Comparison of gastric emptying of a solid and a liquid nutritional rehabilitation food (original) (raw)

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• Published: 30 August 2001

European Journal of Clinical Nutrition volume 55, pages 769–772 (2001)Cite this article

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Abstract

Objective: To compare gastric emptying of a solid and a liquid nutritional rehabilitation food.

Design: Cross-over trial. Eight volunteers took, in random order at least 1 week apart, 2100 kJ of a solid and a liquid nutritional rehabilitation food with added labelled [13C] glycine.

Setting: Research ward for healthy volunteers.

Subjects: Eight healthy volunteers.

Methods: Appearance of 13CO2 was monitored in expired gas every 15 min for 240 min after meal intake and compared between solid and liquid meals. Parameters of gastric emptying were then calculated.

Results: Gastric half-emptying time was slightly longer for solid meal compared to liquid meal (101±6.0 vs 88±9.8 min, _P_=0.24). 13CO2 excretion peaked 138±5.3 min after the solid meal compared with 119±8.6 min with liquid meal (_P_=0.06). 13CO2 excretion was higher for the liquid food up to 110 min after the meal but then became higher for the solid food. Analysis of variance for repeated measures of 13CO2 excretion showed a significant interaction term between the type of food and time indicating a delayed elimination of 13CO2 for the solid food (_P_=0.018).

Conclusions: Attempts to replace liquid nutritional rehabilitation foods by a solid food in malnourished patients should take into account a possible slower gastric emptying.

Sponsorship: Supported by a grant from Nutriset (Malaunay, France) and ANVAR (Agence Nationale de la Valorisation de la Recherche, contract no. A9703021P).

European Journal of Clinical Nutrition (2001) 55, 769–772

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Acknowledgements

We are grateful to Mrs Franchisseur and Mrs Maurel for their help and support during the study.

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Author notes

1. A Briend: Guarantor: A Briend.
2. L Achour, S Méance and A Briend: Contributors: All investigators were involved in the design, conduct and writing of the study. CA and SM measured 13CO2 excretion by mass spectrometry. AB initiated the project and carried out the data analysis

Authors and Affiliations

1. Département des Sciences Biologiques, Faculté des Sciences, Monastir, Tunisia
   L Achour
2. Institut Scientifique et Technique de la Nutrition et de l'Alimentation, Conservatoire National des Arts et Métiers, Paris, France
   S Méance & A Briend
3. Institut de Recherche pour le Développement, Paris, France
   A Briend

Authors

1. L Achour
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2. S Méance
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3. A Briend
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Correspondence toA Briend.

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Achour, L., Méance, S. & Briend, A. Comparison of gastric emptying of a solid and a liquid nutritional rehabilitation food.Eur J Clin Nutr 55, 769–772 (2001). https://doi.org/10.1038/sj.ejcn.1601221

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• Received: 12 October 2000
• Revised: 14 February 2001
• Accepted: 28 February 2001
• Published: 30 August 2001
• Issue Date: 01 September 2001
• DOI: https://doi.org/10.1038/sj.ejcn.1601221

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