RETRACTED ARTICLE: Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity (original) (raw)

• Alessi DR, James SR, Downes CP, Holmes AB, Gaffney PR, Reese CB et al. (1997). Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha. Curr Biol 7: 261–269.
  Article CAS Google Scholar
• Bader AG, Kang S, Zhao L, Vogt PK . (2005). Oncogenic PI3K deregulates transcription and translation. Nat Rev Cancer 5: 921–929.
  Article CAS Google Scholar
• Bentires-Alj M, Hellin AC, Ameyar M, Chouaib S, Merville MP, Bours V . (1999). Stable inhibition of nuclear factor kappaB in cancer cells does not increase sensitivity to cytotoxic drugs. Cancer Res 59: 811–815.
  CAS PubMed Google Scholar
• Biggs III WH, Meisenhelder J, Hunter T, Cavenee WK, Arden KC . (1999). Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci USA 96: 7421–7426.
  Article CAS Google Scholar
• Bradford MM . (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248–254.
  Article CAS Google Scholar
• Brown DM, Ruoslahti E . (2004). Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. Cancer Cell 5: 365–374.
  Article CAS Google Scholar
• Chen X, Thakkar H, Tyan F, Gim S, Robinson H, Lee C et al. (2001). Constitutively active Akt is an important regulator of TRAIL sensitivity in prostate cancer. Oncogene 20: 6073–6083.
  Article CAS Google Scholar
• Damen JE, Liu L, Rosten P, Humphries RK, Jefferson AB, Majerus PW et al. (1996). The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase. Proc Natl Acad Sci USA 93: 1689–1693.
  Article CAS Google Scholar
• Emdad L, Sarkar D, Su ZZ, Randolph A, Boukerche H, Valerie K et al. (2006). Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis. Cancer Res 66: 1509–1516.
  Article CAS Google Scholar
• Festuccia C, Muzi P, Millimaggi D, Biordi L, Gravina GL, Speca S et al. (2005). Molecular aspects of gefitinib antiproliferative and pro-apoptotic effects in PTEN-positive and PTEN-negative prostate cancer cell lines. Endocr Relat Cancer 12: 983–998.
  Article CAS Google Scholar
• Ghosh S, Karin M . (2002). Missing pieces in the NF-_κ_B puzzle. Cell 109: S81–S96.
  Article CAS Google Scholar
• Kang DC, Su ZZ, Sarkar D, Emdad L, Volsky DJ, Fisher PB . (2005). Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1. Gene 353: 8–15.
  Article CAS Google Scholar
• Lee SG, Su ZZ, Emdad L, Sarkar D, Fisher PB . (2006). Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc. Proc Natl Acad Sci USA 103: 17390–17395.
  Article CAS Google Scholar
• Li P, Lee H, Guo S, Unterman TG, Jenster G, Bai W . (2003). AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR. Mol Cell Biol 23: 104–118.
  Article Google Scholar
• Lu T, Burdelya LG, Swiatkowski SM, Boiko AD, Howe PH, Stark GR et al. (2004). Secreted transforming growth factor beta2 activates NF-kappaB, blocks apoptosis, and is essential for the survival of some tumor cells. Proc Natl Acad Sci USA 101: 7112–7117.
  Article CAS Google Scholar
• Lynch RL, Konicek BW, McNulty AM, Hanna KR, Lewis JE, Neubauer BL et al. (2005). The progression of LNCaP human prostate cancer cells to androgen independence involves decreased FOXO3a expression and reduced p27KIP1 promoter transactivation. Mol Cancer Res 3: 163–169.
  Article CAS Google Scholar
• Nakashima H, Nakamura M, Yamaguchi H, Yamanaka N, Akiyoshi T, Koga K et al. (2006). Nuclear factor-kappaB contributes to hedgehog signaling pathway activation through sonic hedgehog induction in pancreatic cancer. Cancer Res 66: 7041–7049.
  Article CAS Google Scholar
• Nakatani K, Thompson DA, Barthel A, Sakaue H, Liu W, Weigel RJ et al. (1999). Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J Biol Chem 274: 21528–21532.
  Article CAS Google Scholar
• Nicholson KM, Anderson NG . (2002). The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal 14: 381–395.
  Article CAS Google Scholar
• Pajonk F, Pajonk K, McBride WH . (1999). Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells. J Natl Cancer Inst 91: 1956–1960.
  Article CAS Google Scholar
• Place RF, Noonan EJ, Giardina C . (2005). HDAC inhibition prevents NF-kappa B activation by suppressing proteasome activity: down-regulation of proteasome subunit expression stabilizes I kappa B alpha. Biochem Pharmacol 70: 394–406.
  Article CAS Google Scholar
• Plas DR, Thompson CB . (2003). Akt activation promotes degradation of tuberin and FOXO3a via the proteasome. J Biol Chem 278: 12361–12366.
  Article CAS Google Scholar
• Su ZZ, Chen Y, Kang DC, Chao W, Simm M, Volsky DJ et al. (2003). Customized rapid subtraction hybridization (RaSH) gene microarrays identify overlapping expression changes in human fetal astrocytes resulting from human immunodeficiency virus-1 infection or tumor necrosis factor-α treatment. Gene 306: 67–78.
  Article CAS Google Scholar
• Su ZZ, Kang DC, Chen Y, Pekarskaya O, Chao W, Volsky DJ et al. (2002). Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH. Oncogene 21: 3592–3602.
  Article CAS Google Scholar
• Takaishi H, Konishi H, Matsuzaki H, Ono Y, Shirai Y, Saito N et al. (1999). Regulation of nuclear translocation of forkhead transcription factor AFX by protein kinase B. Proc Natl Acad Sci USA 96: 11836–11841.
  Article CAS Google Scholar
• Yang L, Xie S, Jamaluddin MS, Altuwaijri S, Ni J, Kim E et al. (2005). Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells. J Biol Chem 280: 33558–33565.
  Article CAS Google Scholar
• Zerbini LF, Wang Y, Cho JY, Libermann TA . (2003). Constitutive activation of nuclear factor kappaB p50/p65 and Fra-1 and JunD is essential for deregulated interleukin 6 expression in prostate cancer. Cancer Res 63: 2206–2215.
  CAS PubMed Google Scholar
• Zhang M, Fang X, Liu H, Wang S, Yang D . (2007). Blockade of AKT activation in prostate cancer cells with a small molecule inhibitor, 9-chloro-2-methylellipticinium acetate (CMEP). Biochem Pharmacol 73: 15–24.
  Article CAS Google Scholar