Silica encapsulated SERS nanoprobe conjugated to the bacteriophage tailspike protein for targeted detection ofSalmonella (original) (raw)
Abstract
Silica-encapsulated Raman-reporter embedded SERS nanoprobes, named nanoaggregate embedded beads (NAEBs), were conjugated to the Salmonella specific tailspike protein (TSP) isolated from the P22 bacteriophage to enable a highly specific and ultrasensitive optical transduction platform. We demonstrate three successful surface conjugation strategies and highlight the detection of a single bacterium using SERS.
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Article information
DOI
https://doi.org/10.1039/C1CC16325F
Article type
Communication
Submitted
11 Oct 2011
Accepted
14 Nov 2011
First published
08 Dec 2011
Download Citation
Chem. Commun., 2012,48, 1024-1026
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Silica encapsulated SERS nanoprobe conjugated to the bacteriophage tailspike protein for targeted detection of_Salmonella_
L. Tay, P. Huang, J. Tanha, S. Ryan, X. Wu, J. Hulse and L. Chau,Chem. Commun., 2012, 48, 1024DOI: 10.1039/C1CC16325F
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