Immune-mediated destruction of transfected myocytes following DNA vaccination occurs via multiple mechanisms (original) (raw)

• Davis HL, Michel ML, Whalen RG . DNA-based immunization induces continuous secretion of hepatitis B surface antigen and high levels of circulating antibody Hum Molec Genet 1993 2: 1847–1851
  Article CAS PubMed Google Scholar
• Davis HL et al. Direct gene transfer in skeletal muscle: plasmid DNA-based immunization against the hepatitis B virus surface antigen Vaccine 1994 12: 1503–1509
  Article CAS PubMed Google Scholar
• Davis HL, Schirmbeck R, Reimann J, Whalen RG . DNA-mediated immunization in mice induces a potent MHC class I-restricted cytotoxic T lymphocyte response to the hepatitis B envelope protein Hum Gene Ther 1995 6: 1447–1456
  Article CAS PubMed Google Scholar
• Kowalczyk DW, Ertl HC . Immune responses to DNA vaccines Cell Mol Life Sci 1999 55: 751–770
  Article CAS PubMed Google Scholar
• Davis HL, Mancini M, Michel ML, Whalen RG . DNA-mediated immunization to hepatitis B surface antigen: longevity of primary response and effect of boost Vaccine 1996 14: 910–915
  Article CAS PubMed Google Scholar
• Wolff JA et al. Long-term persistence of plasmid DNA and foreign gene expression in mouse muscle Hum Mol Genet 1992 1: 363–369
  Article CAS PubMed Google Scholar
• Cheng L, Ziegelhoffer PR, Yang NS . In vivo promoter activity and transgene expression in mammalian somatic tissues evaluated by using particle bombardment Proc Natl Acad Sci USA 1993 90: 4455–4459
  Article CAS PubMed PubMed Central Google Scholar
• Davis HL, Millan CL, Watkins SC . Immune-mediated destruction of transfected muscle fibers after direct gene transfer with antigen-expressing plasmid DNA Gene Therapy 1997 4: 181–188
  Article CAS PubMed Google Scholar
• Zijlstra M et al. Beta 2-microglobulin deficient mice lack CD4–8+ cytolytic T cells Nature 1990 344: 742–746
  Article CAS PubMed Google Scholar
• Grusby MJ, Johnson RS, Papaioannou VE, Glimcher LH . Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice Science 1991 253: 1417–1420
  Article CAS PubMed Google Scholar
• Klavinskis LS, Barnfield C, Gao L, Parker S . Intranasal immunization with plasmid DNA–lipid complexes elicits mucosal immunity in the female genital and rectal tracts J Immunol 1999 162: 254–262
  CAS PubMed Google Scholar
• Schirmbeck R et al. Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice J Virol 1995 69: 5929–5934
  CAS PubMed PubMed Central Google Scholar
• Harty JT, Tvinnereim AR, White DW . CD8+ T cell effector mechanisms in resistance to infection Annu Rev Immunol 2000 18: 275–308
  Article CAS PubMed Google Scholar
• Gholson CF, Siddiqui A, Vierling JM . Cell surface expression of hepatitis B surface and core antigens in transfected rat fibroblast cell lines Gastroenterology 1990 98: 968–975
  Article CAS PubMed Google Scholar
• Chu CM, Liaw YF . Membrane staining for hepatitis B surface antigen on hepatocytes: a sensitive and specific marker of active viral replication in hepatitis B J Clin Pathol 1995 48: 470–473
  Article CAS PubMed PubMed Central Google Scholar
• Satoh O et al. Membrane structure of the hepatitis B virus surface antigen particle J Biochem (Tokyo) 2000 127: 543–550
  Article CAS Google Scholar
• Michalak TI et al. Antibody-directed complement-mediated cytotoxicity to hepatocytes from patients with chronic hepatitis B Clin Exp Immunol 1995 100: 227–232
  Article CAS PubMed PubMed Central Google Scholar
• Daeron M . Fc receptor biology Annu Rev Immunol 1997 15: 203–234
  Article CAS PubMed Google Scholar
• Machy P, Serre K, Leserman L . Class I-restricted presentation of exogenous antigen acquired by Fcgamma receptor-mediated endocytosis is regulated in dendritic cells Eur J Immunol 2000 30: 848–857
  Article CAS PubMed Google Scholar
• Mitchell DA, Nair SK, Gilboa E . Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells (published erratum appears in Eur J Immunol 1998; 28: 3891) Eur J Immunol 1998 28: 1923–1933
  Article CAS PubMed Google Scholar
• Knight SC, Askonas BA, Macatonia SE . Dendritic cells as targets for cytotoxic T lymphocytes Adv Exp Med Biol 1997 417: 389–394
  Article CAS PubMed Google Scholar
• Parajuli P et al. Cytolysis of human dendritic cells by autologous lymphokine-activated killer cells: participation of both T cells and NK cells in the killing J Leukoc Biol 1999 65: 764–770
  Article CAS PubMed Google Scholar
• Cavazzana-Calvo M et al. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease Science 2000 28: 669–672
  Article Google Scholar
• Wilson CB, Embree LJ, Schowalter D et al. Transient inhibition of CD28 and CD40 ligand interactions prolongs adenovirus-mediated transgene expression in the lung and facilitates expression after secondary vector administration J Virol 1998 72: 7542–7550
  CAS PubMed PubMed Central Google Scholar
• Halbert CL, Standaert TA, Wilson CB, Miller AD . Successful readministration of adeno-associated virus vectors to the mouse lung requires transient immunosuppression during the initial exposure J Virol 1998 72: 9795–9805
  CAS PubMed PubMed Central Google Scholar
• Kagi D et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice Nature 1994 369: 31–37
  Article CAS PubMed Google Scholar
• Davis HL, Whalen RG, Demeneix BA . Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression Hum Gene Ther 1993 4: 151–159
  Article PubMed Google Scholar
• Krieg AM et al. Sequence motifs in adenoviral DNA block immune activation by stimulatory CpG motifs Proc Natl Acad Sci USA 1998 95: 12631–12636
  Article CAS PubMed PubMed Central Google Scholar
• Davis HL et al. Plasmid DNA is superior to viral vectors for direct gene transfer into adult mouse skeletal muscle Hum Gene Ther 1993 4: 733–740
  Article CAS PubMed Google Scholar
• Bradford MM . A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 1976 72: 248–254
  Article CAS PubMed Google Scholar
• Davis HL et al. CpG DNA is a potent enhancer of specific immunity in mice immunized with recombinant hepatitis B surface antigen J Immunol 1998 160: 870–876
  CAS PubMed Google Scholar