Immune reconstitution following hematopoietic progenitor cell transplantation: challenges for the future (original) (raw)
Ochs L, Shu XO, Miller J et al. Late infections after allogeneic bone marrow transplantations: comparison of incidence in related and unrelated donor transplant recipients. Blood 1995; 86: 3979–3986. CASPubMed Google Scholar
Roy V, Ochs L, Weisdorf D . Late infections following allogeneic bone marrow transplantation: suggested strategies for prophylaxis. Leuk Lymphoma 1997; 26: 1–15. ArticleCASPubMed Google Scholar
Storek J, Espino G, Dawson MA et al. Low B-cell and monocyte counts on day 80 are associated with high infection rates between days 100 and 365 after allogeneic marrow transplantation. Blood 2000; 96: 3290–3293. CASPubMed Google Scholar
Chen CS, Boeckh M, Seidel K et al. Incidence, risk factors, and mortality from pneumonia developing late after hematopoietic stem cell transplantation. Bone Marrow Transplant 2003; 32: 515–522. ArticlePubMed Google Scholar
Storek J . B-cell immunity after allogeneic hematopoietic cell transplantation. Cytotherapy 2002; 4: 423–424. ArticleCASPubMed Google Scholar
Storek J, Viganego F, Dawson MA et al. Factors affecting antibody levels after allogeneic hematopoietic cell transplantation. Blood 2003; 101: 3319–3324. ArticleCASPubMed Google Scholar
Miller RA, Stutman O . T cell repopulation from functionally restricted splenic progenitors: 10 000-fold expansion documented by using limiting dilution analyses. J Immunol 1984; 133: 2925–2932. CASPubMed Google Scholar
Mackall CL, Gress RE . Pathways of T-cell regeneration in mice and humans: implications for bone marrow transplantation and immunotherapy. Immunol Rev 1997; 157: 61–72. ArticleCASPubMed Google Scholar
Fry TJ, Christensen BL, Komschlies KL et al. Interleukin-7 restores immunity in athymic T-cell-depleted hosts. Blood 2001; 97: 1525–1533. ArticleCASPubMed Google Scholar
Hakim FT, Cepeda R, Kaimei S et al. Constraints on CD4 recovery post chemotherapy in adults: thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells. Blood 1997; 90: 3789–3798. CASPubMed Google Scholar
Mackall CL, Bare CV, Titus JA et al. Thymic-independent T cell regeneration occurs via antigen driven expansion of peripheral T cells resulting in a repertoire that is limited in diversity and prone to skewing. J Immunol 1996; 156: 4609–4616. CASPubMed Google Scholar
Goldrath AW, Bevan MJ . Low-affinity ligands for the TCR drive proliferation of mature CD8+ T cells in lymphopenic hosts. Immunity 1999; 11: 183–190. ArticleCASPubMedPubMed Central Google Scholar
Goldrath AW, Bevan MJ . Selecting and maintaining a diverse T-cell repertoire. Nature 1999; 402: 255–262. ArticleCASPubMed Google Scholar
Weinberg K, Blazar BR, Wagner JE et al. Factors affecting thymic function after allogeneic hematopoietic stem cell transplantation. Blood 2001; 97: 1458–1466. ArticleCASPubMed Google Scholar
Douek DC, Vescio RA, Betts MR et al. Assessment of thymic output in adults after haematopoietic stem-cell transplantation and prediction of T-cell reconstitution. Lancet 2000; 355: 1875–1881. ArticleCASPubMed Google Scholar
Roux E, Helg C, Fumont-Girard F et al. Analysis of T cell repopulation after allogeneic bone marrow transplantation: significant differences between recipients of T-cell depleted and unmanipulated grafts. Blood 1996; 87: 3984–3992. CASPubMed Google Scholar
Zinkernagel RM, Althage A, Callahan G, Welsh RM . On the immunocompetence of H-2 incompatible irradiation bone marrow chimeras. J Immunol 1980; 124: 2356–2365. CASPubMed Google Scholar
Ghayur T, Seemayer TA, Xenocostas A, Lapp WS . Complete sequential regeneration of graft-vs-host induced severely dysplastic thymuses. Implications for the pathogenesis of chronic graft-vs-host disease. Am J Pathol 1988; 133: 39–46. CASPubMedPubMed Central Google Scholar
Fukushi N, Arase H, Wang B et al. Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance. PNAS 1990; 87: 6301–6305. ArticleCASPubMedPubMed Central Google Scholar
Brochu S, Rioux-Masse B, Roy J et al. Massive activation-induced cell death of alloreactive T cells with apoptosis of bystander postthymic T cells prevents immune reconstitution in mice with graft-versus-host disease. Blood 1999; 94: 390–400. CASPubMed Google Scholar
Porter DL, Collins RH, Hardy C et al. Treatment of relapsed leukemia after unrelated donor marrow transplantation with unrelated donor leukocyte infusions. Blood 2000; 95: 1214–1221. CASPubMed Google Scholar
Dazzi F, Szydlo RM, Goldman JM . Donor lymphocyte infusions for relapse of chronic myeloid leukemia after allogeneic stem cell transplant: where we now stand. Exp Hematol 1999; 27: 1477–1486. ArticleCASPubMed Google Scholar
Helg C, Starobinski M, Jeannet M, Chapuis B . Donor lymphocyte infusion for the treatment of relapse after allogeneic hematopoietic stem cell transplantation. Leuk Lymphoma 1998; 29: 301–313. ArticleCASPubMed Google Scholar
Dudley ME, Wunderlich JR, Robbins PF et al. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science 2002; 298: 850–854. ArticleCASPubMedPubMed Central Google Scholar
Molldrem JJ, Lee PP, Wang C et al. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nat Med 2000; 6: 1018–1023. ArticleCASPubMed Google Scholar
Min D, Taylor PA, Panoskaltsis-Mortari A et al. Protection from thymic epithelial cell injury by keratinocyte growth factor: a new approach to improve thymic and peripheral T-cell reconstitution after bone marrow transplantation. Blood 2002; 99: 4592–4600. ArticleCASPubMed Google Scholar
Puel A, Ziegler SF, Buckley RH, Leonard WJ . Defective IL7R expression in T(−)B(+)NK(+) severe combined immunodeficiency. Nat Genet 1998; 20: 394–397. ArticleCASPubMed Google Scholar
Fry TJ, Moniuszko M, Creekmore S et al. IL-7 therapy dramatically alters peripheral T-cell homeostasis in normal and SIV-infected nonhuman primates. Blood 2003; 101: 2294–2299. ArticleCASPubMed Google Scholar
Sinha ML, Fry TJ, Fowler DH et al. Interleukin 7 worsens graft-versus-host disease. Blood 2002; 100: 2642–2649. ArticleCASPubMed Google Scholar
Fry TJ, Sinha M, Milliron M et al. Flt 3 ligand enhances thymic-dependent and thymic-independent immune reconstitution. Blood 2004; 104: 2794–2800. ArticleCASPubMed Google Scholar
Ruggeri L, Capanni M, Urbani E et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002; 295: 2097–2100. ArticleCASPubMed Google Scholar
Napolitano LA, Lo JC, Gotway MB et al. Increased thymic mass and circulating naive CD4T cells in HIV-1-infected adults treated with growth hormone. AIDS 2002; 16: 1103–1111. ArticleCASPubMed Google Scholar
Olsen NJ, Kovacs WJ . Effects of androgens on T and B lymphocyte development. Immunol Res 2001; 23: 281–288. ArticleCASPubMed Google Scholar