GABAA and Opioid Receptors of the Central Nucleus of the Amygdala Selectively Regulate Ethanol-Maintained Behaviors (original) (raw)
Alheid GF, Heimer L (1988). New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: the striatopallidal, amygdaloid, and corticopetal components of substantia innominata. Neuroscience27: 1–39. ArticleCAS Google Scholar
Araki T, Tohyama M (1992). Region-specific expression of GABAA receptor _α_3 and _α_4 subunits mRNAs in the rat brain. Mol Brain Res12: 295–314. Article Google Scholar
Baldwin HA, Wall TL, Schuckit MA, Koob GF (1991). Differential effects of ethanol on punished responding in the P and NP rats. Alcoholism: Clin Exp Res15: 700–704. ArticleCAS Google Scholar
Bals-Kubic R, Ableitner A, Herz A, Shippenberg TS (1993). Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats. J Pharmcol Exp Ther264: 489–495. Google Scholar
Bowen CA, Grant KA (1998). Pharmacological analysis of the heterogeneous discriminative stimulus effects of ethanol in rats using a three-choice ethanol–dizocilpine–water discrimination. Psychopharmacology (Berlin)139: 86–94. ArticleCAS Google Scholar
Carroll ME, Carmona G, May SA (1991). Modifying drug-reinforced behavior by altering the economic conditions of the drug and a non-drug reinforcer. J Exp Anal Behav18: 361–376. Article Google Scholar
Carroll ME, Morgan AD, Lynch WJ, Campbell UC, Dess NK (2002). Intravenous cocaine and heroin self-administration in rats selectively bred for differential saccharin intake: phenotype and sex differences. Psychopharmacology161: 304–313. ArticleCAS Google Scholar
Carroll MR, Woods JE, Seyoum RA, June HL (2001). The role of the GABAA _α_1 subtype in mediating the sedative and anxiolytic properties of benzodiazepines. Alcoholism: Clin Exp Res25, (abstract 34).
Churchill L, Kalivas PW (1992). Dopamine depletion produces augmented behavioral responses to a mu-, but not a delta-opioid receptor agonist in the nucleus accumbens: lack of a role for receptor upregulation. Synapse11: 47–57. ArticleCAS Google Scholar
Cloninger CR (1987). Neurogenetic adaptive mechanisms in alcoholism. Science236: 410–416. ArticleCAS Google Scholar
Cox ED, Diaz-Arauzo H, Qi H, Reddy MS, Chunrong M, Harris B et al (1998). Synthesis and evaluation of analogues of the partial agonist 6-(propyloxy)-4-(methoxymethyl)-_β_-carboline-3carboxylic acid ethyl ester (6-PBC) and full agonist 6-(benzyloxy)-4-(methoxymethyl)-_β_-carboline-3-carboxylic acid ethyl ester (ZK 93423) at wild type and recombinant GABAA receptors. J Med Chem41: 2537–2552. ArticleCAS Google Scholar
Cox ED, Hagen TJ, McKernan R, Cook JM (1995). BZ1 receptor specific ligands. Synthesis and biological properties of _β_CCt, a BZ1 receptor subtype specific antagonist. Med Chem Res5: 710–718. CAS Google Scholar
Cummings R, Garcia M, Mason D, Mc Kay PF, Foster KL, June HL (1999). Differential effects of unilateral versus bilateral microinjections of nalmefene in the nucleus accumbens and ventral tegmental area in alcohol-preferring (P) rats. Alcoholism Clin Exp Res22: 16A (Abstract #62). Google Scholar
Duncan GE, Breese GR, Criswell HE, Me Cown TJ, Herbert JS, Devaud LL et al (1995). Distribution of [3H] zolpidem binding sites in relation to messenger RNA encoding the _α_1, _β_2 and _γ_2 subunits of GABAA receptors in rat brain. Neuroscience64: 1113–1128. ArticleCAS Google Scholar
Freedman LJ, Cassell MD (1994). Distribution of dopamine fibers in the central division of the extended amygdala of the rat. Brain Res633: 234–252. Article Google Scholar
Fritschy JM, Möhler H (1995). GABAA-receptor heterogeneity in the adult rat brain: differential regional and cellular distribution of seven major subunits. J Comp Neurol359: 154–194. ArticleCAS Google Scholar
Gonzales C, Chesselet MF (1991). Amygdalonigral pathway: an anterograde study in the rat with Phaseolus vulgaris leucoagglutinin (PHA-L). J Comp Neurol297: 182–200. Article Google Scholar
Griebel G, Perrault G, Letang V, Granger P, Avenet P, Schoemaker H et al (1999). New evidence that the pharmacological effects of benzodiazepine receptor ligands can be associated with activities at different BZ (ω) receptor subtypes. Psychopharmacology146: 205–213. ArticleCAS Google Scholar
Harvey SC, Foster KL, McKay PF, Carroll M, Seyoum R, Woods, JE et al (2002). The GABAA receptor _α_1 subtype in the ventral pallidum regulates EtOH-seeking behaviors. J Neurosci22: 3766–3775. Article Google Scholar
Heyser CJ, Roberts AJ, Schulteis G, Koob GF (1999). Central administration of an opiate antagonist decreases oral ethanol self-administration in rats. Alcoholism: Clin Exp Res23: 1468–1476. ArticleCAS Google Scholar
Higgs S, Cooper SJ (1995). Benzodiazepine receptor inverse agonists and ingestive behaviors: the palatability hypothesis. In: Sarter M, Nutt DJ, Lister RG (eds). Benzodiazepine Receptor Inverse Agonists. Wiley-Liss: New York. pp 163–184. Google Scholar
Hodge CW, Chappelle AN, Samson HH (1995). GABAergic transmission in the nucleus accumbens is involved in the termination of ethanol self-administration in rats. Alcoholism: Clin Exp Res19: 1486–1493. ArticleCAS Google Scholar
Hodge CW, Cox AA (1998). The discriminative stimulus effects of ethanol are mediated by NMDA and GABA (A) receptors in specific limbic brain regions. Psychopharmacology (Berlin)139: 95–107. ArticleCAS Google Scholar
Honkaniemi J (1992). Colocalization of peptide- and tyrosine-hydroxylase-like immunoreactivities with Fos-immunoreactive neurons in the rat central amygdaloid nucleus after immobilization stress. Brain Res598: 107–113. ArticleCAS Google Scholar
Hwang BH, Lumeng L, Wu JY, Li TK (1990). Increased number of GABAergic terminals in the nucleus accumbens is associated with alcohol preference in rats. Alcoholism: Clin Exp Res14: 503–507. ArticleCAS Google Scholar
Hyytiä P, Kiiamnaa K (2001). Suppression of ethanol responding by centrally administered CTOP and naltrindole in AA and Wistar rats. Alcoholism: Clin Exp Res25: 25–33. Article Google Scholar
Hyytiä P, Koob GF (1995). GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats. Eur J Pharmacol283: 151–159. Article Google Scholar
June HL (2002). Alcohol initiation procedures in rats: methods used in evaluating potential pharmacotherapeutic agents. In: Crawley J, Gerfen C, Mc Kay R, Rogawski M, Sibley D, Skolnick P (eds). Current Protocols in Neuroscience. John Wiley and Sons: New York. pp 9–23. Google Scholar
June HL, Grey C, Johnson TB, Williams L, Mc Kay P, Rock S et al (1998b). GABAergic substrates in the nucleus accumbens and dorsal hippocampus mediate responding maintained by EtOH presentation in alcohol-preferring (P) rats. Behav Pharmacol9: S47. Google Scholar
June HL, Grey C, Warren-Reese C, Durr LF, Ricks-Cord A, Johnson A et al (1998c). The opioid receptor antagonist nalmefene reduces responding maintained by ethanol presentation: preclinical studies in ethanol-preferring and outbred Wistar rats. Alcoholism: Clin Exp Res22: 2174–2185. CAS Google Scholar
June HL, Grey C, Warren-Reese C, Ricks A, Cason CR (1998a). The effects of the novel benzodiazepine receptor inverse agonist Ru 34000 on ethanol-maintained responding. Eur J Pharmacol350: 151–158. ArticleCAS Google Scholar
June HL, Harvey SC, Foster KL, Mc Kay PF, Cummings R, Garcia M et al (2001). GABAA receptors containing _α_5 subunits in the CA1 and CA3 hippocampal fields regulate ethanol-motivated behaviors: an extended ethanol reward circuitry. J Neurosci21: 2166–2177. ArticleCAS Google Scholar
June HL, Harvey SC, Foster KL, McKay PF, Woods JE, Carroll MR et al (2003). Alcohol reward is mediated by the GABAA receptor _α_1 subtype in the ventral pallidum.
Kalivas PW (1993). Neurotransmitter regulation of dopamine neurons in the VTA. Brain Res Rev18: 75–113. ArticleCAS Google Scholar
Kalivas PW, Duffy P, Eberhardt H (1990). Modulation of A10 dopamine neurons by GABA agonists. J Pharmacol Exp Ther253: 858–866. CASPubMed Google Scholar
Koob GF (1999). The role of the striatopallidal and extended amygdale systems in drug addiction. Ann NY Acad Sci877: 445–460. ArticleCAS Google Scholar
Koob GF, Le Moal M (1997). Drug Abuse: hedonic homeostatic dysregulation. Science278: 52–58. ArticleCAS Google Scholar
Koob GF, Roberts AJ, Schulteis G, Parsons LU, Heyser CJ, Hyyti P et al (1998a). Neurocircuitry targets in ethanol reward and dependence. Alcoholism: Clin Exp Res22: 3–9. ArticleCAS Google Scholar
Koob GF, Sanna PP, Bloom FE (1998b). Neuroscience of addiction. Neuron21: 467–476. ArticleCAS Google Scholar
Kosaka T, Kosaka K, Hataguchi Y, Nagatsu I, Wu JY, Ottersen OP et al (1987). Catecholaminergic neurons containing GABA-like and/or glutamic acid decarboxylase-like immunoreactivities in various brain regions of the rat. Exp Brain Res66: 191–210. ArticleCAS Google Scholar
Lankford MF, Myers RD (1994). Genetics of alcoholism: simultaneous presentation of a chocolate drink diminishes alcohol preference in high drinking HAD rats. Pharmacol Biochem Behav49: 417–425. ArticleCAS Google Scholar
Lewis MJ, June HL (1990). Neurobehavioral studies of ethanol reward and activation. Alcohol7: 213–219. ArticleCAS Google Scholar
Lüddens H, June HL, Cook JM, (In Preparation). _β_CCt produces agonist and antagonist effects in the in vivo HEK cells assay.
Lumeng L, Murphy JM, McBride WJ, Li T-K (1995). Genetic influences on alcohol preference in animals. In: Begleiter H (eds). The Genetics of Alcoholism. Oxford, New York. pp 165–201. Google Scholar
Mansour A, Fox CA, Akil H, Watson SJ (1995). Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications. Trends Neurosci18: 22–29. ArticleCAS Google Scholar
Mansour A, Khachaturian H, Lewis ME, Akil H, Watson SJ (1987). Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. J Neurosc7: 2445–2464. CAS Google Scholar
McBride WJ (2002). Central nucleus of the amygdala and the effects of alcohol and alcohol-drinking behavior in rodents. Pharmacol Biochem Behav71: 509–515. ArticleCAS Google Scholar
McBride WJ, Li TK (1998). Animals models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit Rev Neurobiol12: 339–369. ArticleCAS Google Scholar
McBride WJ, Murphy JM, Lumeng L, Li TK (1988). Effects of Ro-4513, fluoxetine and desipramine on the intake of ethanol, water and food by the alcohol-preferring (P) and non-preferring (NP) lines of rats. Pharmacol Biochem Behav30: 104–150. Article Google Scholar
McDonald AJ (1982). Cytoarchitecture of the central amygdaloid nucleus of the rat. J Comp Neurol208: 401–418. ArticleCAS Google Scholar
McKernan RM, Rosahl TW, Reynolds DS, Sur C, Waffold KA, Atack JR et al (2000). Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABAA receptor _α_1 subtype. Nature3: 587–592. CAS Google Scholar
McKinzie DL, Eha R, Murphy JM, Mc Bride WJ, Lumeng L, Li TK (1996). Effects of taste aversion training on the acquisition of alcohol drinking in adolescent P and HAD lines. Alcoholism: Clin Exp Res20: 682–687. ArticleCAS Google Scholar
Minano FJ, Meneres S, Sancibrian M, Salinas P, Myers RD (1992). GABAA receptors in the amygdala: role in feeding in fasted and satiated rats. Brain Res586: 104. ArticleCAS Google Scholar
Möeller C, Wiklund L, Wolfgang S, Thorsell A, Helilig M (1997). Decreased experimental anxiety and voluntary ethanol consumption in rats following central but not basolateral amygdala lesions. Brain Res760: 94–101. Article Google Scholar
Morales M, Criado JR, Sanna PP, Henrikson SJ, Bloom FE (1998). Acute ethanol induces c-fos immunoreactivity in GABAergic neurons of the central nucleus of the amygdala. Brain Res798: 333–336. ArticleCAS Google Scholar
Murphy JM, Stewart RB, Bell RL, Badia-Elder NE, Carr LG, Mc Bride WJ et al (2002). Phenotypic and genotypic characterization of the Indiana University rat lines selectively bred for high and low preference. Behav Genet32: 363–388. Article Google Scholar
Nowak KL, Mc Bride WJ, Lumeng L, Li T.K, Murphy JM (1998). Blocking GABAA receptors in the anterior ventral tegmental area attenuates ethanol intake of the alcohol-preferring P rat. Psychopharmacology139: 108–116. ArticleCAS Google Scholar
Oertel WH, Reithmuller G, Mugnaini E, Schmechel A, Weindl C, Gramsch C et al (1983). Opioid peptide-like immunoreactivity localized in GABAergic neurons of rat neostriatum and central amygdaloid nucleus. Life Sci33: 73–76. ArticleCAS Google Scholar
Paden CM, Krall S, Lynch WC (1987). Heterogeneous distribution and upregulation of mu, delta and kappa receptors in the amygdala. Brain Res418: 349–355. ArticleCAS Google Scholar
Paronis CA, Cox ED, Cook JM, Bergman J (2001). Different types of GABAA receptors may mediate the anticonflict and response rate-decreasing effects of zaleplon, zolpidem, and midazolam in squirrel monkeys. Psychopharmacology (Berlin)156: 461–468. ArticleCAS Google Scholar
Paxinos G, Watson C (1998). The Rat Brain in Stereotaxic Coordinates. Academic Press: Sydney. Google Scholar
Petry NM, Heyman GM (1995). Behavioral economic analysis of concurrent ethanol/sucrose and sucrose reinforcement in the rat: effects of altering variable ratio requirements. J Exp Anal Behav64: 331–359. ArticleCAS Google Scholar
Pohorecky LA (1990). Interaction of ethanol and stress: research with experimental animals—an update. Alcohol Alcoholism25: 263–276. ArticleCAS Google Scholar
Porrino LJ, Williams-Hemby L, Whitlow C, Bowen C, Samson HH (1998). Metabolic mapping of the effects of oral alcohol self-administration in rats. Alcohol: Clin Exp Res22: 176–182. CAS Google Scholar
Rowlett JK, Tornatzky W, Cook JM, Ma C, Miczek KA (2001). Zolpidem, triazolam, and diazepam decrease vocalizations in mouse pups: differential antagonism by flumazenil and _β_-Carboline-3-carboxylate-_t_-butyl ester (_β_-CCt). J Pharmacol Exp Therap297: 247–253. CAS Google Scholar
Salimov RM, Mc Bride WJ, McKinzie DL, Lumeng L, Li TK (1996). Effects of ethanol consumption by adolescent alcohol-preferring P rats on subsequent behavioral performance in the cross-maze and slip funnel tests. Alcohol13: 297–300. ArticleCAS Google Scholar
Sanders SK, Shekhar A (1995). Regulation of anxiety by GABAA receptors in the rat amygdala. Pharmacol Biochem Behav52: 701–706. ArticleCAS Google Scholar
Sanger DJ, Benavides J, Perrault G, Morel E, Cohen C, Joly D et al (1994). Recent developments in the behavioral pharmacology of benzodiazepine (omega) receptors: evidence for the functional significance of receptor subtypes. Neurosci Biobehav Rev18: 355–372. ArticleCAS Google Scholar
Shannon HE, Guzman F, Cook JM (1984). Carboline-3-carboxylate-t-butyl ester: a selective BZ1 benzodiazepine receptor antagonist. Life Sci35: 2227–2236. ArticleCAS Google Scholar
Stewart RB, Gatto GJ, Lumeng L, Li TK, Murphy JM (1993). Comparison of alcohol-preferring P and nonpreferring NP rats on tests of anxiety and for the anxiolytic effects of ethanol. Alcohol10: 1–10. ArticleCAS Google Scholar
Sun N, Cassell MD (1993). Intrinsic GABAergic neurons in the rat central extended amygdala. J Comp Neurol330: 381–404. ArticleCAS Google Scholar
Sun N, Yi H, Cassell MD (1994). Evidence for a GABAergic interface between cortical afferents and brainstem projection neurons in the rat central extended amygdala. J Comp Neurol340: 43–64. ArticleCAS Google Scholar
Turner JD, Bodewitz G, Thompson CL, Stephenson FA (1993). Immunohistochemical mapping of gamma-aminobutyric acid type-A receptor alpha subunits in rat central nervous system. In: Stephens DN (ed) Anxiolytic β-carbolines: From Molecular Biology to the Clinic. Springer-Verlag: New York. pp 29–49. Chapter Google Scholar
Veinante P, Stoeckel ME, Freund-Mercier MJ (1997). GABA and peptide-immunoreactivities colocalize in the rat central extended amygdala. Neuroreport8: 2985–2989. ArticleCAS Google Scholar
Weiss F, Lorang MT, Bloom FE, Koob GF (1993). Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetics and motivational determinants. J Pharmacol Exp Ther267: 250–258. CAS Google Scholar
Wilson MA (1992). Influences of gender, gonadectomy, and estrous cycle in GABA/BZ receptors and benzodiazepine responses in rats. Brain Res Bull29: 165–172. ArticleCAS Google Scholar
Wilson MA, Biscardi R (1992). Effects of gender and gonadectomy on responses to chronic benzodiazepine receptor agonist exposure in rats. Eur J Pharmacol215: 99–107. ArticleCAS Google Scholar
Wisden H, Laurie DJ, Monyer H, Seeburg PH (1992). The distribution of 13 GABAA receptor subunit mRNAs in the rat brain: telencephalon, diencephalon, mesencephalon. J Neurosci12: 1040–1062. ArticleCAS Google Scholar
Yin W, Carroll M, June HL, Cook JM (2001). Alcohol's euphoric properties are regulated by the GABAA-_α_1 subtype. Paper Presented at the Committee on Problems of Drug Dependence 63rd Annual Meeting, Scottsdale, AZ, June 11-20.