation and gain of invasiveness in epithelial cells. J Cell Sci 17: 159–164.
  Article CAS Google Scholar
• Bringuier, P. P., Umbas, R., Schaafsma, H. E., Karthaus, H. F., Debruyne, F. M. & Schalken, J. A. (1993). Decreased E-cadherin immunoreactivity correlates with poor survival in patients with bladder tumours. Cancer Res 53: 3241–3245.
  CAS PubMed Google Scholar
• Carter, B. S., Ewing, C. M., Ward, W. S., Treiger, B. F., Aalders, T. W., Schalken, J. A., Epstein, J. I. & Issac, W. B. (1991). Allelic loss of chromosomes 16q and 10q in human prostate cancer. Proc Natl Acad Sci USA 87: 8751–8755.
  Article Google Scholar
• Downing, J. R. & Reynolds, A. B. (1991). PDGF, CSF-1, and EGF induce tyrosine phosporylation of p120, a pp60src transformation associated substrate. Oncogene 6: 607–613.
  CAS PubMed Google Scholar
• Efstathiou, J. A., Noda, M., Rowan, A., Dixon, C., Chinery, R., Jawhari, A., Hattori, T., Wright, N. A., Bodmer, W. & Pignatlli, M. (1998). Intestinal trefoil factor controls the expression of the adenomatous polyposis coli-catenin and the E-cadherin–catenin complexes in human colon carcinoma cells. Proc Natl Acad Sci USA 95: 3122–3127.
  Article CAS Google Scholar
• Frixen, U. H., Behrens, J., Sachs, M., Eberle, G., Voss, B., Warda, A., Locner, D. & Birchmeier, W. (1991). E-cadherin-mediated cell–cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 113: 173–185.
  Article CAS Google Scholar
• Geiger, B., Tokuyasu, K. T., Dutton, A. H. & Singer, S. J. (1980). Vinculin, an intracellular protein localized at specialized sites where microfilament bundles terminate at cell membranes. Proc Nat Acad Sci USA 7777: 4127–4131.
  Article Google Scholar
• Guilford, P., Hopkin, J., Harraway, J., McLeod, M., McLeod, N., Harawira, P., Taite, H., Scoular, R., Miller, A. & Reeve, A. E. (1998). E-cadherin germline mutations in familial gastric carcinoma. Nature 392: 402–404.
  Article CAS Google Scholar
• Gumbiner, B. (1995). Signal transduction by β-catenin. Curr Opin Cell Biol 7: 634–640.
  Article CAS Google Scholar
• Hirano, S., Kimoto, N., Shimoyama, Y., Hirohashi, S. & Takeichi, M. (1992). Identification of a neural α-catenin as a key regulator of cadherin function and multicellular organization. Cell 70: 293–301.
  Article CAS Google Scholar
• Horii, A., Nakatsuru, S., Miyoshi, Y., Ichii, S., Nagase, H., Kato, Y., Yanagisawa, A. & Nakamura, Y. (1992). The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer. Cancer Res 52: 3231–3233.
  CAS PubMed Google Scholar
• Hoschuetzky, H., Aberle, H. & Kemler, R. (1994). β-catenin mediates the interaction of the cadherin–catenin complex with epidermal growth factor receptor. J Cell Biol 127: 1375–1380.
  Article CAS Google Scholar
• Jawhari, A., Poole, S., Jordan, S., Browne, P., Pignatelli, M. & Farthing, M. J. G. (1997). Abnormal immunoreactivity of the E-cadherin–catenin complex in gastric carcinoma: relationship with patient survival. Gastroenterology 112: 46–54.
  Article CAS Google Scholar
• Kawanishi, J., Kato, J., Sasaki, K., Fujii, S., Watanabe, N. & Niitsu, Y. (1995). Loss of E-cadherin-dependent cell–cell adhesion due to mutation of the β-catenin gene in a human cancer cell line, HSC-39. Mol Cell Biol 15: 1175–1181.
  Article CAS Google Scholar
• Korinek, V., Barker, N., Morin, P. J., van Wichen, D., de Weger, R., Kinzler, K. W., Vogelstein, B. & Clevers, H. (1997). Constitutive transcriptional activation by a β-catenin–Tcf complex in APC−/−colon carcinoma. Science 275: 1784–1787.
  Article CAS Google Scholar
• Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680–685.
  Article CAS Google Scholar
• Lemoine, N. R., Jain, S., Silvestre, F., Lopes, C., Hughes, C. M., McLelland, E., Gullick, W. J. & Filipe, M. I. (1991). Amplification and over-expression of the EGF receptor and c-erbB-2 proto-oncogenes in human stromach cancer. Br J Cancer 64: 79–83.
  Article CAS Google Scholar
• Matsuura, K., Kawanishi, J., Fujii, S., Imamura, M., Hirano, S., Takeichi, M. & Niitsu, Y. (1992). Altered expression of E-cadherin in gastric cancer tissues and carcinomatous fluid. Br J Cancer 66: 1122–1130.
  Article CAS Google Scholar
• Munemitsu, S., Albert, I., Souza, B., Rubinfeld, B. & Polakis, P. (1995). Regulation of intracellular β-catenin levels by the adenomatous polyposis coli (APC) tumour-suppressor protein. Proc Natl Acad Sci USA 92: 3046–3050.
  Article CAS Google Scholar
• Nagafuchi, A. & Takeichi, M. (1988). Cell-binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO J 7: 3679–3684.
  Article CAS Google Scholar
• Nagafuchi, A. & Takeichi, M. (1989). Transmembrane control of cadherin-mediated cell adhesion: a 94 kD protein functionally associated with a specific region of the cytoplasmic domain of E-cadherin. Cell Regul 1: 37–44.
  Article CAS Google Scholar
• Nigam, A. K., Savage, F. J., Boulos, P. B., Stamp, G. W., Liu, D. & Pignatelli, M. (1993). Loss of cell–cell and cell–matrix adhesion molecules in colorectal cancern. Br J Cancer 68: 507–514.
  Article CAS Google Scholar
• Ochiai, A., Akimoto, S., Kanai, Y., Shibata, T., Oyama, T. & Hirohashi, S. (1994). c-erbB-2 gene product associates with catenins in human cancer cells. Biochem Biophys Res Commun 205: 73–78.
  Article CAS Google Scholar
• Oda, T., Kanai, Y., Oyama, T., Yoshiura, K., Shimoyama, Y., Birchmeier, W., Sugimura, T. & Hirohashi, S. (1994). E-cadherin gene mutations in human gastric carcinoma cell lines. Proc Natl Acad Sci USA 91: 1958–1962.
  Article Google Scholar
• Oka, H., Shiozaki, H., Kobayashi, K., Inoue, M., Tahara, H., Kobayashi, T., Takatsuka, Y., Matsuyoshi, N., Hirano, S. & Takeichi, M. (1993). Expression of E-cadherin cell adhesion molecules in human breast cancer tissues and its relationship to metastasis. Cancer Res 53: 1696–1701.
  CAS PubMed Google Scholar
• Ozawa, M. & Kemler, R. (1992). Molecular organization of the uvomorulin–catenin complex. J Cell Biol 116: 989–996.
  Article CAS Google Scholar
• Peifer, M. (1995). Cell adhesion and signal transduction: the armadillo connection. Trend Cell Biol 5: 224–229.
  Article CAS Google Scholar
• Pignatelli, M., Ansari, T. W., Gunter, P., Liu, D., Hirano, S., Takeichi, M., Kloppel, G. & Lemoine, N. R. (1994). Loss of membranous E-cadherin expression in pancreatic cancer: correlation with lymph node metastasis, high grade and advanced stage. J Pathol 174: 243–248.
  Article CAS Google Scholar
• Rubinfeld, B., Souza, B., Albert, I., Muller, O., Chamberlain, S. H., Masiarz, F. R., Munemitsu, S. & Paulakis, P. (1993). Association of the APC gene product with β-catenin. Science 262: 1731–1734.
  Article CAS Google Scholar
• Sato, T., Tanigami, A., Yamakawa, K., Akiyama, F., Dasumi, F., Sakamato, G. & Nakamura, Y. (1990). Allotype of breast cancer: cumulative allele losses promote tumor progression in primary breast cancer. Cancer Res 50: 7184–7189.
  CAS PubMed Google Scholar
• Shapiro, L., Fannon, A. M., Kwong, P. D., Thompson, A., Lehmann, M. L., Grubel, G., Legrand, J. F., Als-Nielson, J., Coleman, K. R. & Hendrickson, W. A. (1995). Structural basis of cell-cell adhesion by cadherins. Nature 374: 327–386.
  Article CAS Google Scholar
• Shibamoto, S., Haykawa, M., Takeuchi, K., Hori, T., Oku, N., Miyazazwa, K., Kitamura, N., Takeichi, M. & Ito, F. (1994). Tyrosine phosphorylation of β-catenin and plakoglobin enhanced by hepatocyte growth factor and epidermal growth factor in human carcinoma cells. Cell Adhes Commun 1: 295–305.
  Article CAS Google Scholar
• Shimoyama, Y. & Hirohashi, S. (1991). Expression of E- and P-cadherin in gastric carcinomas. Cancer Res 51: 2185–2192.
  CAS PubMed Google Scholar
• Shiozaki, H., Tahara, H., Oka, H., Miyata, M., Kobayashi, K., Tamura, S., Iihara, K., Doki Y Hirano, S. & Takeichi, M. et al (1991). Expression of immunoreactive E-cadherin adhesion moleules in human cancers. Am J Pathol 139: 17–23.
  CAS PubMed PubMed Central Google Scholar
• Shiozaki, H., Lihara, K., Oka, H., Kadowaki, T., Matsui, S., Gofuku, J., Inoue, M., Nagafuchi, A., Tsukita, S. & Mori, T. (1994). Immunohistochemical detection of α-catenin expression in human cancers. Am J Pathol 144: 667–674.
  CAS PubMed PubMed Central Google Scholar
• Sparks, A. B., Morin, P. J., Vogelstein, B. & Kinzler, K. W. (1998). Mutational analysis of the APC/β-catenin pathway in colorectal cancer. Cancer Res 58: 1130–1134.
  CAS PubMed Google Scholar
• Staddon, J., Smales, C., Schulze, C., Esch, F. S. & Rubin, L. L. (1995). p120, a p120-related protein (p100), and the cadherin/catenin complex. J Cell Biol 130: 369–381.
  Article CAS Google Scholar
• St Croix, B., Sheehan, C., Rak, J. W., Florenes, V. A., Slingerland, J. M. & Kerbel, R. S. (1998). E-cadherin dependent growth suppression is mediated by the cyclin-dependent kinase inhibitor p27KIP1. J Cell Biol 142: 557–571.
  Article CAS Google Scholar
• Su, L. K., Vogelstein, B. & Kinzler, K. W. (1993). Association of the APC tumour suppressor protein with catenins. Science 262: 1734–1737.
  Article CAS Google Scholar
• Tahara, E. (1995). Molecular biology of gastric cancer. World J Surg 19: 484–490.
  Article CAS Google Scholar
• Takeichi, M. (1977). Functional correlation between cell adhesive properties and some cell surface proteins. J Cell Biol 75: 464–474.
  Article CAS Google Scholar
• Takeichi, M. (1991). Cadherin cell adhesion receptors as morphogenetic regulators. Science 251: 1451–1455.
  Article CAS Google Scholar
• Tamura, G., Maesawa, C., Suzuki, Y., Tamada, H., Satoh, M., Ogasawara, S., Kashiwaba, M. & Satodate, R. (1994). Mutations of the APC gene occur during early stages of gastric adenoma development. Cancer Res 54: 1149–1115.
  CAS PubMed Google Scholar
• Umbas, R., Schalken, J. A., Aalders, T. W., Carter BSm Karthaus, H. F., Schaafsma, H. E., Debruyue, F. M. & Isaacs, W. B. (1992). Expression of cellular adhesion molecule E-cadherin is reduced or absent in high grade prostate cancer. Cancer Res 52: 5104–5109.
  CAS PubMed Google Scholar
• Volberg, T., Zick, Y., Dror, R., Sabanay, I., Gilon, C., Levtzki, A. & Geiger, B. (1992). The effect of tyrosine-specific protein phosphorylation in the assembly of adherens-type junctions. EMBO J 11: 1733–1742.
  Article CAS Google Scholar
• Wilding, J., Vousden, K. H., Soutter, P., McCrea, P. D., Del Buono, R. & Pignatelli, M. (1996). E-cadherin transfection down-regulates the epidermal growth factor receptor and reverses the invasiv phenotype of human papilloma virus transfected keratinocytes. Cancer Res 56: 5285–5292.
  CAS PubMed Google Scholar
• Yap, A. S., Niessen, C. M. & Gumbiner, B. M. (1998). The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J Cell Biol 141: 779–789.
  Article CAS Google Scholar

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